| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gefitinib_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.141974 |
| FN1 | fibronectin 1 | 0.110325 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.10407 |
| DSPP | dentin sialophosphoprotein | 0.0912418 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0806284 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0709219 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0637946 |
| C3 | complement component 3 | 0.0612502 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0608611 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0548869 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0518493 |
| DST | dystonin | 0.0501269 |
| SDC4 | syndecan 4 | 0.0481573 |
| TF | transferrin | 0.045022 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0401544 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.039912 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0397364 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0386287 |
| VEGFA | vascular endothelial growth factor A | 0.036856 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0366789 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0320604 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.030544 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0298515 |
| RBM39 | RNA binding motif protein 39 | 0.0294351 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0293916 |
| LDHA | lactate dehydrogenase A | 0.0293019 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0289629 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0287275 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0279295 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0278871 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0262234 |
| CFB | complement factor B | 0.0262231 |
| VMP1 | vacuole membrane protein 1 | 0.0258536 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0255794 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0253569 |
| RPL3 | ribosomal protein L3 | 0.0252893 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0247815 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0245224 |
| ATXN1 | ataxin 1 | 0.0240536 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0236888 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0235312 |
| AFDN | afadin, adherens junction formation factor | 0.0228394 |
| EHBP1 | EH domain binding protein 1 | 0.0228336 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0223979 |
| ENO1 | enolase 1, (alpha) | 0.0222505 |
| CTSB | cathepsin B | 0.0217069 |
| CPE | carboxypeptidase E | 0.0216179 |
| SVIL | supervillin | 0.0211599 |
| APOB | apolipoprotein B | 0.020905 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0206377 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0201784 |
| OPTN | optineurin | 0.0198243 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.019419 |
| TXNRD1 | thioredoxin reductase 1 | 0.0192198 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0192146 |
| ASPH | aspartate beta-hydroxylase | 0.0189679 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.018805 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0186982 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.018596 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0181754 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0181586 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0181396 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0179081 |
| PCBP2 | poly(rC) binding protein 2 | 0.0178857 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0177443 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0174635 |
| USP34 | ubiquitin specific peptidase 34 | 0.0173307 |
| KIAA1217 | KIAA1217 | 0.0170582 |
| ANXA5 | annexin A5 | 0.0169915 |
| BRD2 | bromodomain containing 2 | 0.0168936 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0168392 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0167786 |
| FLNB | filamin B, beta | 0.0166471 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0164445 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0163912 |
| RTN4 | reticulon 4 | 0.0163761 |
| CLU | clusterin | 0.0162892 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0162146 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0161155 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.0160729 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0160388 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0160062 |
| NUP58 | nucleoporin 58 | 0.0159755 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0159468 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0157738 |
| JMJD1C | jumonji domain containing 1C | 0.0156327 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0156294 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0155387 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0154926 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0154924 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0153715 |
| JAG1 | jagged 1 | 0.0152992 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.015163 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0150401 |
| FRMD5 | FERM domain containing 5 | 0.0150103 |
| WWC2 | WW and C2 domain containing 2 | 0.0149541 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.014953 |
| SKIL | SKI-like proto-oncogene | 0.0149035 |
| PRKCA | protein kinase C, alpha | 0.0148862 |
| KLF6 | Kruppel-like factor 6 | 0.0148574 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0415268 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0393975 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0366298 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0334535 |
| RPL35A | ribosomal protein L35a | -0.0301644 |
| RPLP1 | ribosomal protein, large, P1 | -0.0290939 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0290511 |
| RPS24 | ribosomal protein S24 | -0.02758 |
| TMSB10 | thymosin beta 10 | -0.0275218 |
| FTL | ferritin, light polypeptide | -0.0261052 |
| RPL11 | ribosomal protein L11 | -0.0237454 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0232937 |
| RPL34 | ribosomal protein L34 | -0.0225292 |
| RPS19 | ribosomal protein S19 | -0.0217151 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0203218 |
| GNAS | GNAS complex locus | -0.0198213 |
| AHSG | alpha-2-HS-glycoprotein | -0.0187856 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0168646 |
| RPS8 | ribosomal protein S8 | -0.0167649 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0159977 |
| RPL37 | ribosomal protein L37 | -0.0155016 |
| EGR1 | early growth response 1 | -0.0146634 |
| RPS21 | ribosomal protein S21 | -0.0143262 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0139955 |
| RPS20 | ribosomal protein S20 | -0.013531 |
| RPL19 | ribosomal protein L19 | -0.0133405 |
| GK | glycerol kinase | -0.0129816 |
| RPL38 | ribosomal protein L38 | -0.0129439 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0128412 |
| HMGA1 | high mobility group AT-hook 1 | -0.0128001 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0125439 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0125152 |
| RPS25 | ribosomal protein S25 | -0.0123481 |
| RPS5 | ribosomal protein S5 | -0.0122942 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.012037 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0118867 |
| NPR2 | natriuretic peptide receptor 2 | -0.011681 |
| RPL27A | ribosomal protein L27a | -0.0114649 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.01143 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0111991 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.010918 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0109117 |
| NCOA7 | nuclear receptor coactivator 7 | -0.010849 |
| CCND1 | cyclin D1 | -0.0107395 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.0105626 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0105445 |
| RRBP1 | ribosome binding protein 1 | -0.0105276 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0103013 |
| A2M | alpha-2-macroglobulin | -0.0102642 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0101937 |
| RPL28 | ribosomal protein L28 | -0.00998739 |
| RPL37A | ribosomal protein L37a | -0.00996653 |
| RPS14 | ribosomal protein S14 | -0.00996547 |
| IER3 | immediate early response 3 | -0.00989431 |
| CP | ceruloplasmin (ferroxidase) | -0.00976747 |
| APOA1 | apolipoprotein A-I | -0.00976641 |
| RPS29 | ribosomal protein S29 | -0.00974799 |
| RPS10 | ribosomal protein S10 | -0.0096702 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.00964063 |
| RPS23 | ribosomal protein S23 | -0.00954526 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00954315 |
| RPL35 | ribosomal protein L35 | -0.00946136 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.00940002 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.00937134 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.00906223 |
| RPL23 | ribosomal protein L23 | -0.00901041 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00885578 |
| BPIFB2 | BPI fold containing family B, member 2 | -0.0087376 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00871377 |
| RPL32 | ribosomal protein L32 | -0.00863206 |
| WTAP | Wilms tumor 1 associated protein | -0.0084639 |
| RPS2 | ribosomal protein S2 | -0.00835118 |
| RPL39 | ribosomal protein L39 | -0.00828981 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.00828074 |
| FABP1 | fatty acid binding protein 1, liver | -0.00815218 |
| RPL36 | ribosomal protein L36 | -0.00814271 |
| HMGB1 | high mobility group box 1 | -0.0080787 |
| AHNAK | AHNAK nucleoprotein | -0.00797948 |
| RPL31 | ribosomal protein L31 | -0.0079683 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00792185 |
| CDC27 | cell division cycle 27 | -0.00788355 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.00782431 |
| GDF15 | growth differentiation factor 15 | -0.00777317 |
| APOA2 | apolipoprotein A-II | -0.00776957 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00769944 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00764142 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00761046 |
| ATXN2L | ataxin 2-like | -0.00760581 |
| RPL6 | ribosomal protein L6 | -0.00754955 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.00754428 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0074523 |
| RYBP | RING1 and YY1 binding protein | -0.00744081 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0073735 |
| SEPTIN7 | septin 7 | -0.00735955 |
| RACK1 | receptor for activated C kinase 1 | -0.00730533 |
| RPS27 | ribosomal protein S27 | -0.00728444 |
| RPL8 | ribosomal protein L8 | -0.00726668 |
| RTKN | rhotekin | -0.00726441 |
| RNF24 | ring finger protein 24 | -0.0072257 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00722442 |
