| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gefitinib_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.117486 |
| EGR1 | early growth response 1 | 0.0383508 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0345714 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0303911 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0288957 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0278801 |
| ANXA1 | annexin A1 | 0.0268975 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0247169 |
| RPS6 | ribosomal protein S6 | 0.0238524 |
| INTS6 | integrator complex subunit 6 | 0.0227902 |
| HMGA2 | high mobility group AT-hook 2 | 0.0224004 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0181893 |
| CENPF | centromere protein F, 350/400kDa | 0.0180357 |
| RPL35A | ribosomal protein L35a | 0.0166957 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0156522 |
| BPTF | bromodomain PHD finger transcription factor | 0.0155757 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0155374 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0144822 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0139387 |
| GOLGB1 | golgin B1 | 0.0134723 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0132697 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0132198 |
| HLA-A | major histocompatibility complex, class I, A | 0.0130956 |
| SCFD1 | sec1 family domain containing 1 | 0.0130156 |
| PSEN1 | presenilin 1 | 0.012745 |
| TNPO3 | transportin 3 | 0.0127287 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0124226 |
| GCG | glucagon | 0.012174 |
| BRD2 | bromodomain containing 2 | 0.0121326 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.012098 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0118739 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0118154 |
| FTL | ferritin, light polypeptide | 0.0117858 |
| DUSP16 | dual specificity phosphatase 16 | 0.0114423 |
| IGF2 | insulin-like growth factor 2 | 0.0112651 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0111841 |
| MKI67 | marker of proliferation Ki-67 | 0.0111058 |
| RPL21 | ribosomal protein L21 | 0.0110764 |
| C1S | complement component 1, s subcomponent | 0.0110338 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.010937 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0109333 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0108881 |
| TUT4 | terminal uridylyl transferase 4 | 0.010821 |
| SETD5 | SET domain containing 5 | 0.0104579 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0104355 |
| RPLP0 | ribosomal protein, large, P0 | 0.0103059 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0102602 |
| MEMO1 | mediator of cell motility 1 | 0.010214 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0101043 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.010083 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0100345 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.00979976 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.00978338 |
| ATP13A3 | ATPase type 13A3 | 0.00973109 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.00965387 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0095715 |
| RCC1 | regulator of chromosome condensation 1 | 0.0095703 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.00952203 |
| MYOM1 | myomesin 1 | 0.00938842 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.00934755 |
| NPC1 | Niemann-Pick disease, type C1 | 0.00928478 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0092667 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0092513 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00922276 |
| RPS26 | ribosomal protein S26 | 0.00914562 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.00890052 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.00887913 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00887191 |
| CCN2 | cellular communication network factor 2 | 0.00879896 |
| PRRC2A | proline-rich coiled-coil 2A | 0.00872361 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.00870459 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.00870165 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00869259 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.00866561 |
| SLMAP | sarcolemma associated protein | 0.00862993 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00856951 |
| NUP98 | nucleoporin 98kDa | 0.00855856 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.008538 |
| TTC27 | tetratricopeptide repeat domain 27 | 0.00850222 |
| SERTAD2 | SERTA domain containing 2 | 0.00845762 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00842345 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.00841814 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.00840673 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00839525 |
| KIAA1328 | KIAA1328 | 0.00836856 |
| GTPBP4 | GTP binding protein 4 | 0.00834872 |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 | 0.00833779 |
| PARN | poly(A)-specific ribonuclease | 0.00833197 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.00832626 |
| UBXN4 | UBX domain protein 4 | 0.00823595 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00823423 |
| RLIM | ring finger protein, LIM domain interacting | 0.00818508 |
| PCID2 | PCI domain containing 2 | 0.00807955 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.00801904 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00801835 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.00800999 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00800881 |
| MSR1 | macrophage scavenger receptor 1 | 0.00799236 |
| CEP70 | centrosomal protein 70kDa | 0.00793338 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.00790351 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.17583 |
| TMSB10 | thymosin beta 10 | -0.129667 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0821314 |
| UBC | ubiquitin C | -0.0812485 |
| AHNAK | AHNAK nucleoprotein | -0.0775622 |
| RPS27A | ribosomal protein S27a | -0.077133 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0756347 |
| MMP12 | matrix metallopeptidase 12 | -0.0635174 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0625982 |
| MED13L | mediator complex subunit 13-like | -0.060549 |
| PCDH7 | protocadherin 7 | -0.0603337 |
| PCBP2 | poly(rC) binding protein 2 | -0.0585218 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0582505 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0558526 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0541638 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0489327 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0471846 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0456423 |
| RPL23 | ribosomal protein L23 | -0.0447719 |
| PTMA | prothymosin, alpha | -0.0417258 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0399131 |
| NLGN1 | neuroligin 1 | -0.0390793 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0387081 |
| DST | dystonin | -0.0373109 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0372052 |
| XPO1 | exportin 1 | -0.0348069 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0333978 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0333448 |
| ZNF292 | zinc finger protein 292 | -0.0331316 |
| CANX | calnexin | -0.0326938 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0316473 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0316079 |
| IPO7 | importin 7 | -0.0304474 |
| ENO1 | enolase 1, (alpha) | -0.0303067 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0295877 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0288578 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0288013 |
| NEK7 | NIMA-related kinase 7 | -0.0282781 |
| CALR | calreticulin | -0.0276887 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0274282 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0268869 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0268709 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0266705 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0266302 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0264114 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0261678 |
| STAG2 | stromal antigen 2 | -0.0260943 |
| TPM3 | tropomyosin 3 | -0.0255391 |
| YBX3 | Y box binding protein 3 | -0.0255203 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0253908 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0252974 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0242958 |
| RPLP1 | ribosomal protein, large, P1 | -0.0242701 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0240461 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0239705 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0238613 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.023029 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0230074 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0224009 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0221628 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0220572 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.022004 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0219892 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0218658 |
| YAP1 | Yes-associated protein 1 | -0.0217989 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0217235 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0215123 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0214233 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0212674 |
| CLDN1 | claudin 1 | -0.0212629 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0211718 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0210928 |
| HDLBP | high density lipoprotein binding protein | -0.0210286 |
| YBX1 | Y box binding protein 1 | -0.0209003 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0208593 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0205171 |
| MPG | N-methylpurine-DNA glycosylase | -0.0204067 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0200955 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0200678 |
| RPLP2 | ribosomal protein, large, P2 | -0.0200121 |
| TPI1 | triosephosphate isomerase 1 | -0.0199431 |
| HMGB2 | high mobility group box 2 | -0.0198972 |
| H1-0 | H1.0 linker histone | -0.0197454 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0194473 |
| DTNA | dystrobrevin, alpha | -0.0194026 |
| VCL | vinculin | -0.0191358 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0190106 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.018803 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0187522 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0184562 |
| TMEM123 | transmembrane protein 123 | -0.018253 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0181789 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0180451 |
| RASAL2 | RAS protein activator like 2 | -0.0180071 |
| APP | amyloid beta (A4) precursor protein | -0.0179357 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0177895 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0177549 |
| RPL19 | ribosomal protein L19 | -0.0176633 |
| OGA | O-GlcNAcase | -0.0176225 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0175376 |
