Gastric Ulcer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A peptic ulcer of the gastric mucosa. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002990)
External Link https://www.disgenet.org/browser/0/1/0/C0038358
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Genes

132 genes associated with the disease Gastric Ulcer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACE angiotensin I converting enzyme
ACTB actin, beta
ADAM17 ADAM metallopeptidase domain 17
ADM adrenomedullin
ADRB3 adrenoceptor beta 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANXA1 annexin A1
ARID1B AT rich interactive domain 1B (SWI1-like)
BAD BCL2-associated agonist of cell death
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CCK cholecystokinin
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CISD2 CDGSH iron sulfur domain 2
COL18A1 collagen, type XVIII, alpha 1
COX1
COX2
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DMC1 DNA meiotic recombinase 1
EDN1 endothelin 1
EFNA5 ephrin-A5
EGF epidermal growth factor
EPO erythropoietin
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
F13A1 coagulation factor XIII, A1 polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FN1 fibronectin 1
FOXO4 forkhead box O4
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAL galanin/GMAP prepropeptide
GAST gastrin
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GPX1 glutathione peroxidase 1
GSTM1 glutathione S-transferase mu 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HID1 HID1 domain containing
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HNMT histamine N-methyltransferase
HRH3 histamine receptor H3
HSPA9 heat shock 70kDa protein 9 (mortalin)
IAPP islet amyloid polypeptide
IDUA iduronidase, alpha-L-
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL11 interleukin 11
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL23A interleukin 23, alpha subunit p19
IL6 interleukin 6
INS insulin
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
JAG1 jagged 1
KDR kinase insert domain receptor
KLK1 kallikrein 1
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LOC105371045 uncharacterized LOC105371045
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MET MET proto-oncogene, receptor tyrosine kinase
MGLL monoglyceride lipase
MLN motilin
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
NFE2L2 nuclear factor, erythroid 2-like 2
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NRG1 neuregulin 1
NUCB2 nucleobindin 2
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
PGC progastricsin (pepsinogen C)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAU plasminogen activator, urokinase
PLG plasminogen
POTEF POTE ankyrin domain family, member F
PPARG peroxisome proliferator-activated receptor gamma
PSCA prostate stem cell antigen
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBM45 RNA binding motif protein 45
S100A8 S100 calcium binding protein A8
SDC1 syndecan 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SRF serum response factor (c-fos serum response element-binding transcription factor)
SST somatostatin
TAC1 tachykinin, precursor 1
TEK TEK tyrosine kinase, endothelial
TERT telomerase reverse transcriptase
TFF1 trefoil factor 1
TFF2 trefoil factor 2
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TNF tumor necrosis factor
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VGF VGF nerve growth factor inducible
VIP vasoactive intestinal peptide
WFS1 Wolfram syndrome 1 (wolframin)