| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gefitinib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.140181 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.107514 |
| COL6A3 | collagen, type VI, alpha 3 | 0.100413 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0903514 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0747507 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0727937 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0726625 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0723391 |
| NDRG1 | N-myc downstream regulated 1 | 0.0707852 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0601111 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0556222 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0529479 |
| VEGFA | vascular endothelial growth factor A | 0.05193 |
| NRXN3 | neurexin 3 | 0.0465589 |
| CD44 | CD44 molecule (Indian blood group) | 0.0445686 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0422046 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0417313 |
| YME1L1 | YME1-like 1 ATPase | 0.0407663 |
| RND3 | Rho family GTPase 3 | 0.0404253 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.038594 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0384404 |
| CADM1 | cell adhesion molecule 1 | 0.0378673 |
| HIP1 | huntingtin interacting protein 1 | 0.0367517 |
| CD47 | CD47 molecule | 0.0366585 |
| FAM13A | family with sequence similarity 13, member A | 0.0363237 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0356298 |
| ANXA1 | annexin A1 | 0.0355942 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0354242 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0351376 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0350462 |
| SUCO | SUN domain containing ossification factor | 0.0344466 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0338978 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0337375 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0336486 |
| ATP13A3 | ATPase type 13A3 | 0.0335049 |
| ANXA2 | annexin A2 | 0.0334957 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0334822 |
| RNF145 | ring finger protein 145 | 0.0317033 |
| SDC4 | syndecan 4 | 0.031628 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.031433 |
| FOXJ3 | forkhead box J3 | 0.0312788 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0312083 |
| XPO1 | exportin 1 | 0.0307114 |
| ZNF292 | zinc finger protein 292 | 0.0300851 |
| ADM | adrenomedullin | 0.0298071 |
| WASF2 | WAS protein family, member 2 | 0.0295773 |
| GOLGA4 | golgin A4 | 0.029566 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0294648 |
| CALR | calreticulin | 0.0292057 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0290631 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.028892 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0286791 |
| OPTN | optineurin | 0.028569 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0285498 |
| KLHDC10 | kelch domain containing 10 | 0.028511 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0284423 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.028033 |
| RYBP | RING1 and YY1 binding protein | 0.027725 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0268745 |
| RLF | rearranged L-myc fusion | 0.0267695 |
| COG5 | component of oligomeric golgi complex 5 | 0.0267289 |
| CCNG2 | cyclin G2 | 0.0260336 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0258254 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0258029 |
| SEC24A | SEC24 family member A | 0.0255607 |
| CLINT1 | clathrin interactor 1 | 0.0254771 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0254418 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0252527 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.025155 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0245674 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0244704 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0243888 |
| SQSTM1 | sequestosome 1 | 0.0242931 |
| HSPB11 | heat shock protein family B (small), member 11 | 0.0239484 |
| LAMB1 | laminin, beta 1 | 0.0238703 |
| EMP1 | epithelial membrane protein 1 | 0.0238581 |
| ARRDC3 | arrestin domain containing 3 | 0.0237422 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0237331 |
| SRP54 | signal recognition particle 54kDa | 0.0236412 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0233258 |
| USP24 | ubiquitin specific peptidase 24 | 0.023278 |
| USP15 | ubiquitin specific peptidase 15 | 0.0232346 |
| L1CAM | L1 cell adhesion molecule | 0.0229777 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0229567 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0229489 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0229407 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0227898 |
| INSIG2 | insulin induced gene 2 | 0.0227753 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0226152 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0225496 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.022317 |
| COG6 | component of oligomeric golgi complex 6 | 0.0222909 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0222754 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0221054 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0219282 |
| SETD5 | SET domain containing 5 | 0.0216738 |
| F11R | F11 receptor | 0.0215352 |
| TAGLN2 | transgelin 2 | 0.021391 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0213816 |
| CCNL1 | cyclin L1 | 0.0213049 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.177043 |
| TMSB10 | thymosin beta 10 | -0.129849 |
| MT2A | metallothionein 2A | -0.124761 |
| VIM | vimentin | -0.0746846 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0730359 |
| COL1A1 | collagen, type I, alpha 1 | -0.0730325 |
| AHNAK | AHNAK nucleoprotein | -0.0706876 |
| UBC | ubiquitin C | -0.0653252 |
| ENO1 | enolase 1, (alpha) | -0.0645712 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0637498 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0585698 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0584492 |
| EGFR | epidermal growth factor receptor | -0.0557123 |
| CCNI | cyclin I | -0.0539973 |
| FN1 | fibronectin 1 | -0.0532202 |
| ACTG1 | actin gamma 1 | -0.0531419 |
| CALD1 | caldesmon 1 | -0.050118 |
| POTEF | POTE ankyrin domain family, member F | -0.0483158 |
| RPLP1 | ribosomal protein, large, P1 | -0.0453192 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0448441 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0444989 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0442707 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0441555 |
| HMGA2 | high mobility group AT-hook 2 | -0.0426681 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0421044 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0413674 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0412286 |
| GLIS3 | GLIS family zinc finger 3 | -0.0410431 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0403883 |
| RPL28 | ribosomal protein L28 | -0.0396119 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0394984 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0393657 |
| FAM20C | family with sequence similarity 20, member C | -0.039356 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0388413 |
| RPL37A | ribosomal protein L37a | -0.0384751 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0379295 |
| FLNA | filamin A, alpha | -0.0375143 |
| JMJD1C | jumonji domain containing 1C | -0.0372942 |
| WTAP | Wilms tumor 1 associated protein | -0.0372903 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0372744 |
| SMYD3 | SET and MYND domain containing 3 | -0.0361041 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0347027 |
| CDK6 | cyclin-dependent kinase 6 | -0.0344432 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0338802 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0333516 |
| RIGI | RNA sensor RIG-I | -0.0331491 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0330583 |
| SRPK2 | SRSF protein kinase 2 | -0.0327881 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.032236 |
| PTMA | prothymosin, alpha | -0.0321534 |
| RTN4 | reticulon 4 | -0.0320369 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0320278 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0319906 |
| FTL | ferritin, light polypeptide | -0.0319512 |
| MYO10 | myosin X | -0.0314836 |
| LONP2 | lon peptidase 2, peroxisomal | -0.0314636 |
| COL6A1 | collagen, type VI, alpha 1 | -0.031363 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0311588 |
| TNS3 | tensin 3 | -0.0308775 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0307425 |
| SEPTIN7 | septin 7 | -0.0305279 |
| CALU | calumenin | -0.0305036 |
| MT1X | metallothionein 1X | -0.0304597 |
| ZNF207 | zinc finger protein 207 | -0.0299514 |
| PRSS23 | protease, serine, 23 | -0.02919 |
| ANXA5 | annexin A5 | -0.0291607 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0290969 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0290568 |
| TOP1 | topoisomerase (DNA) I | -0.0289702 |
| QKI | QKI, KH domain containing, RNA binding | -0.0289586 |
| IL6 | interleukin 6 | -0.0287514 |
| STK17A | serine/threonine kinase 17a | -0.0286627 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0285931 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0285881 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0285703 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0285304 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0284922 |
| SNX14 | sorting nexin 14 | -0.0281188 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0277862 |
| CENPF | centromere protein F, 350/400kDa | -0.0277702 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0275894 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0275713 |
| THOC2 | THO complex 2 | -0.0274584 |
| MEF2A | myocyte enhancer factor 2A | -0.0273107 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0270711 |
| AFDN | afadin, adherens junction formation factor | -0.0269308 |
| TPM4 | tropomyosin 4 | -0.0268174 |
| PRELID2 | PRELI domain containing 2 | -0.0267814 |
| EXOC4 | exocyst complex component 4 | -0.0266808 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0266509 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0261627 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0259048 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0258198 |
| RPL15 | ribosomal protein L15 | -0.0256927 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0256222 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0254384 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0253764 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0253657 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.025239 |
| RPS19 | ribosomal protein S19 | -0.0250984 |
