| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gefitinib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.0997614 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0814644 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0807883 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0664214 |
| RBM39 | RNA binding motif protein 39 | 0.065009 |
| GOLGA4 | golgin A4 | 0.0589927 |
| USP34 | ubiquitin specific peptidase 34 | 0.0551324 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0501628 |
| PCBP2 | poly(rC) binding protein 2 | 0.0475353 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0461993 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.045699 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0448645 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0429146 |
| SMAD3 | SMAD family member 3 | 0.0417589 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0406757 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0360247 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0353816 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0352632 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0344341 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0338899 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0336253 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0335701 |
| ATP13A3 | ATPase type 13A3 | 0.0331302 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0325338 |
| SPAG9 | sperm associated antigen 9 | 0.0323019 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0310932 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0299059 |
| SIK3 | SIK family kinase 3 | 0.0291077 |
| EFNA5 | ephrin-A5 | 0.027934 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0277364 |
| KYNU | kynureninase | 0.0276729 |
| VMP1 | vacuole membrane protein 1 | 0.0276683 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0269232 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0268131 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0267473 |
| NAV2 | neuron navigator 2 | 0.0261434 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0261055 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0256894 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0256242 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0255458 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0251103 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0248437 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0247736 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0247622 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.024735 |
| FAM107B | family with sequence similarity 107, member B | 0.0243422 |
| RUNX1 | runt-related transcription factor 1 | 0.0242588 |
| OSMR | oncostatin M receptor | 0.0237853 |
| LDHA | lactate dehydrogenase A | 0.023512 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0231067 |
| COPA | coatomer protein complex, subunit alpha | 0.0228237 |
| ANXA2 | annexin A2 | 0.0227416 |
| YME1L1 | YME1-like 1 ATPase | 0.0225437 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0224686 |
| OGA | O-GlcNAcase | 0.0219437 |
| PRRC2C | proline-rich coiled-coil 2C | 0.021704 |
| IL1R1 | interleukin 1 receptor, type I | 0.0216513 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0214534 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0212148 |
| TNNC1 | troponin C type 1 (slow) | 0.0211478 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0208974 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0206424 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0204966 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0204352 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0200631 |
| SEC24A | SEC24 family member A | 0.0196804 |
| ECE1 | endothelin converting enzyme 1 | 0.0196611 |
| COG5 | component of oligomeric golgi complex 5 | 0.0194017 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0193818 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0193701 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0192291 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0192118 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0190859 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.01882 |
| SRP54 | signal recognition particle 54kDa | 0.0187346 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0182848 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0182011 |
| VEGFA | vascular endothelial growth factor A | 0.0181954 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0180466 |
| JMJD1C | jumonji domain containing 1C | 0.0177864 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0177702 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0176463 |
| KIF5B | kinesin family member 5B | 0.0176424 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0175178 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.017498 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0174964 |
| TGM2 | transglutaminase 2 | 0.0174711 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0171737 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0170954 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0170243 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0169943 |
| KLF6 | Kruppel-like factor 6 | 0.0169485 |
| HELZ | helicase with zinc finger | 0.0166193 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0165906 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0165347 |
| FAM13A | family with sequence similarity 13, member A | 0.0163976 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0163688 |
| AHR | aryl hydrocarbon receptor | 0.0163677 |
| SBF2 | SET binding factor 2 | 0.0163604 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0163491 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.061664 |
| CDH13 | cadherin 13 | -0.0440251 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0423977 |
| NRG1 | neuregulin 1 | -0.0360421 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0287899 |
| MEF2A | myocyte enhancer factor 2A | -0.027358 |
| HMGA2 | high mobility group AT-hook 2 | -0.0254005 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0236449 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0235872 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0203745 |
| RPLP1 | ribosomal protein, large, P1 | -0.0194611 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.019172 |
| MECOM | MDS1 and EVI1 complex locus | -0.0187241 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0184739 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.017948 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0177687 |
| ZNF804A | zinc finger protein 804A | -0.0172077 |
| SYT1 | synaptotagmin I | -0.0166919 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0166483 |
| RPL35A | ribosomal protein L35a | -0.0165602 |
| MTSS1 | metastasis suppressor 1 | -0.0162802 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0157009 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0156596 |
| RAI14 | retinoic acid induced 14 | -0.0149305 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0139263 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0138229 |
| FAM20C | family with sequence similarity 20, member C | -0.0134691 |
| SUMF1 | sulfatase modifying factor 1 | -0.0133811 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.013377 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0126777 |
| OXR1 | oxidation resistance 1 | -0.0126613 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0126358 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0125997 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0125993 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0122906 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0121104 |
| ENOSF1 | enolase superfamily member 1 | -0.01199 |
| FBN1 | fibrillin 1 | -0.0118979 |
| RPL34 | ribosomal protein L34 | -0.0115299 |
| CLMP | CXADR-like membrane protein | -0.011518 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.011215 |
| RPS29 | ribosomal protein S29 | -0.0111725 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0110508 |
| DIAPH2 | diaphanous-related formin 2 | -0.0110421 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0110058 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0109713 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0109269 |
| FTL | ferritin, light polypeptide | -0.0108239 |
| RAD51B | RAD51 paralog B | -0.0106269 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0104278 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0103849 |
| AHNAK | AHNAK nucleoprotein | -0.0102883 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0101301 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0100459 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.00993117 |
| CDK14 | cyclin-dependent kinase 14 | -0.00978913 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.00956343 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00951185 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.00945587 |
| ANXA10 | annexin A10 | -0.00945239 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00931664 |
| NAV1 | neuron navigator 1 | -0.00931082 |
| PRRX1 | paired related homeobox 1 | -0.00917297 |
| CMIP | c-Maf inducing protein | -0.00910461 |
| GLIS3 | GLIS family zinc finger 3 | -0.00907721 |
| CFAP96 | cilia and flagella associated protein 96 | -0.00902553 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00896782 |
| COL7A1 | collagen, type VII, alpha 1 | -0.00884657 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.00871521 |
| PRSS23 | protease, serine, 23 | -0.00866721 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00865752 |
| RPS19 | ribosomal protein S19 | -0.00858114 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.00849592 |
| CP | ceruloplasmin (ferroxidase) | -0.00848383 |
| S100A6 | S100 calcium binding protein A6 | -0.00841863 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.00840563 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00830232 |
| FN1 | fibronectin 1 | -0.00814398 |
| DCN | decorin | -0.00807462 |
| MX2 | MX dynamin-like GTPase 2 | -0.00796241 |
| TGFB1 | transforming growth factor, beta 1 | -0.00794614 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.00793143 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00793136 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00788375 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.00786108 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.007812 |
| NAV3 | neuron navigator 3 | -0.00775216 |
| BMERB1 | bMERB domain containing 1 | -0.00770588 |
| RPL31 | ribosomal protein L31 | -0.00768385 |
| PYGL | phosphorylase, glycogen, liver | -0.00767669 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.00765373 |
| CFAP20DC | CFAP20 domain containing | -0.00758922 |
| GLCCI1 | glucocorticoid induced 1 | -0.0075825 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00750148 |
| CUX1 | cut-like homeobox 1 | -0.00748987 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.00747365 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.00736332 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.00731926 |
| RIGI | RNA sensor RIG-I | -0.00727697 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0071755 |
