| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gefitinib_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.300981 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.254658 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0942028 |
| ATP13A3 | ATPase type 13A3 | 0.0839874 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0833168 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0791374 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0774725 |
| STC1 | stanniocalcin 1 | 0.0653024 |
| VEGFA | vascular endothelial growth factor A | 0.0535604 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0527569 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0516112 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0507273 |
| LDHA | lactate dehydrogenase A | 0.0481137 |
| MAP1B | microtubule-associated protein 1B | 0.0470483 |
| POSTN | periostin, osteoblast specific factor | 0.0465208 |
| HMGA2 | high mobility group AT-hook 2 | 0.0462575 |
| COL1A2 | collagen, type I, alpha 2 | 0.0430581 |
| MT2A | metallothionein 2A | 0.0403791 |
| LOX | lysyl oxidase | 0.0390703 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0381245 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0368549 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0361673 |
| MSN | moesin | 0.0352754 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0352197 |
| SPAG9 | sperm associated antigen 9 | 0.0346671 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.033564 |
| SMAD3 | SMAD family member 3 | 0.0334066 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0321725 |
| RASA2 | RAS p21 protein activator 2 | 0.0300143 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0288142 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0288001 |
| CLIC4 | chloride intracellular channel 4 | 0.0286469 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0285948 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0280466 |
| MT1X | metallothionein 1X | 0.0277417 |
| GOLGA4 | golgin A4 | 0.0273901 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0270501 |
| VCAN | versican | 0.026995 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0269377 |
| ARRDC3 | arrestin domain containing 3 | 0.0268453 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0267022 |
| VMP1 | vacuole membrane protein 1 | 0.0260313 |
| PTK2 | protein tyrosine kinase 2 | 0.0260232 |
| SQLE | squalene epoxidase | 0.0258689 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0257175 |
| APP | amyloid beta (A4) precursor protein | 0.0254172 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0253057 |
| FNBP1L | formin binding protein 1-like | 0.0251409 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0251058 |
| ANXA2 | annexin A2 | 0.0246188 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0243671 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0242256 |
| CALU | calumenin | 0.0237885 |
| RBM39 | RNA binding motif protein 39 | 0.0237182 |
| CTSB | cathepsin B | 0.0235195 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0233522 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0233108 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0230506 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0228461 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0227209 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0224228 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0223678 |
| MTSS1 | metastasis suppressor 1 | 0.0220308 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0218387 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0217401 |
| KLF6 | Kruppel-like factor 6 | 0.0216372 |
| SDC4 | syndecan 4 | 0.0214818 |
| TNPO1 | transportin 1 | 0.0214204 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0214093 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0212866 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0211159 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0210043 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0209753 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0208519 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0208097 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0206052 |
| OPTN | optineurin | 0.0205866 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0205056 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0204527 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0203948 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0201182 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0201095 |
| ITGAV | integrin, alpha V | 0.0200765 |
| EMP1 | epithelial membrane protein 1 | 0.0200734 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0198328 |
| FOXJ3 | forkhead box J3 | 0.019658 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0195307 |
| SRPK2 | SRSF protein kinase 2 | 0.0194642 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0194601 |
| NKTR | natural killer cell triggering receptor | 0.0191958 |
| NAV2 | neuron navigator 2 | 0.0191652 |
| ARF4 | ADP-ribosylation factor 4 | 0.0191134 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0188428 |
| FAT1 | FAT atypical cadherin 1 | 0.0186516 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0186267 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0186128 |
| LOXL2 | lysyl oxidase-like 2 | 0.0186085 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0184947 |
| DST | dystonin | 0.0183953 |
| AFAP1 | actin filament associated protein 1 | 0.018362 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.233769 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.200784 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.124634 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.101521 |
| CDH13 | cadherin 13 | -0.095064 |
| IER3 | immediate early response 3 | -0.0920956 |
| TMSB10 | thymosin beta 10 | -0.0878195 |
| ENO1 | enolase 1, (alpha) | -0.0804544 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0743501 |
| RPS8 | ribosomal protein S8 | -0.0618507 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0516906 |
| CADM1 | cell adhesion molecule 1 | -0.049869 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0491068 |
| RPS6 | ribosomal protein S6 | -0.0490436 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0466494 |
| RPL35A | ribosomal protein L35a | -0.045971 |
| COL1A1 | collagen, type I, alpha 1 | -0.0439483 |
| S100A9 | S100 calcium binding protein A9 | -0.040701 |
| FTL | ferritin, light polypeptide | -0.0373554 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.036605 |
| RPLP1 | ribosomal protein, large, P1 | -0.0360416 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0354467 |
| ASPH | aspartate beta-hydroxylase | -0.0340417 |
| MTDH | metadherin | -0.0336398 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0334959 |
| RACK1 | receptor for activated C kinase 1 | -0.0332775 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0324686 |
| RPS20 | ribosomal protein S20 | -0.0322083 |
| VIM | vimentin | -0.0316069 |
| RPL23 | ribosomal protein L23 | -0.0304152 |
| RPS19 | ribosomal protein S19 | -0.029755 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0294972 |
| CALR | calreticulin | -0.0293799 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0290021 |
| EGFR | epidermal growth factor receptor | -0.0284502 |
| SQSTM1 | sequestosome 1 | -0.0281145 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0273909 |
| RPL12 | ribosomal protein L12 | -0.0267788 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0267384 |
| RPL37A | ribosomal protein L37a | -0.0266274 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0263051 |
| HLA-B | major histocompatibility complex, class I, B | -0.0250308 |
| PTMA | prothymosin, alpha | -0.0243754 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0235889 |
| RPL19 | ribosomal protein L19 | -0.02299 |
| FAM13A | family with sequence similarity 13, member A | -0.0226959 |
| S100A10 | S100 calcium binding protein A10 | -0.0226792 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0225506 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0220733 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.0212781 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0212541 |
| AHNAK | AHNAK nucleoprotein | -0.0210827 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0209277 |
| RPL26 | ribosomal protein L26 | -0.0206445 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0205487 |
| RPL11 | ribosomal protein L11 | -0.0205281 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0204788 |
| HM13 | histocompatibility (minor) 13 | -0.0202722 |
| RPS3 | ribosomal protein S3 | -0.0197088 |
| RPL36 | ribosomal protein L36 | -0.0194319 |
| RPL9 | ribosomal protein L9 | -0.0190807 |
| NDRG1 | N-myc downstream regulated 1 | -0.018899 |
| RPS5 | ribosomal protein S5 | -0.0185738 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0184648 |
| RPL34 | ribosomal protein L34 | -0.0184081 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0179579 |
| RPL8 | ribosomal protein L8 | -0.0179218 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0178942 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0178363 |
| COL5A1 | collagen, type V, alpha 1 | -0.0176787 |
| RPL5 | ribosomal protein L5 | -0.017524 |
| RPS2 | ribosomal protein S2 | -0.0174988 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0174259 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0173833 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0173062 |
| CMIP | c-Maf inducing protein | -0.0168835 |
| CST3 | cystatin C | -0.0167278 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0166756 |
| RPL13A | ribosomal protein L13a | -0.0166053 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0165289 |
| RPL18 | ribosomal protein L18 | -0.0164587 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0163773 |
| MYDGF | myeloid-derived growth factor | -0.016133 |
| RPL28 | ribosomal protein L28 | -0.01608 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0160252 |
| RPS14 | ribosomal protein S14 | -0.0158641 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0157639 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0157373 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0156047 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0155795 |
| CUX1 | cut-like homeobox 1 | -0.0154496 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0153995 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0152947 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0152502 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0151727 |
| IL6ST | interleukin 6 signal transducer | -0.0151692 |
| LMNA | lamin A/C | -0.0149977 |
| S100A6 | S100 calcium binding protein A6 | -0.0149284 |
| RPL30 | ribosomal protein L30 | -0.0147854 |
| RPS12 | ribosomal protein S12 | -0.0146046 |
