| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gefitinib_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.157628 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.133087 |
| TXNRD1 | thioredoxin reductase 1 | 0.131884 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.117198 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.100852 |
| COPA | coatomer protein complex, subunit alpha | 0.0891053 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0859032 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0815015 |
| RAD51B | RAD51 paralog B | 0.0675426 |
| LDHA | lactate dehydrogenase A | 0.0638255 |
| PTK2 | protein tyrosine kinase 2 | 0.0610368 |
| EGR1 | early growth response 1 | 0.0607851 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0604631 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0582381 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0581297 |
| RLIM | ring finger protein, LIM domain interacting | 0.0533224 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0528961 |
| H1-0 | H1.0 linker histone | 0.0518449 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0511801 |
| USP34 | ubiquitin specific peptidase 34 | 0.0510453 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.04961 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0481146 |
| DIDO1 | death inducer-obliterator 1 | 0.0479947 |
| KLF6 | Kruppel-like factor 6 | 0.0478073 |
| CCNL1 | cyclin L1 | 0.047106 |
| JMJD1C | jumonji domain containing 1C | 0.0445061 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0442457 |
| RBM39 | RNA binding motif protein 39 | 0.0440599 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0439919 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0438794 |
| JUN | jun proto-oncogene | 0.0435914 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0431465 |
| VMP1 | vacuole membrane protein 1 | 0.0428828 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0423322 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0420152 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0418603 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0415386 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0413439 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0411149 |
| WASF2 | WAS protein family, member 2 | 0.0409358 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0408839 |
| EGFR | epidermal growth factor receptor | 0.0404497 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0403172 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0402679 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0392437 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0390168 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0385299 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0376888 |
| ATP13A3 | ATPase type 13A3 | 0.0375694 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0373673 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0373 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0369185 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0367803 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0363473 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0362494 |
| ACTN1 | actinin, alpha 1 | 0.0362226 |
| PLS3 | plastin 3 | 0.036211 |
| ENO1 | enolase 1, (alpha) | 0.0356473 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0351776 |
| VIM | vimentin | 0.0349522 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0345227 |
| DENND1A | DENN/MADD domain containing 1A | 0.0344026 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0340713 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0334637 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.03335 |
| RPS4X | ribosomal protein S4, X-linked | 0.0333391 |
| SERINC3 | serine incorporator 3 | 0.0333348 |
| SMAD3 | SMAD family member 3 | 0.0325419 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.0324022 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0323298 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0319788 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0318293 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0315733 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0314877 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0311521 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0310432 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | 0.030993 |
| NABP1 | nucleic acid binding protein 1 | 0.030916 |
| FMNL2 | formin-like 2 | 0.0308541 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0306134 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0304907 |
| LATS2 | large tumor suppressor kinase 2 | 0.0304409 |
| UBC | ubiquitin C | 0.0303843 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0301702 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0301256 |
| RNF213 | ring finger protein 213 | 0.0299523 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.029873 |
| RASAL2 | RAS protein activator like 2 | 0.0298659 |
| FLNB | filamin B, beta | 0.0297608 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0296498 |
| NF1 | neurofibromin 1 | 0.0296336 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0295932 |
| WRN | Werner syndrome, RecQ helicase-like | 0.02959 |
| GPHN | gephyrin | 0.0295511 |
| MSN | moesin | 0.0293371 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0292762 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0291321 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0290652 |
| NUP153 | nucleoporin 153kDa | 0.0290406 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0289389 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.213437 |
| YBX3 | Y box binding protein 3 | -0.11554 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0850597 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0774346 |
| GRAMD1B | GRAM domain containing 1B | -0.0747911 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0689108 |
| RPS2 | ribosomal protein S2 | -0.0577494 |
| RPL38 | ribosomal protein L38 | -0.0548721 |
| RPLP1 | ribosomal protein, large, P1 | -0.053756 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0531464 |
| CTTN | cortactin | -0.0442277 |
| RPS29 | ribosomal protein S29 | -0.0440272 |
| TMSB10 | thymosin beta 10 | -0.0417785 |
| RPS21 | ribosomal protein S21 | -0.0409269 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0400411 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0393496 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0379338 |
| RPL9 | ribosomal protein L9 | -0.0372796 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0357196 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0345824 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0342705 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.033531 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.033396 |
| PHF3 | PHD finger protein 3 | -0.0322079 |
| SEPTIN7 | septin 7 | -0.0316224 |
| RPS19 | ribosomal protein S19 | -0.0313927 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0309627 |
| RPS6 | ribosomal protein S6 | -0.0304527 |
| RPS12 | ribosomal protein S12 | -0.0303382 |
| PTMA | prothymosin, alpha | -0.0297415 |
| WWOX | WW domain containing oxidoreductase | -0.0294117 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0291476 |
| XPO1 | exportin 1 | -0.0290151 |
| RPL12 | ribosomal protein L12 | -0.0284762 |
| RPS8 | ribosomal protein S8 | -0.0279994 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0273817 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0273673 |
| RRM2 | ribonucleotide reductase M2 | -0.0267386 |
| RPS15 | ribosomal protein S15 | -0.0267142 |
| NLGN1 | neuroligin 1 | -0.0264991 |
| RPL6 | ribosomal protein L6 | -0.0263765 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0262146 |
| CEP192 | centrosomal protein 192kDa | -0.0261063 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0256266 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0252925 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0251861 |
| RPL27 | ribosomal protein L27 | -0.0250282 |
| TPI1 | triosephosphate isomerase 1 | -0.0250178 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0250058 |
| HBP1 | HMG-box transcription factor 1 | -0.0249994 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0249082 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0248131 |
| MIS18BP1 | MIS18 binding protein 1 | -0.024784 |
| DENR | density-regulated protein | -0.0245393 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0244891 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0243797 |
| STK4 | serine/threonine kinase 4 | -0.0241544 |
| NEMF | nuclear export mediator factor | -0.0240172 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.02337 |
| RPLP2 | ribosomal protein, large, P2 | -0.0229422 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0228893 |
| RPL37A | ribosomal protein L37a | -0.022695 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0226186 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.022549 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0222859 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0219855 |
| RPL7A | ribosomal protein L7a | -0.0216701 |
| ETV6 | ets variant 6 | -0.0216373 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0215052 |
| BMERB1 | bMERB domain containing 1 | -0.0214946 |
| RPL30 | ribosomal protein L30 | -0.0214368 |
| RPS10 | ribosomal protein S10 | -0.0214081 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | -0.021324 |
| RPL37 | ribosomal protein L37 | -0.0212413 |
| ETNK1 | ethanolamine kinase 1 | -0.0212129 |
| APAF1 | apoptotic peptidase activating factor 1 | -0.0211205 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0210966 |
| CCND2 | cyclin D2 | -0.0210956 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0210251 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0208462 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | -0.0207498 |
| MKI67 | marker of proliferation Ki-67 | -0.0207414 |
| TFRC | transferrin receptor | -0.0207121 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0206251 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0203503 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.0203277 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0201317 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.020101 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0200039 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0199312 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.019922 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0199002 |
| IGF2 | insulin-like growth factor 2 | -0.019871 |
| GOLT1B | golgi transport 1B | -0.0197168 |
| QKI | QKI, KH domain containing, RNA binding | -0.0195862 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0193904 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.019319 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0192794 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0192728 |
| STYK1 | serine/threonine/tyrosine kinase 1 | -0.0192648 |
