Gallic acid_SW48 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in SW48 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LMO7 LIM domain 7 0.104513
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0945759
AREG amphiregulin 0.0877383
LAMC2 laminin, gamma 2 0.0866142
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0802075
PLAUR plasminogen activator, urokinase receptor 0.0604947
HSPA8 heat shock 70kDa protein 8 0.0598386
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0573431
LAMB3 laminin, beta 3 0.0567478
FAT1 FAT atypical cadherin 1 0.0519035
ANXA1 annexin A1 0.0511585
EGFR epidermal growth factor receptor 0.0506987
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0506921
RPL3 ribosomal protein L3 0.0498565
ITPRID2 ITPR interacting domain containing 2 0.047307
PDE4B phosphodiesterase 4B, cAMP-specific 0.0469344
DSPP dentin sialophosphoprotein 0.0466793
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.0444228
FHL2 four and a half LIM domains 2 0.0431807
EEF2 eukaryotic translation elongation factor 2 0.0419475
AHNAK AHNAK nucleoprotein 0.0407547
LOC102724023 ES1 protein homolog, mitochondrial 0.0406244
RPS2 ribosomal protein S2 0.0386738
TSC22D2 TSC22 domain family, member 2 0.037841
DUSP4 dual specificity phosphatase 4 0.035943
EZR ezrin 0.0349852
ARHGAP42 Rho GTPase activating protein 42 0.0342833
SPRED2 sprouty-related, EVH1 domain containing 2 0.0342559
MAN1A1 mannosidase, alpha, class 1A, member 1 0.033645
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0324963
EVA1C eva-1 homolog C (C. elegans) 0.0313929
GCLC glutamate-cysteine ligase, catalytic subunit 0.0294252
SFPQ splicing factor proline/glutamine-rich 0.029221
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0291074
MYO5B myosin VB 0.0281933
YAP1 Yes-associated protein 1 0.0279595
KLF6 Kruppel-like factor 6 0.0278347
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0274758
RPS12 ribosomal protein S12 0.0261764
USP6NL USP6 N-terminal like 0.0249873
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0249378
ENO1 enolase 1, (alpha) 0.0249211
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.0248043
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0248004
RNF43 ring finger protein 43 0.0247362
ERRFI1 ERBB receptor feedback inhibitor 1 0.0243719
RPS3 ribosomal protein S3 0.0243383
MT2A metallothionein 2A 0.0241125
TXNRD1 thioredoxin reductase 1 0.0229567
MT1X metallothionein 1X 0.0227759
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.0221345
EGLN1 egl-9 family hypoxia-inducible factor 1 0.022044
SNX9 sorting nexin 9 0.0220012
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0217347
KIF5B kinesin family member 5B 0.0217333
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0214064
POTEF POTE ankyrin domain family, member F 0.0212171
MACF1 microtubule-actin crosslinking factor 1 0.0209877
TES testin LIM domain protein 0.0208618
DPY19L1 dpy-19-like 1 (C. elegans) 0.0207532
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.020687
DSCAM Down syndrome cell adhesion molecule 0.020188
YBX1 Y box binding protein 1 0.0201166
PDIA6 protein disulfide isomerase family A, member 6 0.0200583
TMEM41B transmembrane protein 41B 0.0200073
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0199813
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.0199665
KMT2C lysine (K)-specific methyltransferase 2C 0.0196948
NUP58 nucleoporin 58 0.0196706
TOP1 topoisomerase (DNA) I 0.0195764
MYH9 myosin, heavy chain 9, non-muscle 0.0195388
ARL5B ADP-ribosylation factor-like 5B 0.0194428
JUN jun proto-oncogene 0.0193827
MPZL3 myelin protein zero-like 3 0.0193385
SYAP1 synapse associated protein 1 0.0191052
RPL4 ribosomal protein L4 0.0191033
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0190241
RPL26 ribosomal protein L26 0.0190105
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.0189445
DCLK1 doublecortin-like kinase 1 0.0189279
CSNK1A1 casein kinase 1, alpha 1 0.0184628
OSBPL10 oxysterol binding protein-like 10 0.0183107
RAD21 RAD21 homolog (S. pombe) 0.0178561
CPEB2 cytoplasmic polyadenylation element binding protein 2 0.0178304
GPAT3 glycerol-3-phosphate acyltransferase 3 0.0177462
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.017645
CTSB cathepsin B 0.0175409
TOP2B topoisomerase (DNA) II beta 180kDa 0.017349
SLTM SAFB-like, transcription modulator 0.0173412
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0172616
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.01721
RPL23 ribosomal protein L23 0.0171396
CLDND1 claudin domain containing 1 0.0171002
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0169907
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0169609
AGTPBP1 ATP/GTP binding protein 1 0.0169007
SMC3 structural maintenance of chromosomes 3 0.0165505
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.0165015
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0164845
GPX4 glutathione peroxidase 4 0.0163988

decreased expression

Symbol Name Standardized Value
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.175838
FHIT fragile histidine triad -0.15383
RAD51B RAD51 paralog B -0.128096
CD36 CD36 molecule (thrombospondin receptor) -0.119539
FRAS1 Fraser extracellular matrix complex subunit 1 -0.115322
IER3 immediate early response 3 -0.100691
PTMA prothymosin, alpha -0.0961975
RPL35A ribosomal protein L35a -0.0949208
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0883805
RPS6 ribosomal protein S6 -0.0825878
CUX1 cut-like homeobox 1 -0.0812605
CCSER1 coiled-coil serine-rich protein 1 -0.0780728
GPHN gephyrin -0.0753593
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0719367
FLOT1 flotillin 1 -0.0637289
HDAC2 histone deacetylase 2 -0.0611282
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0602441
VCL vinculin -0.0568995
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.05599
TPT1 tumor protein, translationally-controlled 1 -0.052029
RPS29 ribosomal protein S29 -0.0509126
EXOC4 exocyst complex component 4 -0.0505455
RPS23 ribosomal protein S23 -0.0492587
HMGA2 high mobility group AT-hook 2 -0.0480047
RPS24 ribosomal protein S24 -0.0469436
EGR1 early growth response 1 -0.0466558
RPL34 ribosomal protein L34 -0.04542
MTAP methylthioadenosine phosphorylase -0.0446584
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0431977
DIAPH2 diaphanous-related formin 2 -0.0424713
RPS25 ribosomal protein S25 -0.0417735
RPL31 ribosomal protein L31 -0.0393826
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -0.039155
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0390521
PHF14 PHD finger protein 14 -0.0383219
DENND1A DENN/MADD domain containing 1A -0.0381647
PARD3 par-3 family cell polarity regulator -0.0379847
SKAP1 src kinase associated phosphoprotein 1 -0.0376364
TRAF3 TNF receptor-associated factor 3 -0.0373785
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0371484
SLCO1B3-SLCO1B7 SLCO1B3-SLCO1B7 readthrough -0.036236
SMYD3 SET and MYND domain containing 3 -0.0361524
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0358311
PRELID2 PRELI domain containing 2 -0.0353314
IGFBP3 insulin-like growth factor binding protein 3 -0.0343564
RPS13 ribosomal protein S13 -0.0340401
ATP5F1B ATP synthase F1 subunit beta -0.0327005
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0322816
MCU mitochondrial calcium uniporter -0.032055
HLA-B major histocompatibility complex, class I, B -0.0319774
FNDC3B fibronectin type III domain containing 3B -0.0314832
SETD5 SET domain containing 5 -0.0313181
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0310043
ANKRD17 ankyrin repeat domain 17 -0.0308535
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.030643
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0304336
TTC3 tetratricopeptide repeat domain 3 -0.0300108
SBF2 SET binding factor 2 -0.0299892
AOPEP aminopeptidase O (putative) -0.029786
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0297261
EHBP1 EH domain binding protein 1 -0.0296064
BPTF bromodomain PHD finger transcription factor -0.029144
ITGB4 integrin, beta 4 -0.0283992
UBAP2 ubiquitin associated protein 2 -0.0283011
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0278927
PATJ PATJ crumbs cell polarity complex component -0.02778
ZBTB7C zinc finger and BTB domain containing 7C -0.02746
COMMD10 COMM domain containing 10 -0.0272886
RPLP2 ribosomal protein, large, P2 -0.0268894
NF1 neurofibromin 1 -0.0267357
TBC1D5 TBC1 domain family, member 5 -0.0266074
SPIDR scaffolding protein involved in DNA repair -0.0263483
TENM3 teneurin transmembrane protein 3 -0.0255544
RPS8 ribosomal protein S8 -0.0250671
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.025044
KRT18 keratin 18, type I -0.02504
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0246482
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0246124
RPL5 ribosomal protein L5 -0.0245742
THSD4 thrombospondin, type I, domain containing 4 -0.0243636
TMEM123 transmembrane protein 123 -0.0242793
FAF1 Fas (TNFRSF6) associated factor 1 -0.0239838
KANK1 KN motif and ankyrin repeat domains 1 -0.0238989
SERINC5 serine incorporator 5 -0.0238692
GLCCI1 glucocorticoid induced 1 -0.0238209
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0236238
RPS10 ribosomal protein S10 -0.023537
MAML3 mastermind-like 3 (Drosophila) -0.0232617
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.023132
USP34 ubiquitin specific peptidase 34 -0.0229068
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -0.0228853
TAS2R14 taste receptor, type 2, member 14 -0.022707
PTPRG protein tyrosine phosphatase, receptor type, G -0.0224085
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0223686
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0222241
EFNB2 ephrin-B2 -0.0220526
RPL7A ribosomal protein L7a -0.0220318
FTH1 ferritin, heavy polypeptide 1 -0.0218978
HMGA1 high mobility group AT-hook 1 -0.0218587
CCND1 cyclin D1 -0.0217689