Gallic acid_SW480 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in SW480 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
NKD1 naked cuticle homolog 1 (Drosophila) 0.22225
ENO1 enolase 1, (alpha) 0.153248
AHNAK AHNAK nucleoprotein 0.135068
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0855898
ACTG1 actin gamma 1 0.0739398
EEF2 eukaryotic translation elongation factor 2 0.0714983
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0714893
LDHA lactate dehydrogenase A 0.0629901
POTEF POTE ankyrin domain family, member F 0.0620018
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0605272
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0600475
EZR ezrin 0.0572124
EIF4B eukaryotic translation initiation factor 4B 0.0554235
PCBP2 poly(rC) binding protein 2 0.0502727
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0500466
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.046567
RPL4 ribosomal protein L4 0.0462876
TNS3 tensin 3 0.0456027
YAP1 Yes-associated protein 1 0.0441287
IPO7 importin 7 0.0422372
ANXA2 annexin A2 0.0420845
HSPA8 heat shock 70kDa protein 8 0.0417937
DST dystonin 0.0406833
FAT1 FAT atypical cadherin 1 0.0391516
ITGA6 integrin, alpha 6 0.0389565
PTMA prothymosin, alpha 0.0389222
KRT18 keratin 18, type I 0.0383923
LOC102724023 ES1 protein homolog, mitochondrial 0.0377959
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0373115
EIF4A1 eukaryotic translation initiation factor 4A1 0.0365992
SPATA13 spermatogenesis associated 13 0.0365333
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0353003
PGK1 phosphoglycerate kinase 1 0.034672
PLEC plectin 0.0342627
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.0331245
ACTN1 actinin, alpha 1 0.0316096
YBX1 Y box binding protein 1 0.0314061
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0305075
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0301802
MED13 mediator complex subunit 13 0.0300175
SMAD3 SMAD family member 3 0.029497
BZW1 basic leucine zipper and W2 domains 1 0.0292166
KRT8 keratin 8, type II 0.0287625
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0284443
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0278912
CALR calreticulin 0.0277846
APLP2 amyloid beta (A4) precursor-like protein 2 0.0277785
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0277246
FTH1 ferritin, heavy polypeptide 1 0.0271406
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0267179
CSDE1 cold shock domain containing E1, RNA-binding 0.026403
SFPQ splicing factor proline/glutamine-rich 0.026367
RPL3 ribosomal protein L3 0.0263395
DSPP dentin sialophosphoprotein 0.026193
SRRM2 serine/arginine repetitive matrix 2 0.0261515
MYH9 myosin, heavy chain 9, non-muscle 0.0257488
PA2G4 proliferation-associated 2G4, 38kDa 0.0256178
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0255339
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0247683
THRAP3 thyroid hormone receptor associated protein 3 0.024747
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0241046
FBL fibrillarin 0.0240636
PLIN2 perilipin 2 0.0237666
USP9X ubiquitin specific peptidase 9, X-linked 0.0236791
WWOX WW domain containing oxidoreductase 0.0236143
MACF1 microtubule-actin crosslinking factor 1 0.0231797
DIAPH1 diaphanous-related formin 1 0.023138
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 0.0227331
ITPRID2 ITPR interacting domain containing 2 0.0227297
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0224499
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.0222081
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0221808
KLF5 Kruppel-like factor 5 (intestinal) 0.0220168
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0217722
VIM vimentin 0.0216998
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0216407
SAMD4A sterile alpha motif domain containing 4A 0.0215274
TPM4 tropomyosin 4 0.0213039
RPS4X ribosomal protein S4, X-linked 0.0210176
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0208502
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0207659
ANXA3 annexin A3 0.0207464
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0206796
CEMIP cell migration inducing protein, hyaluronan binding 0.0205687
SMC1A structural maintenance of chromosomes 1A 0.0204201
RBBP7 retinoblastoma binding protein 7 0.0203155
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0200122
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 0.0199275
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.0199025
MTCL1 microtubule crosslinking factor 1 0.0196987
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0196642
SQSTM1 sequestosome 1 0.0195346
TPM3 tropomyosin 3 0.019533
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0195248
JUN jun proto-oncogene 0.0194892
TMSB4X thymosin beta 4, X-linked 0.0194786
GLI3 GLI family zinc finger 3 0.0194571
FLNA filamin A, alpha 0.0194022
ZBTB38 zinc finger and BTB domain containing 38 0.0186
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0185739

decreased expression

Symbol Name Standardized Value
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -0.155568
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0905703
RPS6 ribosomal protein S6 -0.0869482
PDE4D phosphodiesterase 4D, cAMP-specific -0.0772013
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0696376
NAV2 neuron navigator 2 -0.0689309
SDK1 sidekick cell adhesion molecule 1 -0.065817
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0563182
ATXN1 ataxin 1 -0.0537587
DIAPH3 diaphanous-related formin 3 -0.0530508
RBM39 RNA binding motif protein 39 -0.0490717
SBF2 SET binding factor 2 -0.0484968
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0472981
TAS2R14 taste receptor, type 2, member 14 -0.0459589
RPS24 ribosomal protein S24 -0.0458989
HMGA1 high mobility group AT-hook 1 -0.0453722
MBD5 methyl-CpG binding domain protein 5 -0.0444054
ESYT2 extended synaptotagmin-like protein 2 -0.0413267
OXR1 oxidation resistance 1 -0.0394671
RPS2 ribosomal protein S2 -0.0385855
ANKRD10 ankyrin repeat domain 10 -0.0376459
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.0371767
NKTR natural killer cell triggering receptor -0.0368982
ANLN anillin, actin binding protein -0.0357633
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0341934
PCCA propionyl CoA carboxylase, alpha polypeptide -0.033969
OSBPL3 oxysterol binding protein-like 3 -0.0334004
THOC2 THO complex 2 -0.0331823
MORF4L2 mortality factor 4 like 2 -0.0323552
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0321451
MAML2 mastermind-like 2 (Drosophila) -0.0315844
KMT2C lysine (K)-specific methyltransferase 2C -0.031216
NF1 neurofibromin 1 -0.0311783
TBC1D22A TBC1 domain family, member 22A -0.0310515
GOLGA4 golgin A4 -0.0308241
RPS13 ribosomal protein S13 -0.0307432
SETD5 SET domain containing 5 -0.0298926
BRWD3 bromodomain and WD repeat domain containing 3 -0.02974
COG5 component of oligomeric golgi complex 5 -0.0295988
USP34 ubiquitin specific peptidase 34 -0.0294821
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0294791
CDK8 cyclin-dependent kinase 8 -0.0294477
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0288562
ZMYND8 zinc finger, MYND-type containing 8 -0.028752
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0283598
SKAP1 src kinase associated phosphoprotein 1 -0.0281817
SMC4 structural maintenance of chromosomes 4 -0.0281428
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0281059
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0280915
VGLL4 vestigial-like family member 4 -0.0278716
RUNX1 runt-related transcription factor 1 -0.0276109
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0274139
MYO1D myosin ID -0.0273296
SNX14 sorting nexin 14 -0.0272537
ZNF292 zinc finger protein 292 -0.0272146
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0270567
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0269279
WDFY2 WD repeat and FYVE domain containing 2 -0.0268974
PROX1 prospero homeobox 1 -0.0268935
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.0266169
KMT2E lysine (K)-specific methyltransferase 2E -0.0265828
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0263115
SCAF11 SR-related CTD-associated factor 11 -0.0262007
CELF1 CUGBP, Elav-like family member 1 -0.0261556
HDAC8 histone deacetylase 8 -0.0260669
CDH13 cadherin 13 -0.025704
NCOR1 nuclear receptor corepressor 1 -0.0256606
FNIP1 folliculin interacting protein 1 -0.025324
KIAA1958 KIAA1958 -0.0253095
ZDHHC20 zinc finger, DHHC-type containing 20 -0.0252741
RPL26 ribosomal protein L26 -0.0251732
WSB1 WD repeat and SOCS box containing 1 -0.0251411
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0251184
PHF21A PHD finger protein 21A -0.0250641
AKAP9 A kinase (PRKA) anchor protein 9 -0.0249947
NDRG1 N-myc downstream regulated 1 -0.0249767
GOLT1B golgi transport 1B -0.0249394
SLC38A2 solute carrier family 38, member 2 -0.0248555
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.024792
MIS18BP1 MIS18 binding protein 1 -0.0247792
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -0.0246086
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0245319
JMJD1C jumonji domain containing 1C -0.024475
TRIO trio Rho guanine nucleotide exchange factor -0.023877
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -0.0236403
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0236147
ZBTB20 zinc finger and BTB domain containing 20 -0.0235338
RPL35A ribosomal protein L35a -0.0233695
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0230018
RPLP2 ribosomal protein, large, P2 -0.0226903
NIPSNAP2 nipsnap homolog 2 -0.0225557
RPS25 ribosomal protein S25 -0.0225519
RPL19 ribosomal protein L19 -0.0225379
RPL38 ribosomal protein L38 -0.022512
YEATS2 YEATS domain containing 2 -0.0224987
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0224712
RPS21 ribosomal protein S21 -0.0224696
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -0.0224578
RPL28 ribosomal protein L28 -0.0224555
RPL32 ribosomal protein L32 -0.0223835