| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gefitinib_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.0599347 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0500883 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0490473 |
| DST | dystonin | 0.0413921 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.039275 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0351407 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0328188 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0304717 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0288367 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0255657 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0242474 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0239957 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0233148 |
| FLNB | filamin B, beta | 0.0223487 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0222311 |
| NEK7 | NIMA-related kinase 7 | 0.0221523 |
| OGA | O-GlcNAcase | 0.0220752 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0204178 |
| VCL | vinculin | 0.0183887 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0181957 |
| KYNU | kynureninase | 0.0180445 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0178583 |
| INTS6 | integrator complex subunit 6 | 0.0175903 |
| ANXA1 | annexin A1 | 0.0158656 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0157949 |
| LDHA | lactate dehydrogenase A | 0.0157821 |
| RPL3 | ribosomal protein L3 | 0.0156193 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0154815 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0153121 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.014833 |
| WDR43 | WD repeat domain 43 | 0.0148103 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0146098 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0144502 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0143729 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0141149 |
| ASPH | aspartate beta-hydroxylase | 0.0140641 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0138667 |
| CTSC | cathepsin C | 0.0137813 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.013602 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0135811 |
| NCKAP1 | NCK-associated protein 1 | 0.0134084 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0133918 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.013305 |
| MSN | moesin | 0.0132352 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0129633 |
| RTN4 | reticulon 4 | 0.0126683 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0120777 |
| RUNX1 | runt-related transcription factor 1 | 0.0118854 |
| SFPQ | splicing factor proline/glutamine-rich | 0.011792 |
| ATP13A3 | ATPase type 13A3 | 0.0115953 |
| HYOU1 | hypoxia up-regulated 1 | 0.0115897 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0115511 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0113521 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0110983 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0110835 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0109652 |
| RLIM | ring finger protein, LIM domain interacting | 0.0108536 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0108461 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0108434 |
| CDC73 | cell division cycle 73 | 0.0106864 |
| USP53 | ubiquitin specific peptidase 53 | 0.0105157 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0104738 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0104162 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0103856 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0103121 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0103023 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0098374 |
| RNF145 | ring finger protein 145 | 0.00975929 |
| PUM2 | pumilio RNA-binding family member 2 | 0.00973928 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.00972977 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.00964526 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00956949 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.00950415 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.00933367 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00932867 |
| SPOPL | speckle-type POZ protein-like | 0.00932833 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00920483 |
| NUP58 | nucleoporin 58 | 0.00920013 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.00919846 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.00919641 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.00895997 |
| COG5 | component of oligomeric golgi complex 5 | 0.00893994 |
| CUL3 | cullin 3 | 0.00873303 |
| PLCB4 | phospholipase C, beta 4 | 0.00868132 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.00863035 |
| HELZ | helicase with zinc finger | 0.00857061 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.00852921 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0085136 |
| EZR | ezrin | 0.00849799 |
| PTEN | phosphatase and tensin homolog | 0.00843145 |
| RBM33 | RNA binding motif protein 33 | 0.00839865 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00828321 |
| CLU | clusterin | 0.0082683 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.00826587 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.00826 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.00825458 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.00820566 |
| NBAS | neuroblastoma amplified sequence | 0.00810579 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00801605 |
| CASC3 | cancer susceptibility candidate 3 | 0.00800538 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.200994 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.161859 |
| VIM | vimentin | -0.102482 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0993525 |
| TMSB10 | thymosin beta 10 | -0.0883678 |
| COL5A2 | collagen, type V, alpha 2 | -0.070176 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0687428 |
| RPLP1 | ribosomal protein, large, P1 | -0.0646208 |
| RPS6 | ribosomal protein S6 | -0.0587391 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0568128 |
| RPL35A | ribosomal protein L35a | -0.0565463 |
| FN1 | fibronectin 1 | -0.0547956 |
| RPS24 | ribosomal protein S24 | -0.0514172 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0467353 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0457299 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0456942 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0442206 |
| PTMA | prothymosin, alpha | -0.043916 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0413899 |
| RPL37A | ribosomal protein L37a | -0.0410223 |
| RPS8 | ribosomal protein S8 | -0.0409362 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0408357 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0408252 |
| FTL | ferritin, light polypeptide | -0.0407937 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0402221 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0391548 |
| RPL31 | ribosomal protein L31 | -0.0390457 |
| RPL36A | ribosomal protein L36a | -0.0386988 |
| S100A6 | S100 calcium binding protein A6 | -0.0382476 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0373944 |
| RPS19 | ribosomal protein S19 | -0.0371034 |
| HLA-B | major histocompatibility complex, class I, B | -0.0370101 |
| RPLP0 | ribosomal protein, large, P0 | -0.0367928 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0366322 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0365046 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0359526 |
| RPL9 | ribosomal protein L9 | -0.0355532 |
| CDH13 | cadherin 13 | -0.0340997 |
| RPS12 | ribosomal protein S12 | -0.0334857 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0330773 |
| RPL26 | ribosomal protein L26 | -0.0327047 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0322277 |
| RPL34 | ribosomal protein L34 | -0.0320447 |
| RPL12 | ribosomal protein L12 | -0.0315906 |
| RPS21 | ribosomal protein S21 | -0.0313031 |
| HLA-A | major histocompatibility complex, class I, A | -0.0312025 |
| B2M | beta-2-microglobulin | -0.0311992 |
| RPS23 | ribosomal protein S23 | -0.0297393 |
| RPL7A | ribosomal protein L7a | -0.0282083 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0280516 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0279677 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0276551 |
| RPL37 | ribosomal protein L37 | -0.0276507 |
| CTSL | cathepsin L | -0.0274685 |
| GNAS | GNAS complex locus | -0.0271977 |
| RPL38 | ribosomal protein L38 | -0.0268436 |
| RPS14 | ribosomal protein S14 | -0.0264158 |
| RPLP2 | ribosomal protein, large, P2 | -0.0264031 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0263997 |
| RPL19 | ribosomal protein L19 | -0.0260045 |
| IL6 | interleukin 6 | -0.0256774 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0252449 |
| LSAMP | limbic system-associated membrane protein | -0.025031 |
| SMYD3 | SET and MYND domain containing 3 | -0.0248339 |
| LMNA | lamin A/C | -0.0245827 |
| MAP7 | microtubule-associated protein 7 | -0.023405 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0233409 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0233335 |
| PRSS23 | protease, serine, 23 | -0.0232855 |
| RPS16 | ribosomal protein S16 | -0.0231361 |
| RPL11 | ribosomal protein L11 | -0.0229346 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.022663 |
| RPS27 | ribosomal protein S27 | -0.0224913 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0224353 |
| RPS29 | ribosomal protein S29 | -0.0224282 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0221593 |
| RPS27A | ribosomal protein S27a | -0.0221385 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0220009 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0218732 |
| PRKD3 | protein kinase D3 | -0.0215614 |
| RPS13 | ribosomal protein S13 | -0.0215358 |
| BMERB1 | bMERB domain containing 1 | -0.021365 |
| RPS25 | ribosomal protein S25 | -0.0212801 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0212304 |
| INHBA | inhibin, beta A | -0.0211646 |
| S100A10 | S100 calcium binding protein A10 | -0.0211213 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0210346 |
| RPS3 | ribosomal protein S3 | -0.0209447 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0207896 |
| RPL36 | ribosomal protein L36 | -0.0198815 |
| NBEAL1 | neurobeachin-like 1 | -0.0197395 |
| PTGR1 | prostaglandin reductase 1 | -0.0190913 |
| ENO1 | enolase 1, (alpha) | -0.0188775 |
| RPS17 | ribosomal protein S17 | -0.0186543 |
| KPNB1 | karyopherin (importin) beta 1 | -0.01833 |
| RIGI | RNA sensor RIG-I | -0.0181603 |
| RPL35 | ribosomal protein L35 | -0.0177249 |
| TENM3 | teneurin transmembrane protein 3 | -0.0176019 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0175596 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0175228 |
