Gastric Adenocarcinoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A stomach carcinoma that derives_from epithelial cells of glandular origin. (Human Disease Ontology, DOID_3717)
External Link https://www.disgenet.org/browser/0/1/0/C0278701
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Genes

402 genes associated with the disease Gastric Adenocarcinoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACOT1 acyl-CoA thioesterase 1
ACTB actin, beta
ACVR1 activin A receptor, type I
ACVR2A activin A receptor, type IIA
ADRB2 adrenoceptor beta 2, surface
AFP alpha-fetoprotein
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALPG alkaline phosphatase, germ cell
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPTL4 angiopoietin-like 4
ANKRD33 ankyrin repeat domain 33
ANTXR1 anthrax toxin receptor 1
ANXA1 annexin A1
ANXA7 annexin A7
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
AR androgen receptor
ARID1A AT rich interactive domain 1A (SWI-like)
ATM ATM serine/threonine kinase
AXL AXL receptor tyrosine kinase
B2M beta-2-microglobulin
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BMPR1A bone morphogenetic protein receptor, type IA
BMPR1B bone morphogenetic protein receptor, type IB
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD2 bromodomain containing 2
BRD3 bromodomain containing 3
BRDT bromodomain, testis-specific
BRSK1 BR serine/threonine kinase 1
BTLA B and T lymphocyte associated
CA9 carbonic anhydrase IX
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCDC168 coiled-coil domain containing 168
CCNB1 cyclin B1
CCND1 cyclin D1
CCNG2 cyclin G2
CCR7 chemokine (C-C motif) receptor 7
CD163 CD163 molecule
CD24 CD24 molecule
CD247 CD247 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD44 CD44 molecule (Indian blood group)
CD68 CD68 molecule
CD80 CD80 molecule
CD99 CD99 molecule
CDC25A cell division cycle 25A
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDK2 cyclin-dependent kinase 2
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFC1 cripto, FRL-1, cryptic family 1
CGB5 chorionic gonadotropin, beta polypeptide 5
CHGA chromogranin A
CLDN1 claudin 1
CLDN3 claudin 3
CLDN6 claudin 6
CLDN7 claudin 7
CLIC1 chloride intracellular channel 1
CNOT9 CCR4-NOT transcription complex subunit 9
COL18A1 collagen, type XVIII, alpha 1
COL4A1 collagen, type IV, alpha 1
COL5A2 collagen, type V, alpha 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COX2
CREBBP CREB binding protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR6 chemokine (C-X-C motif) receptor 6
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DACT2 dishevelled-binding antagonist of beta-catenin 2
DAPK1 death-associated protein kinase 1
DCLK1 doublecortin-like kinase 1
DICER1 dicer 1, ribonuclease type III
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLK1 delta-like 1 homolog (Drosophila)
DNM1L dynamin 1-like
DOK2 docking protein 2, 56kDa
EBAG9 estrogen receptor binding site associated, antigen, 9
EGFR epidermal growth factor receptor
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EMC6 ER membrane protein complex subunit 6
ENO1 enolase 1, (alpha)
EPAS1 endothelial PAS domain protein 1
EPHA10 EPH receptor A10
EPHA2 EPH receptor A2
EPHA8 EPH receptor A8
EPHB1 EPH receptor B1
EPHB4 EPH receptor B4
EPN3 epsin 3
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC1 excision repair cross-complementation group 1
ERN1 endoplasmic reticulum to nucleus signaling 1
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV4 ets variant 4
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FASN fatty acid synthase
FAT4 FAT atypical cadherin 4
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF2 fibroblast growth factor 2 (basic)
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLT1 fms-related tyrosine kinase 1
FOSL1 FOS-like antigen 1
FOXM1 forkhead box M1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
GAB1 GRB2-associated binding protein 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAL galanin/GMAP prepropeptide
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5
GAST gastrin
GATA3 GATA binding protein 3
GATA4 GATA binding protein 4
GCFC2 GC-rich sequence DNA-binding factor 2
GHSR growth hormone secretagogue receptor
GLI3 GLI family zinc finger 3
GLS glutaminase
GNAS GNAS complex locus
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GPR15 G protein-coupled receptor 15
GPR39 G protein-coupled receptor 39
GRK6 G protein-coupled receptor kinase 6
GRP gastrin-releasing peptide
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
GUCY2C guanylate cyclase 2C
HDAC6 histone deacetylase 6
HDAC8 histone deacetylase 8
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HOXD4 homeobox D4
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPGDS hematopoietic prostaglandin D synthase
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IL10 interleukin 10
IL17A interleukin 17A
IL17F interleukin 17F
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL24 interleukin 24
IL2RA interleukin 2 receptor, alpha
IL6 interleukin 6
ING4 inhibitor of growth family, member 4
INSR insulin receptor
IRF2 interferon regulatory factor 2
ISG20 interferon stimulated exonuclease gene 20kDa
ISL1 ISL LIM homeobox 1
IST1 increased sodium tolerance 1 homolog (yeast)
ITK IL2-inducible T-cell kinase
JAG1 jagged 1
JAK3 Janus kinase 3
JRK Jrk homolog (mouse)
KDR kinase insert domain receptor
KIAA0226L KIAA0226-like
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT17 keratin 17, type I
LATS2 large tumor suppressor kinase 2
LAYN layilin
LECT1 leukocyte cell derived chemotaxin 1
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LIMS1 LIM and senescent cell antigen-like domains 1
LMLN leishmanolysin-like (metallopeptidase M8 family)
LPAR2 lysophosphatidic acid receptor 2
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LTA lymphotoxin alpha
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAP6 microtubule-associated protein 6
MAPK14 mitogen-activated protein kinase 14
MARK1 MAP/microtubule affinity-regulating kinase 1
MATN3 matrilin 3
MCC mutated in colorectal cancers
MCL1 myeloid cell leukemia 1
MCM5 minichromosome maintenance complex component 5
MCM7 minichromosome maintenance complex component 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MED12 mediator complex subunit 12
MET MET proto-oncogene, receptor tyrosine kinase
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MINK1 misshapen-like kinase 1
MLH1 mutL homolog 1
MLKL mixed lineage kinase domain-like
MMP1 matrix metallopeptidase 1
MMP11 matrix metallopeptidase 11
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MSH3 mutS homolog 3
MSLN mesothelin
MSMB microseminoprotein, beta-
MST1 macrophage stimulating 1
MTAP methylthioadenosine phosphorylase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC3A mucin 3A, cell surface associated
MUC6 mucin 6, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYEOV myeloma overexpressed
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCOA1 nuclear receptor coactivator 1
NES nestin
NET1 neuroepithelial cell transforming 1
NOTCH1 notch 1
NOTCH2 notch 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUP35 nucleoporin 35kDa
ORAOV1 oral cancer overexpressed 1
PALB2 partner and localizer of BRCA2
PCNA proliferating cell nuclear antigen
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PGF placental growth factor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAC1 placenta-specific 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLCE1 phospholipase C, epsilon 1
PLCG1 phospholipase C, gamma 1
POLE polymerase (DNA directed), epsilon, catalytic subunit
POTEF POTE ankyrin domain family, member F
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCI protein kinase C, iota
PRKD2 protein kinase D2
PROM1 prominin 1
PRPF31 pre-mRNA processing factor 31
PRPF38B pre-mRNA processing factor 38B
PSCA prostate stem cell antigen
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRF protein tyrosine phosphatase, receptor type, F
RAB1A RAB1A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RBM45 RNA binding motif protein 45
REG1A regenerating islet-derived 1 alpha
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHOA ras homolog family member A
RIN1 Ras and Rab interactor 1
RIOX2 ribosomal oxygenase 2
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPN2 ribophorin II
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RTKN rhotekin
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SBK1 SH3 domain binding kinase 1
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SIRT1 sirtuin 1
SLC12A9 solute carrier family 12, member 9
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNX10 sorting nexin 10
SOX10 SRY (sex determining region Y)-box 10
SOX2 SRY (sex determining region Y)-box 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPEG SPEG complex locus
SPRY2 sprouty homolog 2 (Drosophila)
SQSTM1 sequestosome 1
SRI sorcin
SRSF7 serine/arginine-rich splicing factor 7
SST somatostatin
SSTR3 somatostatin receptor 3
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK26 serine/threonine protein kinase 26
STMN1 stathmin 1
STOM stomatin
STOML2 stomatin (EPB72)-like 2
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TAC1 tachykinin, precursor 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TEX14 testis expressed 14
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLK2 tousled-like kinase 2
TMPRSS13 transmembrane protease, serine 13
TNF tumor necrosis factor
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNK2 tyrosine kinase, non-receptor, 2
TNS4 tensin 4
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TRAF4 TNF receptor-associated factor 4
TRIM15 tripartite motif containing 15
TRIM25 tripartite motif containing 25
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRRAP transformation/transcription domain-associated protein
TSPAN1 tetraspanin 1
TTN titin
TWIST1 twist family bHLH transcription factor 1
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
USP33 ubiquitin specific peptidase 33
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
WDHD1 WD repeat and HMG-box DNA binding protein 1
WEE2 WEE1 homolog 2 (S. pombe)
WRN Werner syndrome, RecQ helicase-like
WWOX WW domain containing oxidoreductase
YAP1 Yes-associated protein 1
ZDHHC2 zinc finger, DHHC-type containing 2
ZEB2 zinc finger E-box binding homeobox 2
ZNRF3 zinc and ring finger 3