| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gefitinib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.14605 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.145344 |
| LDHA | lactate dehydrogenase A | 0.116034 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.106981 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.101928 |
| ANXA2 | annexin A2 | 0.101719 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.101281 |
| SDC4 | syndecan 4 | 0.0883012 |
| JMJD1C | jumonji domain containing 1C | 0.06491 |
| VIM | vimentin | 0.0623443 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0611498 |
| ANXA1 | annexin A1 | 0.059135 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.054028 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.053856 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0526068 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0520871 |
| FLNB | filamin B, beta | 0.0457829 |
| PTMA | prothymosin, alpha | 0.0455556 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0451149 |
| NDRG1 | N-myc downstream regulated 1 | 0.0440382 |
| MAP1B | microtubule-associated protein 1B | 0.0429826 |
| IGF2 | insulin-like growth factor 2 | 0.0422781 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0409953 |
| IER3 | immediate early response 3 | 0.0408989 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0393963 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0379285 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0374908 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0368624 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0357934 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0357089 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0356239 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0350587 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0345433 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0341804 |
| PKM | pyruvate kinase, muscle | 0.034067 |
| INSIG1 | insulin induced gene 1 | 0.0330997 |
| LMO7 | LIM domain 7 | 0.0320785 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0311115 |
| ACTN1 | actinin, alpha 1 | 0.0307521 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.03056 |
| MT2A | metallothionein 2A | 0.0297453 |
| CCNL1 | cyclin L1 | 0.0294394 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0293241 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0292599 |
| CAPRIN2 | caprin family member 2 | 0.0291269 |
| SKIL | SKI-like proto-oncogene | 0.0290914 |
| JUN | jun proto-oncogene | 0.0289816 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.028644 |
| YME1L1 | YME1-like 1 ATPase | 0.0285956 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0284552 |
| B2M | beta-2-microglobulin | 0.0281513 |
| HMGA2 | high mobility group AT-hook 2 | 0.0280893 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0280693 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0280279 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0279773 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0279644 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0278896 |
| RNF217 | ring finger protein 217 | 0.02772 |
| ADM | adrenomedullin | 0.0275857 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0273738 |
| SLC38A2 | solute carrier family 38, member 2 | 0.027215 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0271634 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0263301 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0262969 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0262196 |
| RAI1 | retinoic acid induced 1 | 0.0261898 |
| KLF6 | Kruppel-like factor 6 | 0.0260716 |
| SEC24A | SEC24 family member A | 0.0259822 |
| ATP13A3 | ATPase type 13A3 | 0.0256884 |
| RAI14 | retinoic acid induced 14 | 0.0256359 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0252709 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0252011 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0251795 |
| DST | dystonin | 0.0249014 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0248878 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0247953 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0246066 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0243938 |
| MSN | moesin | 0.0243616 |
| PYGL | phosphorylase, glycogen, liver | 0.0236693 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0233431 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0233331 |
| CAVIN1 | caveolae associated protein 1 | 0.0232814 |
| GOLGA2 | golgin A2 | 0.023223 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0232181 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0230463 |
| UTRN | utrophin | 0.0230026 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0229314 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0227948 |
| ARF4 | ADP-ribosylation factor 4 | 0.0227248 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0226476 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0225799 |
| TXNIP | thioredoxin interacting protein | 0.0224128 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0224051 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0223048 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0221815 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0221675 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0219603 |
| MORF4L1 | mortality factor 4 like 1 | 0.0219316 |
| CWC15 | CWC15 spliceosome-associated protein | 0.0218745 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMYD3 | SET and MYND domain containing 3 | -0.0985539 |
| AHNAK | AHNAK nucleoprotein | -0.0607054 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0601329 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0540228 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0523054 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0509878 |
| ZNF292 | zinc finger protein 292 | -0.0487081 |
| GOLGA4 | golgin A4 | -0.0470747 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.047007 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0468927 |
| RPL23 | ribosomal protein L23 | -0.0457253 |
| DIAPH3 | diaphanous-related formin 3 | -0.0454469 |
| FNIP1 | folliculin interacting protein 1 | -0.0439375 |
| OSMR | oncostatin M receptor | -0.0438278 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0433919 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0429702 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0422231 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0408884 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.0407564 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0400458 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0397135 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0389167 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0384813 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.038195 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.0380801 |
| SNX14 | sorting nexin 14 | -0.0370767 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0369406 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0363073 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0353685 |
| DENND4A | DENN/MADD domain containing 4A | -0.0345541 |
| RORA | RAR-related orphan receptor A | -0.0343405 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0339745 |
| RRBP1 | ribosome binding protein 1 | -0.0338152 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0334109 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0332029 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0331979 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0324463 |
| CENPF | centromere protein F, 350/400kDa | -0.0321611 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0319724 |
| RPLP1 | ribosomal protein, large, P1 | -0.0316904 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0313375 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0311505 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0310729 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0307523 |
| PDCD6IP | programmed cell death 6 interacting protein | -0.030267 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0297117 |
| CENPP | centromere protein P | -0.0294958 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0292108 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0291562 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0289719 |
| CPNE1 | copine I | -0.0289172 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.028822 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0287237 |
| RBM39 | RNA binding motif protein 39 | -0.0286112 |
| PREPL | prolyl endopeptidase-like | -0.0285405 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0285239 |
| PHF20 | PHD finger protein 20 | -0.0281445 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.0278702 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0278697 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0278642 |
| USP22 | ubiquitin specific peptidase 22 | -0.0277792 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0276378 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0273927 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0270475 |
| TNPO1 | transportin 1 | -0.0269396 |
| IPO7 | importin 7 | -0.0267903 |
| CDK8 | cyclin-dependent kinase 8 | -0.0267074 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0263625 |
| DENND5A | DENN/MADD domain containing 5A | -0.0259109 |
| RPL37 | ribosomal protein L37 | -0.0258933 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0255756 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0255215 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0253827 |
| PRELID2 | PRELI domain containing 2 | -0.0249717 |
| GPHN | gephyrin | -0.0249066 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0247155 |
| WDR45B | WD repeat domain 45B | -0.0245978 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0245548 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.02454 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0244776 |
| ZNF91 | zinc finger protein 91 | -0.0243204 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.024231 |
| TUT4 | terminal uridylyl transferase 4 | -0.0242031 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0238015 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0235589 |
| RPL27A | ribosomal protein L27a | -0.0232701 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0232682 |
| METAP2 | methionyl aminopeptidase 2 | -0.0229496 |
| RBM25 | RNA binding motif protein 25 | -0.0228672 |
| CLTC | clathrin, heavy chain (Hc) | -0.0227526 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0226328 |
| SLC38A9 | solute carrier family 38, member 9 | -0.0225974 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0224548 |
| ZNF721 | zinc finger protein 721 | -0.0224473 |
| MYO9A | myosin IXA | -0.0223557 |
| SSH2 | slingshot protein phosphatase 2 | -0.0223218 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0223014 |
| RPLP2 | ribosomal protein, large, P2 | -0.0222574 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0222538 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0222265 |
