| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gefitinib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | 0.081434 |
| LMO7 | LIM domain 7 | 0.0623995 |
| FOXO1 | forkhead box O1 | 0.0476785 |
| INTS6 | integrator complex subunit 6 | 0.0379426 |
| MSN | moesin | 0.0371622 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0322745 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.029436 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0292598 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0277776 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0275508 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0274929 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0252757 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0221367 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0219361 |
| SEPTIN9 | septin 9 | 0.0210547 |
| TGM2 | transglutaminase 2 | 0.0199653 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0194 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0193318 |
| COG6 | component of oligomeric golgi complex 6 | 0.0192174 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0188024 |
| RBM39 | RNA binding motif protein 39 | 0.0187608 |
| MYOF | myoferlin | 0.018557 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0183955 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0183789 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0182489 |
| SQSTM1 | sequestosome 1 | 0.0181939 |
| GOLGA4 | golgin A4 | 0.0180178 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0179858 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0179117 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0177967 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0174707 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0173466 |
| OSMR | oncostatin M receptor | 0.0173062 |
| SCFD1 | sec1 family domain containing 1 | 0.0171897 |
| USP34 | ubiquitin specific peptidase 34 | 0.0169529 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0168601 |
| STC1 | stanniocalcin 1 | 0.0168482 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0167907 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0167491 |
| SMAD3 | SMAD family member 3 | 0.0167017 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0166179 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.016617 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0165121 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0164562 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0160939 |
| ARRDC3 | arrestin domain containing 3 | 0.0160397 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0160187 |
| CUL4B | cullin 4B | 0.0157192 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0155597 |
| KIF16B | kinesin family member 16B | 0.0155545 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0154475 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0153463 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0152201 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0151423 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0149781 |
| SERINC3 | serine incorporator 3 | 0.0149125 |
| PCDH1 | protocadherin 1 | 0.0148941 |
| RLIM | ring finger protein, LIM domain interacting | 0.0148342 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0146167 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0145457 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0143433 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0141709 |
| EFNA5 | ephrin-A5 | 0.0141632 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0140548 |
| MT1E | metallothionein 1E | 0.0140271 |
| SPAG9 | sperm associated antigen 9 | 0.0139877 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0138685 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.013708 |
| FN1 | fibronectin 1 | 0.0136644 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0135375 |
| CD44 | CD44 molecule (Indian blood group) | 0.0134682 |
| DSCAM | Down syndrome cell adhesion molecule | 0.013334 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0131029 |
| COPA | coatomer protein complex, subunit alpha | 0.0130185 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0130031 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0129965 |
| NUP98 | nucleoporin 98kDa | 0.0128221 |
| PTK2 | protein tyrosine kinase 2 | 0.0128069 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.012768 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0127641 |
| ANO6 | anoctamin 6 | 0.0127157 |
| FNIP1 | folliculin interacting protein 1 | 0.0125946 |
| PRELID2 | PRELI domain containing 2 | 0.0125879 |
| OGA | O-GlcNAcase | 0.0124629 |
| STAG2 | stromal antigen 2 | 0.0124532 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0123061 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0122727 |
| KIF1B | kinesin family member 1B | 0.0122693 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0122106 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0121836 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.012174 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0121635 |
| HLA-E | major histocompatibility complex, class I, E | 0.0119301 |
| RAB10 | RAB10, member RAS oncogene family | 0.0119089 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0119013 |
| NDRG1 | N-myc downstream regulated 1 | 0.0118613 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0117767 |
| DIAPH1 | diaphanous-related formin 1 | 0.0117451 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0116904 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0116702 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.186326 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.112719 |
| PTMA | prothymosin, alpha | -0.108276 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0591701 |
| TMSB10 | thymosin beta 10 | -0.0476506 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0422519 |
| S100A10 | S100 calcium binding protein A10 | -0.0415396 |
| HLA-B | major histocompatibility complex, class I, B | -0.039013 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0376927 |
| RPLP1 | ribosomal protein, large, P1 | -0.0375661 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0368834 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0347894 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0345129 |
| TMSB4X | thymosin beta 4, X-linked | -0.0332388 |
| CAVIN1 | caveolae associated protein 1 | -0.031965 |
| RPL35A | ribosomal protein L35a | -0.0302345 |
| B2M | beta-2-microglobulin | -0.0301223 |
| RPL26 | ribosomal protein L26 | -0.0295564 |
| RPL36A | ribosomal protein L36a | -0.0288037 |
| RPS21 | ribosomal protein S21 | -0.0287049 |
| ACTG1 | actin gamma 1 | -0.0283884 |
| RPS24 | ribosomal protein S24 | -0.0266592 |
| HMGA2 | high mobility group AT-hook 2 | -0.025341 |
| RPS6 | ribosomal protein S6 | -0.0241124 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0236295 |
| IER3 | immediate early response 3 | -0.0229438 |
| RPLP2 | ribosomal protein, large, P2 | -0.0227009 |
| IGF2 | insulin-like growth factor 2 | -0.0224087 |
| RPL8 | ribosomal protein L8 | -0.0217243 |
| PODXL | podocalyxin-like | -0.0217038 |
| RPL12 | ribosomal protein L12 | -0.0212173 |
| SP100 | SP100 nuclear antigen | -0.0212008 |
| RPL31 | ribosomal protein L31 | -0.0211184 |
| RPL34 | ribosomal protein L34 | -0.0210507 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.021027 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0208485 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0208133 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0207796 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0206814 |
| GNAS | GNAS complex locus | -0.0205085 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0204189 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0200078 |
| ANXA2 | annexin A2 | -0.0199721 |
| SEPTIN7 | septin 7 | -0.0199652 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0195069 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0189892 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0188693 |
| CUX1 | cut-like homeobox 1 | -0.0181792 |
| MT2A | metallothionein 2A | -0.0177091 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0176369 |
| RPS25 | ribosomal protein S25 | -0.0168883 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0168485 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0167501 |
| RPS27A | ribosomal protein S27a | -0.0167415 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0167317 |
| BLCAP | bladder cancer associated protein | -0.016682 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0163558 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0162524 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0161082 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0160336 |
| TRIM56 | tripartite motif containing 56 | -0.015843 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0158171 |
| VCL | vinculin | -0.0155948 |
| PGK1 | phosphoglycerate kinase 1 | -0.0154226 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0153533 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0153015 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0150492 |
| H1-0 | H1.0 linker histone | -0.0149329 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0147745 |
| AHNAK | AHNAK nucleoprotein | -0.0147264 |
| YBX1 | Y box binding protein 1 | -0.0145232 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0144283 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0144248 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0143896 |
| LMNA | lamin A/C | -0.0143439 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0143356 |
| PKM | pyruvate kinase, muscle | -0.0141977 |
| IFI44L | interferon-induced protein 44-like | -0.0140971 |
| RND3 | Rho family GTPase 3 | -0.0140096 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0138512 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0135508 |
| RAD51B | RAD51 paralog B | -0.0135018 |
| TMEM165 | transmembrane protein 165 | -0.0134764 |
| TXNRD1 | thioredoxin reductase 1 | -0.0133964 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0133753 |
| RPL35 | ribosomal protein L35 | -0.0133465 |
| COL5A2 | collagen, type V, alpha 2 | -0.0132407 |
| XAF1 | XIAP associated factor 1 | -0.0131625 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0130602 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0130402 |
| RPL36 | ribosomal protein L36 | -0.0130134 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0129584 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0129506 |
| RPL7A | ribosomal protein L7a | -0.0129286 |
| S100A11 | S100 calcium binding protein A11 | -0.0128881 |
| CALR | calreticulin | -0.0127916 |
| NFIA | nuclear factor I/A | -0.0127757 |
| CRACDL | CRACD like | -0.0127519 |
| IFI44 | interferon-induced protein 44 | -0.0127247 |
| RPS27 | ribosomal protein S27 | -0.0126554 |