| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gefitinib_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.1511 |
| TXNRD1 | thioredoxin reductase 1 | 0.108793 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0968134 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0793113 |
| FAM13A | family with sequence similarity 13, member A | 0.0782035 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0760369 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0563566 |
| MYOF | myoferlin | 0.0538423 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0503069 |
| SPAG9 | sperm associated antigen 9 | 0.0480686 |
| LMO7 | LIM domain 7 | 0.0469411 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0452079 |
| ARRDC3 | arrestin domain containing 3 | 0.0422273 |
| RNF145 | ring finger protein 145 | 0.0418978 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0405419 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.040042 |
| OGA | O-GlcNAcase | 0.0375218 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0354655 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0351142 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0327775 |
| TPD52 | tumor protein D52 | 0.0318227 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.030837 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0302103 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0286801 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0276017 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0274116 |
| GRAMD1B | GRAM domain containing 1B | 0.0272096 |
| MKI67 | marker of proliferation Ki-67 | 0.0264409 |
| H1-0 | H1.0 linker histone | 0.0262706 |
| ASPH | aspartate beta-hydroxylase | 0.0257197 |
| UVRAG | UV radiation resistance associated | 0.0256991 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0253426 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0252968 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0251775 |
| TOP1 | topoisomerase (DNA) I | 0.0247653 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.024741 |
| HYOU1 | hypoxia up-regulated 1 | 0.0245009 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0243941 |
| NCKAP1 | NCK-associated protein 1 | 0.0243235 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0240619 |
| CES1 | carboxylesterase 1 | 0.0240439 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0240292 |
| HELZ | helicase with zinc finger | 0.0237695 |
| DSPP | dentin sialophosphoprotein | 0.0222489 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0222477 |
| NGLY1 | N-glycanase 1 | 0.0219803 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0219056 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0217178 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0216546 |
| YBX3 | Y box binding protein 3 | 0.0216532 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0214388 |
| SUCO | SUN domain containing ossification factor | 0.0212855 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.020654 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0204972 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0200375 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0200176 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0194983 |
| PDE8A | phosphodiesterase 8A | 0.0193653 |
| NPTN | neuroplastin | 0.0191551 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0189696 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0186008 |
| NUP58 | nucleoporin 58 | 0.0182045 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0177462 |
| YTHDC1 | YTH domain containing 1 | 0.0177408 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0176977 |
| ATOSA | atos homolog A | 0.0175304 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0174596 |
| SLMAP | sarcolemma associated protein | 0.0172695 |
| HBP1 | HMG-box transcription factor 1 | 0.0172116 |
| WDR45B | WD repeat domain 45B | 0.0171342 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0169648 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0169054 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0168339 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0167032 |
| CCNL1 | cyclin L1 | 0.0166933 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.016276 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0162627 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0162059 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0160272 |
| CDC73 | cell division cycle 73 | 0.0159162 |
| JAK1 | Janus kinase 1 | 0.0158885 |
| PHF21A | PHD finger protein 21A | 0.0158218 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0157679 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0157585 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0157489 |
| ANO6 | anoctamin 6 | 0.0157403 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0157337 |
| EMP1 | epithelial membrane protein 1 | 0.0155965 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0155315 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0155149 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0151533 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0150552 |
| PAPOLA | poly(A) polymerase alpha | 0.0149789 |
| YEATS2 | YEATS domain containing 2 | 0.01496 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0149534 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0149264 |
| RNF24 | ring finger protein 24 | 0.0148948 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0148609 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0146776 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0145843 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.246884 |
| TMSB10 | thymosin beta 10 | -0.156611 |
| EGFR | epidermal growth factor receptor | -0.131817 |
| MT2A | metallothionein 2A | -0.0918986 |
| MCL1 | myeloid cell leukemia 1 | -0.0906528 |
| ACTG1 | actin gamma 1 | -0.0860939 |
| NDRG1 | N-myc downstream regulated 1 | -0.0774895 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0753761 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0750721 |
| EGR1 | early growth response 1 | -0.0734364 |
| RPL35A | ribosomal protein L35a | -0.0689482 |
| S100A10 | S100 calcium binding protein A10 | -0.0615185 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0539982 |
| LAMC2 | laminin, gamma 2 | -0.0537983 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.050528 |
| RPS25 | ribosomal protein S25 | -0.0488295 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0474581 |
| STC1 | stanniocalcin 1 | -0.0470078 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0457058 |
| PTMA | prothymosin, alpha | -0.0442054 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0441357 |
| PKM | pyruvate kinase, muscle | -0.0425362 |
| RPL31 | ribosomal protein L31 | -0.0421916 |
| INTS6 | integrator complex subunit 6 | -0.0415725 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.040962 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0398557 |
| RPS24 | ribosomal protein S24 | -0.0380449 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0379852 |
| RPL37A | ribosomal protein L37a | -0.0375714 |
| RPS8 | ribosomal protein S8 | -0.0374068 |
| CST3 | cystatin C | -0.0366564 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0355441 |
| CDCP1 | CUB domain containing protein 1 | -0.0344135 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0339024 |
| RPS23 | ribosomal protein S23 | -0.0332747 |
| RPS6 | ribosomal protein S6 | -0.0330171 |
| HLA-B | major histocompatibility complex, class I, B | -0.0326193 |
| RPS29 | ribosomal protein S29 | -0.0321447 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0320663 |
| FTL | ferritin, light polypeptide | -0.0319274 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0311149 |
| NABP1 | nucleic acid binding protein 1 | -0.030445 |
| RPL11 | ribosomal protein L11 | -0.0304367 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0304285 |
| RPLP1 | ribosomal protein, large, P1 | -0.0301935 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0299079 |
| HMGA1 | high mobility group AT-hook 1 | -0.0299013 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0298081 |
| PATJ | PATJ crumbs cell polarity complex component | -0.029641 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0293282 |
| S100P | S100 calcium binding protein P | -0.0290487 |
| MYO1D | myosin ID | -0.0289441 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0283025 |
| RPL37 | ribosomal protein L37 | -0.0281333 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0279816 |
| WASF2 | WAS protein family, member 2 | -0.0279581 |
| RPL34 | ribosomal protein L34 | -0.0277383 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0272934 |
| POTEF | POTE ankyrin domain family, member F | -0.0269089 |
| TPM4 | tropomyosin 4 | -0.0267072 |
| RPS3 | ribosomal protein S3 | -0.0264402 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0258143 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0250657 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0250569 |
| RPS27A | ribosomal protein S27a | -0.024958 |
| MYO1E | myosin IE | -0.0247135 |
| RPS12 | ribosomal protein S12 | -0.024573 |
| RPS17 | ribosomal protein S17 | -0.0245714 |
| AREG | amphiregulin | -0.0245166 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0238732 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.023832 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0235513 |
| S100A11 | S100 calcium binding protein A11 | -0.0233702 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.023323 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.022994 |
| ATG7 | autophagy related 7 | -0.0229927 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0226583 |
| FBXO11 | F-box protein 11 | -0.022583 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0224435 |
| KRT18 | keratin 18, type I | -0.0223673 |
| RPS13 | ribosomal protein S13 | -0.022273 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0221198 |
| B2M | beta-2-microglobulin | -0.0217606 |
| MAGEA4 | melanoma antigen family A4 | -0.0215524 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0212988 |
| RPS27 | ribosomal protein S27 | -0.0212648 |
| SP100 | SP100 nuclear antigen | -0.0212035 |
| IER3 | immediate early response 3 | -0.0211206 |
| PDLIM5 | PDZ and LIM domain 5 | -0.020941 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0209226 |
| RPLP2 | ribosomal protein, large, P2 | -0.0208412 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0207873 |
| CSTB | cystatin B (stefin B) | -0.0205817 |
| KRT7 | keratin 7, type II | -0.0204899 |
| RPL30 | ribosomal protein L30 | -0.0203062 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0202443 |
| RPS19 | ribosomal protein S19 | -0.0200199 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0199306 |
| HLA-A | major histocompatibility complex, class I, A | -0.019879 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0194864 |
