| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gefitinib_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0709441 |
| WDR43 | WD repeat domain 43 | 0.0666474 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0592799 |
| PUM1 | pumilio RNA-binding family member 1 | 0.058677 |
| TXNRD1 | thioredoxin reductase 1 | 0.0574693 |
| PTK2 | protein tyrosine kinase 2 | 0.0522491 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0515612 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0493898 |
| RBM39 | RNA binding motif protein 39 | 0.0479802 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0478955 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0464608 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0460517 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0441896 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0440071 |
| ERBIN | erbb2 interacting protein | 0.0437077 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0426414 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0424466 |
| FMNL2 | formin-like 2 | 0.0411155 |
| RASAL2 | RAS protein activator like 2 | 0.0410225 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0399258 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.039868 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0394016 |
| RBM25 | RNA binding motif protein 25 | 0.0391814 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0389674 |
| BRD2 | bromodomain containing 2 | 0.0385861 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0381516 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0378728 |
| FLNB | filamin B, beta | 0.0378361 |
| APP | amyloid beta (A4) precursor protein | 0.0371592 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0370044 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0365438 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0354465 |
| TPD52 | tumor protein D52 | 0.0349196 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0345823 |
| CCNL1 | cyclin L1 | 0.0344869 |
| HDAC9 | histone deacetylase 9 | 0.0343698 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0337774 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0328592 |
| COPA | coatomer protein complex, subunit alpha | 0.0322383 |
| ZNF207 | zinc finger protein 207 | 0.031996 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0318266 |
| IGF2 | insulin-like growth factor 2 | 0.0317078 |
| INO80 | INO80 complex subunit | 0.0314372 |
| PARD3 | par-3 family cell polarity regulator | 0.0312945 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0311509 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0308155 |
| SIK3 | SIK family kinase 3 | 0.0305292 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0299466 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0297569 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0296484 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0294557 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0289886 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0289238 |
| YTHDC1 | YTH domain containing 1 | 0.0284605 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0282926 |
| FNBP1L | formin binding protein 1-like | 0.0281805 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0281402 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0277298 |
| LDHA | lactate dehydrogenase A | 0.0275267 |
| USP3 | ubiquitin specific peptidase 3 | 0.0268959 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0268511 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0267764 |
| NUP58 | nucleoporin 58 | 0.026671 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0266562 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0266296 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0262277 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0261594 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0260084 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0258989 |
| PAPOLA | poly(A) polymerase alpha | 0.0257948 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0257624 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.025145 |
| YME1L1 | YME1-like 1 ATPase | 0.024764 |
| GLG1 | golgi glycoprotein 1 | 0.0247578 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0245307 |
| SETD5 | SET domain containing 5 | 0.0243481 |
| RHOA | ras homolog family member A | 0.024254 |
| USP36 | ubiquitin specific peptidase 36 | 0.0238648 |
| KYNU | kynureninase | 0.0235584 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0235173 |
| PLS3 | plastin 3 | 0.0232501 |
| THBS1 | thrombospondin 1 | 0.0232305 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0231478 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0231051 |
| CASC3 | cancer susceptibility candidate 3 | 0.0230773 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.022981 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0228152 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0227083 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0226592 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0225268 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0223445 |
| RNF145 | ring finger protein 145 | 0.0223193 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0223124 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.02222 |
| NOP58 | NOP58 ribonucleoprotein | 0.0221632 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0221027 |
| FGB | fibrinogen beta chain | 0.0219994 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.02196 |
| ANXA1 | annexin A1 | 0.021949 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0218159 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.188891 |
| MT2A | metallothionein 2A | -0.166249 |
| GRAMD1B | GRAM domain containing 1B | -0.112737 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.103364 |
| TMSB10 | thymosin beta 10 | -0.0894659 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0829364 |
| WWOX | WW domain containing oxidoreductase | -0.0570975 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0524788 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0431796 |
| RPLP1 | ribosomal protein, large, P1 | -0.0424829 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0397551 |
| NNMT | nicotinamide N-methyltransferase | -0.0390665 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0386305 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0368575 |
| RPL23 | ribosomal protein L23 | -0.0360611 |
| RPL35A | ribosomal protein L35a | -0.0350916 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0344895 |
| RPS21 | ribosomal protein S21 | -0.0342918 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0335902 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0308002 |
| RPS8 | ribosomal protein S8 | -0.0304437 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0301932 |
| OSMR | oncostatin M receptor | -0.0301427 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0296576 |
| RPS24 | ribosomal protein S24 | -0.0262058 |
| VIM | vimentin | -0.0255388 |
| IER3 | immediate early response 3 | -0.0251924 |
| RPS19 | ribosomal protein S19 | -0.0240434 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0238138 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0232523 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0221797 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0217484 |
| RPS20 | ribosomal protein S20 | -0.021163 |
| RPL9 | ribosomal protein L9 | -0.0208972 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0206185 |
| ATXN1 | ataxin 1 | -0.0200933 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0191836 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0188614 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0187912 |
| HMGB1 | high mobility group box 1 | -0.0184683 |
| RAD51B | RAD51 paralog B | -0.0184473 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0184262 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0183539 |
| RPL30 | ribosomal protein L30 | -0.0182797 |
| ACTG1 | actin gamma 1 | -0.0176178 |
| RPL36 | ribosomal protein L36 | -0.0175976 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.017472 |
| RPL19 | ribosomal protein L19 | -0.0173532 |
| IL6 | interleukin 6 | -0.0168301 |
| RPL38 | ribosomal protein L38 | -0.0167987 |
| S100A10 | S100 calcium binding protein A10 | -0.0166773 |
| FHIT | fragile histidine triad | -0.0166566 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0166288 |
| RPS5 | ribosomal protein S5 | -0.0165072 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0161579 |
| RPS29 | ribosomal protein S29 | -0.01599 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.015929 |
| PDE10A | phosphodiesterase 10A | -0.015659 |
| RPL26 | ribosomal protein L26 | -0.0153631 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0151252 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0150556 |
| RSPO3 | R-spondin 3 | -0.0148807 |
| NHSL1 | NHS-like 1 | -0.0148727 |
| ATP11A | ATPase, class VI, type 11A | -0.0144109 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0143539 |
| RPL34 | ribosomal protein L34 | -0.0140717 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0138774 |
| RPL4 | ribosomal protein L4 | -0.0138441 |
| TUBA1B | tubulin, alpha 1b | -0.0138046 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.0136656 |
| RPL28 | ribosomal protein L28 | -0.0136638 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.013629 |
| S100A6 | S100 calcium binding protein A6 | -0.0135884 |
| RPL12 | ribosomal protein L12 | -0.0135369 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0135084 |
| RPS16 | ribosomal protein S16 | -0.013371 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0133509 |
| WDR59 | WD repeat domain 59 | -0.012991 |
| RPL36A | ribosomal protein L36a | -0.0129598 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0128853 |
| RPL27 | ribosomal protein L27 | -0.0128029 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0128007 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0126856 |
| RPS12 | ribosomal protein S12 | -0.0126547 |
| BMP6 | bone morphogenetic protein 6 | -0.0124571 |
| PRDX1 | peroxiredoxin 1 | -0.012411 |
| BMP5 | bone morphogenetic protein 5 | -0.0123413 |
| FTL | ferritin, light polypeptide | -0.0121989 |
| TUBB | tubulin, beta class I | -0.0120712 |
| PFKP | phosphofructokinase, platelet | -0.0118749 |
| RPS17 | ribosomal protein S17 | -0.0118444 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.011813 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0117546 |
| RPL37 | ribosomal protein L37 | -0.0116719 |
| CLIC1 | chloride intracellular channel 1 | -0.0116425 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0115674 |
| S100A11 | S100 calcium binding protein A11 | -0.0115496 |
| ATF5 | activating transcription factor 5 | -0.0115034 |
| EPGN | epithelial mitogen | -0.0112975 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.011271 |
