| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gefitinib_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.114478 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0995265 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0990806 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0950566 |
| TJP1 | tight junction protein 1 | 0.0934962 |
| ZNF292 | zinc finger protein 292 | 0.0898761 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0894355 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0877393 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0870342 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0856942 |
| VMP1 | vacuole membrane protein 1 | 0.0849305 |
| MXI1 | MAX interactor 1, dimerization protein | 0.084534 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0826023 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0824391 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0748442 |
| FAM13A | family with sequence similarity 13, member A | 0.0742722 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0736618 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0727929 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0714794 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0700092 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.067389 |
| RORA | RAR-related orphan receptor A | 0.0632647 |
| APP | amyloid beta (A4) precursor protein | 0.0630205 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0626135 |
| PRKCA | protein kinase C, alpha | 0.061611 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0610314 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.061026 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0590333 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0586027 |
| TCF12 | transcription factor 12 | 0.0583806 |
| STC1 | stanniocalcin 1 | 0.0574312 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0572331 |
| SETD5 | SET domain containing 5 | 0.0565674 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0562111 |
| CDK13 | cyclin-dependent kinase 13 | 0.0546158 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0543817 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0543742 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0537067 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0535776 |
| EFNA5 | ephrin-A5 | 0.0534253 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0533284 |
| LAMA4 | laminin, alpha 4 | 0.053286 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0532691 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0532633 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0525889 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0521973 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0518053 |
| SEC24D | SEC24 family member D | 0.0517741 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.051527 |
| RLF | rearranged L-myc fusion | 0.0498765 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0498497 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0497905 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0486612 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0479729 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0479125 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0467336 |
| NOP58 | NOP58 ribonucleoprotein | 0.0466796 |
| FUS | FUS RNA binding protein | 0.0464455 |
| FAT1 | FAT atypical cadherin 1 | 0.0463662 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0461895 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0460803 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0443942 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0443318 |
| NEK7 | NIMA-related kinase 7 | 0.0442166 |
| TPR | translocated promoter region, nuclear basket protein | 0.0427437 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0426528 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0425755 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0425078 |
| CTBP2 | C-terminal binding protein 2 | 0.0422256 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0420791 |
| STK24 | serine/threonine kinase 24 | 0.0418441 |
| ERBIN | erbb2 interacting protein | 0.0417888 |
| HDLBP | high density lipoprotein binding protein | 0.0417587 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0417129 |
| FMNL2 | formin-like 2 | 0.0415888 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0405839 |
| SLTM | SAFB-like, transcription modulator | 0.0403526 |
| NBAS | neuroblastoma amplified sequence | 0.0397019 |
| XPO1 | exportin 1 | 0.0396219 |
| FN1 | fibronectin 1 | 0.0390776 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0386074 |
| RBM25 | RNA binding motif protein 25 | 0.0380772 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0380573 |
| QKI | QKI, KH domain containing, RNA binding | 0.0380085 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0380072 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0376373 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0375308 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0375161 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0374388 |
| MED13 | mediator complex subunit 13 | 0.0371747 |
| SMYD3 | SET and MYND domain containing 3 | 0.0364992 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0361967 |
| SUCO | SUN domain containing ossification factor | 0.0361137 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0357841 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0357588 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0352855 |
| ETNK1 | ethanolamine kinase 1 | 0.0351106 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0350588 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0347155 |
| FOSL1 | FOS-like antigen 1 | 0.0345774 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.202124 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.158851 |
| KRT17 | keratin 17, type I | -0.155318 |
| FTL | ferritin, light polypeptide | -0.153757 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.151597 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.107125 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0999518 |
| UBC | ubiquitin C | -0.0965234 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0899755 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0896903 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0799851 |
| PTMA | prothymosin, alpha | -0.0792256 |
| ANXA1 | annexin A1 | -0.0755882 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0733389 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0729016 |
| IER3 | immediate early response 3 | -0.0725292 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0715519 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0708969 |
| SRPK2 | SRSF protein kinase 2 | -0.0680381 |
| S100A9 | S100 calcium binding protein A9 | -0.0676324 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0675681 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0660016 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0656798 |
| S100A6 | S100 calcium binding protein A6 | -0.0645694 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0641928 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0639793 |
| TMSB10 | thymosin beta 10 | -0.0639723 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0638707 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0609283 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0608806 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0598605 |
| CLTC | clathrin, heavy chain (Hc) | -0.0598166 |
| S100A10 | S100 calcium binding protein A10 | -0.0589432 |
| PHF21A | PHD finger protein 21A | -0.058195 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0580244 |
| PNN | pinin, desmosome associated protein | -0.0571395 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0570092 |
| ASPH | aspartate beta-hydroxylase | -0.0561385 |
| LAMB3 | laminin, beta 3 | -0.0558906 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0552688 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0550971 |
| RPL11 | ribosomal protein L11 | -0.0545102 |
| NKTR | natural killer cell triggering receptor | -0.053322 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0518502 |
| MXD1 | MAX dimerization protein 1 | -0.0494467 |
| RPS11 | ribosomal protein S11 | -0.0494171 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0493928 |
| POTEF | POTE ankyrin domain family, member F | -0.0493475 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0484624 |
| RPLP1 | ribosomal protein, large, P1 | -0.0473663 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0473135 |
| RPL19 | ribosomal protein L19 | -0.0471986 |
| JUN | jun proto-oncogene | -0.0470118 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0461412 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0452737 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0452131 |
| SPAG9 | sperm associated antigen 9 | -0.0450828 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0450515 |
| TOP1 | topoisomerase (DNA) I | -0.0449617 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0445966 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0437142 |
| SYT1 | synaptotagmin I | -0.0436065 |
| CD44 | CD44 molecule (Indian blood group) | -0.0431444 |
| PGK1 | phosphoglycerate kinase 1 | -0.0430232 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0422826 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0411267 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0403532 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0399549 |
| FAM107B | family with sequence similarity 107, member B | -0.0399376 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0397357 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0396449 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0395383 |
| TMEM123 | transmembrane protein 123 | -0.03949 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0393283 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0392012 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0383553 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0374949 |
| FNDC3A | fibronectin type III domain containing 3A | -0.037041 |
| SEPTIN2 | septin 2 | -0.0370077 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | -0.0369402 |
| GPATCH2L | G patch domain containing 2-like | -0.0368605 |
| CALR | calreticulin | -0.0364412 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0362612 |
| CCNI | cyclin I | -0.0359597 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0359455 |
| MYO1E | myosin IE | -0.0358754 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0356915 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0355981 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.035567 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0354664 |
| RPL23 | ribosomal protein L23 | -0.0353375 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0351657 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0348879 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0347924 |
| SRGN | serglycin | -0.034367 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0342941 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0342684 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0340492 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.033782 |
| CD2AP | CD2-associated protein | -0.0337188 |
