Gastrinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A neuroendocrine tumor that results_in an overproduction of gastric acid. (Human Disease Ontology, DOID_5577)
Similar Terms
Downloads & Tools

Genes

148 genes co-occuring with the disease Gastrinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
GAST gastrin 3.976
MEN1 multiple endocrine neoplasia I 3.75
SCT secretin 3.432
SST somatostatin 3.337
PPY pancreatic polypeptide 3.084
CHGA chromogranin A 3.084
VIP vasoactive intestinal peptide 2.976
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.921
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 2.914
GCG glucagon 2.74
SSTR2 somatostatin receptor 2 2.566
SYP synaptophysin 2.533
POMC proopiomelanocortin 2.477
SSTR5 somatostatin receptor 5 2.413
ENO2 enolase 2 (gamma, neuronal) 2.383
INS insulin 2.366
DAXX death-domain associated protein 2.348
PRL prolactin 2.279
PTH parathyroid hormone 2.263
HRH2 histamine receptor H2 2.26
SSTR1 somatostatin receptor 1 2.235
NTS neurotensin 2.192
ATRX alpha thalassemia/mental retardation syndrome X-linked 2.144
GHRH growth hormone releasing hormone 2.142
JUND jun D proto-oncogene 2.118
NF1 neurofibromin 1 2.1
GRP gastrin-releasing peptide 2.077
CCKBR cholecystokinin B receptor 2.071
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.061
SSTR4 somatostatin receptor 4 1.963
PTHLH parathyroid hormone-like hormone 1.936
SSTR3 somatostatin receptor 3 1.904
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.838
MLN motilin 1.806
TSC2 tuberous sclerosis 2 1.8
GRPR gastrin-releasing peptide receptor 1.751
GLP1R glucagon-like peptide 1 receptor 1.745
CHGB chromogranin B 1.744
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.744
CDC73 cell division cycle 73 1.743
RET ret proto-oncogene 1.725
CCK cholecystokinin 1.722
SCTR secretin receptor 1.714
FOXN3 forkhead box N3 1.707
IGF1 insulin-like growth factor 1 (somatomedin C) 1.678
GHRL ghrelin/obestatin prepropeptide 1.63
CASR calcium-sensing receptor 1.62
CRH corticotropin releasing hormone 1.619
GIPR gastric inhibitory polypeptide receptor 1.602
CDKN2A cyclin-dependent kinase inhibitor 2A 1.591
CDX2 caudal type homeobox 2 1.542
TP53 tumor protein p53 1.541
NCAM1 neural cell adhesion molecule 1 1.516
MUTYH mutY homolog 1.509
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.503
NMBR neuromedin B receptor 1.496
MGMT O-6-methylguanine-DNA methyltransferase 1.471
BRS3 bombesin-like receptor 3 1.464
TAC1 tachykinin, precursor 1 1.456
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.443
NMB neuromedin B 1.441
SMAD4 SMAD family member 4 1.429
IFNA1 interferon, alpha 1 1.418
ISL1 ISL LIM homeobox 1 1.417
IFNA2 interferon, alpha 2 1.405
IGF2 insulin-like growth factor 2 1.404
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.396
IFNA16 interferon, alpha 16 1.395
IFNA7 interferon, alpha 7 1.395
IFNA10 interferon, alpha 10 1.394
IFNA8 interferon, alpha 8 1.394
IFNA21 interferon, alpha 21 1.394
IFNA14 interferon, alpha 14 1.394
IFNA6 interferon, alpha 6 1.393
IFNA5 interferon, alpha 5 1.392
IFNA13 interferon, alpha 13 1.391
IFNA4 interferon, alpha 4 1.389
IFNA17 interferon, alpha 17 1.376
KMT2A lysine (K)-specific methyltransferase 2A 1.373
TCHP trichoplein, keratin filament binding 1.372
TSC1 tuberous sclerosis 1 1.365
NKX6-3 NK6 homeobox 3 1.36
SNED1 sushi, nidogen and EGF-like domains 1 1.36
DEPDC5 DEP domain containing 5 1.349
HDC histidine decarboxylase 1.345
INSM1 insulinoma-associated 1 1.339
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.336
KRAS Kirsten rat sarcoma viral oncogene homolog 1.331
CCKAR cholecystokinin A receptor 1.33
NR0B1 nuclear receptor subfamily 0, group B, member 1 1.328
PTEN phosphatase and tensin homolog 1.321
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.318
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 1.298
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.282
GNAS GNAS complex locus 1.282
NEUROG3 neurogenin 3 1.279
PDX1 pancreatic and duodenal homeobox 1 1.269
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.269
GAS1 growth arrest-specific 1 1.268
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.255
ALB albumin 1.244
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.241
CORT cortistatin 1.234
GCGR glucagon receptor 1.206
PRMT5 protein arginine methyltransferase 5 1.194
IGF1R insulin-like growth factor 1 receptor 1.192
EGF epidermal growth factor 1.186
CDKN3 cyclin-dependent kinase inhibitor 3 1.179
GIP gastric inhibitory polypeptide 1.17
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.167
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.161
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.159
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.158
GPR101 G protein-coupled receptor 101 1.157
GCM2 glial cells missing homolog 2 (Drosophila) 1.153
IPMK inositol polyphosphate multikinase 1.145
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.144
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.142
CCDC116 coiled-coil domain containing 116 1.142
REN renin 1.127
KMT2C lysine (K)-specific methyltransferase 2C 1.124
SYPL1 synaptophysin-like 1 1.111
GH1 growth hormone 1 1.11
MEA1 male-enhanced antigen 1 1.109
BRCA2 breast cancer 2, early onset 1.103
RBBP5 retinoblastoma binding protein 5 1.102
PAX8 paired box 8 1.101
VIPR1 vasoactive intestinal peptide receptor 1 1.1
IAPP islet amyloid polypeptide 1.094
SETD2 SET domain containing 2 1.078
MLH1 mutL homolog 1 1.074
EGFR epidermal growth factor receptor 1.066
KRT7 keratin 7, type II 1.064
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.061
AIP aryl hydrocarbon receptor interacting protein 1.055
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 1.055
GH2 growth hormone 2 1.043
SYPL2 synaptophysin-like 2 1.038
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.038
NEUROD1 neuronal differentiation 1 1.037
CHEK2 checkpoint kinase 2 1.036
MET MET proto-oncogene, receptor tyrosine kinase 1.027
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.024
ERBB2 erb-b2 receptor tyrosine kinase 2 1.022
TKFC triokinase/FMN cyclase 1.021
TGM2 transglutaminase 2 1.015
COPA coatomer protein complex, subunit alpha 1.006
KRT19 keratin 19, type I 1.003