| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gefitinib_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPAG9 | sperm associated antigen 9 | 0.100667 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0939833 |
| PHIP | pleckstrin homology domain interacting protein | 0.0831163 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0830622 |
| NTM | neurotrimin | 0.0720135 |
| LDHA | lactate dehydrogenase A | 0.071625 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0690966 |
| FBXO11 | F-box protein 11 | 0.068474 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0628164 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0599209 |
| FAM171B | family with sequence similarity 171, member B | 0.0588333 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.058814 |
| PCDH9 | protocadherin 9 | 0.0559258 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0556554 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0556077 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0506671 |
| PRRC2C | proline-rich coiled-coil 2C | 0.050035 |
| WDR43 | WD repeat domain 43 | 0.0494337 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0486429 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0448972 |
| ENAH | enabled homolog (Drosophila) | 0.0437561 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.0420533 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0417656 |
| MTF2 | metal response element binding transcription factor 2 | 0.0414418 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0414385 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0413187 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0406127 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0403808 |
| BRD2 | bromodomain containing 2 | 0.0396312 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0385093 |
| THBS1 | thrombospondin 1 | 0.0373059 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0372015 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.036717 |
| USP34 | ubiquitin specific peptidase 34 | 0.0365574 |
| RAB30 | RAB30, member RAS oncogene family | 0.0360266 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0356404 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0353034 |
| ITSN2 | intersectin 2 | 0.0351715 |
| PLS3 | plastin 3 | 0.0346358 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.034405 |
| GAB2 | GRB2-associated binding protein 2 | 0.0339766 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0339005 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0330446 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.032799 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0327268 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.032163 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0320871 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | 0.0319269 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0316252 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0315095 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0314707 |
| ORC4 | origin recognition complex, subunit 4 | 0.031418 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.031237 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.030789 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0307552 |
| MEMO1 | mediator of cell motility 1 | 0.0307335 |
| MAP1B | microtubule-associated protein 1B | 0.0305224 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0304297 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0302201 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0301882 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0301042 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0296044 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0294545 |
| POU2F1 | POU class 2 homeobox 1 | 0.0294004 |
| RIGI | RNA sensor RIG-I | 0.0291615 |
| KLF10 | Kruppel-like factor 10 | 0.0290872 |
| FOXG1 | forkhead box G1 | 0.0290769 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0288978 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0288004 |
| ABI2 | abl-interactor 2 | 0.0286663 |
| TOX | thymocyte selection-associated high mobility group box | 0.0285871 |
| GANAB | glucosidase, alpha; neutral AB | 0.0285181 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0284974 |
| TPD52 | tumor protein D52 | 0.0282298 |
| CDH19 | cadherin 19, type 2 | 0.0282033 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0281701 |
| PDS5A | PDS5 cohesin associated factor A | 0.0281575 |
| LPIN2 | lipin 2 | 0.028151 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.02812 |
| EP300 | E1A binding protein p300 | 0.0279192 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.027707 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0274648 |
| EMP1 | epithelial membrane protein 1 | 0.0274274 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.027419 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.027403 |
| HELZ | helicase with zinc finger | 0.027387 |
| VMP1 | vacuole membrane protein 1 | 0.0273073 |
| ANXA1 | annexin A1 | 0.0271604 |
| ITGAV | integrin, alpha V | 0.0271214 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0270952 |
| PDS5B | PDS5 cohesin associated factor B | 0.0270441 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0269574 |
| FUS | FUS RNA binding protein | 0.0268832 |
| PTK2 | protein tyrosine kinase 2 | 0.0268813 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0266943 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0265353 |
| GLG1 | golgi glycoprotein 1 | 0.0263533 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0263359 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0263273 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0263269 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | -0.113228 |
| RPS2 | ribosomal protein S2 | -0.090794 |
| VIM | vimentin | -0.0856337 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0822232 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0803282 |
| RPS8 | ribosomal protein S8 | -0.0706334 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0699127 |
| POTEF | POTE ankyrin domain family, member F | -0.0695345 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0688129 |
| SNX6 | sorting nexin 6 | -0.068578 |
| H1-4 | H1.4 linker histone, cluster member | -0.0677981 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0667746 |
| MKI67 | marker of proliferation Ki-67 | -0.0609253 |
| TSC22D2 | TSC22 domain family, member 2 | -0.05734 |
| RAD51B | RAD51 paralog B | -0.0550871 |
| RPS16 | ribosomal protein S16 | -0.0549955 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0524028 |
| RHEB | Ras homolog enriched in brain | -0.0496743 |
| PTMA | prothymosin, alpha | -0.0486206 |
| TMSB4X | thymosin beta 4, X-linked | -0.0468688 |
| RPLP1 | ribosomal protein, large, P1 | -0.0443747 |
| PRTG | protogenin | -0.0431589 |
| OGA | O-GlcNAcase | -0.0421705 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0419116 |
| RPL6 | ribosomal protein L6 | -0.0418864 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0414744 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0405442 |
| HMGB2 | high mobility group box 2 | -0.0405042 |
| RPS12 | ribosomal protein S12 | -0.0399777 |
| TMSB10 | thymosin beta 10 | -0.0398599 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.039695 |
| CENPF | centromere protein F, 350/400kDa | -0.0389669 |
| RPL37 | ribosomal protein L37 | -0.038891 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0387373 |
| MAP4 | microtubule-associated protein 4 | -0.0386766 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0381999 |
| DSTN | destrin (actin depolymerizing factor) | -0.0380039 |
| CLTC | clathrin, heavy chain (Hc) | -0.0375216 |
| COL5A2 | collagen, type V, alpha 2 | -0.037221 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0370992 |
| DPYD | dihydropyrimidine dehydrogenase | -0.037067 |
| PROS1 | protein S (alpha) | -0.0363071 |
| PALLD | palladin, cytoskeletal associated protein | -0.0362698 |
| RPL38 | ribosomal protein L38 | -0.0354961 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0349928 |
| RBM25 | RNA binding motif protein 25 | -0.0345841 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0343553 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0340505 |
| STAG2 | stromal antigen 2 | -0.0339454 |
| GPC3 | glypican 3 | -0.033927 |
| RPL4 | ribosomal protein L4 | -0.033886 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0336423 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0330754 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.032885 |
| TPX2 | TPX2, microtubule-associated | -0.0327609 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0327177 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0324407 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0323686 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0323077 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0322479 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0317837 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0316403 |
| KIF4A | kinesin family member 4A | -0.0314202 |
| RPS25 | ribosomal protein S25 | -0.0312985 |
| RPS10 | ribosomal protein S10 | -0.03057 |
| PDCD5 | programmed cell death 5 | -0.03031 |
| RPLP2 | ribosomal protein, large, P2 | -0.030059 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0299616 |
| HDAC2 | histone deacetylase 2 | -0.0297017 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0292774 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0291662 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0290861 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0287163 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.028666 |
| CBX3 | chromobox homolog 3 | -0.0286037 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0285212 |
| H1-5 | H1.5 linker histone, cluster member | -0.0284605 |
| RPS21 | ribosomal protein S21 | -0.0284473 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0283053 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0282646 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0281889 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0281815 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0280423 |
| RPL9 | ribosomal protein L9 | -0.0280238 |
| GPATCH8 | G patch domain containing 8 | -0.0278881 |
| ANXA5 | annexin A5 | -0.0278832 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0277789 |
| RPL7 | ribosomal protein L7 | -0.0277131 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0276234 |
| RPL12 | ribosomal protein L12 | -0.0275968 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0275841 |
| HDAC9 | histone deacetylase 9 | -0.0274675 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.027367 |
| CCNY | cyclin Y | -0.0273625 |
| TFRC | transferrin receptor | -0.0270335 |
| RAI1 | retinoic acid induced 1 | -0.0263257 |
| TEX11 | testis expressed 11 | -0.0263141 |
| LDHB | lactate dehydrogenase B | -0.0262625 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0260409 |
| MEIS2 | Meis homeobox 2 | -0.0260389 |
