Gallstones Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Solid crystalline precipitates in the BILIARY TRACT, usually formed in the GALLBLADDER, resulting in the condition of CHOLELITHIASIS. Gallstones, derived from the BILE, consist mainly of calcium, cholesterol, or bilirubin. (Experimental Factor Ontology, EFO_0004210)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D042882
Similar Terms
Downloads & Tools

Genes

85 genes/proteins associated with the disease Gallstones from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 2.88009
GNAS GNAS complex locus 2.88009
CCK cholecystokinin 2.88009
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2.88009
TGFB1 transforming growth factor, beta 1 1.45936
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.44681
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.41313
VCAM1 vascular cell adhesion molecule 1 1.38015
FOS FBJ murine osteosarcoma viral oncogene homolog 1.37761
TNF tumor necrosis factor 1.36905
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.36332
DDIT3 DNA-damage-inducible transcript 3 1.33228
NOS3 nitric oxide synthase 3 (endothelial cell) 1.31927
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.30758
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.28027
F2 coagulation factor II (thrombin) 1.26978
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 1.25619
CCL2 chemokine (C-C motif) ligand 2 1.25525
IL1B interleukin 1, beta 1.24275
ALB albumin 1.23392
APOA1 apolipoprotein A-I 1.23392
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.23169
APOE apolipoprotein E 1.23074
PPARG peroxisome proliferator-activated receptor gamma 1.22566
EGR1 early growth response 1 1.22501
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.21567
NR1H4 nuclear receptor subfamily 1, group H, member 4 1.21402
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.2137
IL6 interleukin 6 1.21173
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.20262
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.1977
VEGFA vascular endothelial growth factor A 1.19345
EGFR epidermal growth factor receptor 1.18751
APOB apolipoprotein B 1.1786
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.17563
CFLAR CASP8 and FADD-like apoptosis regulator 1.17268
KRT8 keratin 8, type II 1.16933
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.165
F7 coagulation factor VII (serum prothrombin conversion accelerator) 1.142
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 1.142
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.14132
ATF4 activating transcription factor 4 1.14064
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.13313
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.12703
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.11877
FADS1 fatty acid desaturase 1 1.11536
CAPN2 calpain 2, (m/II) large subunit 1.11081
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1 1.10872
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.10631
PLG plasminogen 1.10631
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 1.10175
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.10069
KLF10 Kruppel-like factor 10 1.09751
DPP4 dipeptidyl-peptidase 4 1.09119
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.09047
FGG fibrinogen gamma chain 1.08337
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 1.08301
PON1 paraoxonase 1 1.07983
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.07947
THRSP thyroid hormone responsive 1.07911
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.07696
HNF4A hepatocyte nuclear factor 4, alpha 1.0734
NOS2 nitric oxide synthase 2, inducible 1.06987
APOA4 apolipoprotein A-IV 1.06952
BAX BCL2-associated X protein 1.06952
MCL1 myeloid cell leukemia 1 1.06698
SREBF1 sterol regulatory element binding transcription factor 1 1.06588
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.06552
JUN jun proto-oncogene 1.06297
PPARA peroxisome proliferator-activated receptor alpha 1.05828
SOD2 superoxide dismutase 2, mitochondrial 1.05461
FASN fatty acid synthase 1.05015
LPL lipoprotein lipase 1.04904
ADORA1 adenosine A1 receptor 1.03864
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.03752
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.02858
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.02559
BCL2 B-cell CLL/lymphoma 2 1.02447
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.0204
OTC ornithine carbamoyltransferase 1.02003
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.01852
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.01776
SUCLG1 succinate-CoA ligase, alpha subunit 1.01663
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.01361
KRT18 keratin 18, type I 1.01324