Gastrulation Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
Description A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. (Gene Ontology, GO_0007369)
External Link https://reactome.org/PathwayBrowser/#/R-HSA-9758941
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Genes

116 proteins participating in the Gastrulation pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ADRM1 adhesion regulating molecule 1
BMP4 bone morphogenetic protein 4
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLDN7 claudin 7
CREBBP CREB binding protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCR4 chemokine (C-X-C motif) receptor 4
DLL1 delta-like 1 (Drosophila)
DLL3 delta-like 3 (Drosophila)
DLX5 distal-less homeobox 5
EOMES eomesodermin
EP300 E1A binding protein p300
EPHA4 EPH receptor A4
FGF2 fibroblast growth factor 2 (basic)
FGF4 fibroblast growth factor 4
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR1 fibroblast growth factor receptor 1
FOXA1 forkhead box A1
FOXA2 forkhead box A2
FOXC1 forkhead box C1
FOXC2 forkhead box C2
FOXF1 forkhead box F1
FOXH1 forkhead box H1
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GBX2 gastrulation brain homeobox 2
GSC goosecoid homeobox
HES7 hes family bHLH transcription factor 7
IHH indian hedgehog
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
LEF1 lymphoid enhancer-binding factor 1
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LHX1 LIM homeobox 1
MAML1 mastermind-like 1 (Drosophila)
MAML2 mastermind-like 2 (Drosophila)
MAML3 mastermind-like 3 (Drosophila)
MAMLD1 mastermind-like domain containing 1
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MIXL1 Mix paired-like homeobox
MSGN1 mesogenin 1
MSX1 msh homeobox 1
MYB v-myb avian myeloblastosis viral oncogene homolog
NANOG Nanog homeobox
NOG noggin
NOTCH1 notch 1
NOTO notochord homeobox
OCLN occludin
OSR1 odd-skipped related transciption factor 1
OTX2 orthodenticle homeobox 2
PAX2 paired box 2
PAX3 paired box 3
PAX6 paired box 6
PAX7 paired box 7
PAX8 paired box 8
POU3F1 POU class 3 homeobox 1
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RIPPLY2 ripply transcriptional repressor 2
SEM1 SEM1 26S proteasome subunit
SHH sonic hedgehog
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SNAI1 snail family zinc finger 1
SNW1 SNW domain containing 1
SOX1 SRY (sex determining region Y)-box 1
SOX17 SRY (sex determining region Y)-box 17
SOX2 SRY (sex determining region Y)-box 2
TBPL2 TATA box binding protein like 2
TBX6 T-box 6
TBXT T-box transcription factor T
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEAD2 TEA domain family member 2
TEAD4 TEA domain family member 4
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TRIM33 tripartite motif containing 33
WNT3A wingless-type MMTV integration site family, member 3A
YAP1 Yes-associated protein 1
ZEB2 zinc finger E-box binding homeobox 2
ZIC1 Zic family member 1
ZIC2 Zic family member 2
ZNF521 zinc finger protein 521