Gangrene Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A serious and potentially life-threatening condition that arises when a considerable mass of body tissue dies (necrosis). (Human Phenotype Ontology, HP_0100758)
External Link https://www.disgenet.org/browser/0/1/0/C0017086
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Genes

67 genes associated with the disease Gangrene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
ACE angiotensin I converting enzyme
ACR acrosin
ACSS2 acyl-CoA synthetase short-chain family member 2
AGXT alanine-glyoxylate aminotransferase
ALB albumin
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOXE3 arachidonate lipoxygenase 3
BCOR BCL6 corepressor
C4A complement component 4A (Rodgers blood group)
CCR1 chemokine (C-C motif) receptor 1
CD14 CD14 molecule
CD28 CD28 molecule
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40
ERAP1 endoplasmic reticulum aminopeptidase 1
F5 coagulation factor V (proaccelerin, labile factor)
FAS Fas cell surface death receptor
FIP1L1 factor interacting with PAPOLA and CPSF1
HLA-B major histocompatibility complex, class I, B
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
IFI16 interferon, gamma-inducible protein 16
IFT122 intraflagellar transport 122
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL23R interleukin 23 receptor
IL6 interleukin 6
IRF2BP2 interferon regulatory factor 2 binding protein 2
KIF11 kinesin family member 11
KLRC4 killer cell lectin-like receptor subfamily C, member 4
LIPN lipase, family member N
MBL2 mannose-binding lectin (protein C) 2, soluble
MEFV Mediterranean fever
MLX MLX, MAX dimerization protein
NABP1 nucleic acid binding protein 1
NIPAL4 NIPA-like domain containing 4
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUMA1 nuclear mitotic apparatus protein 1
PADI4 peptidyl arginine deiminase, type IV
PLA2G15 phospholipase A2, group XV
PLAU plasminogen activator, urokinase
PML promyelocytic leukemia
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PRTN3 proteinase 3
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RARA retinoic acid receptor, alpha
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5B signal transducer and activator of transcription 5B
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TGM1 transglutaminase 1
TLR4 toll-like receptor 4
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
UBAC2 UBA domain containing 2
VEGFA vascular endothelial growth factor A
ZBTB16 zinc finger and BTB domain containing 16