| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gefitinib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gefitinib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.159414 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0907488 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.073027 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0587409 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0554561 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0522259 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0438499 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0428144 |
| TMEM156 | transmembrane protein 156 | 0.0416257 |
| VCL | vinculin | 0.0385957 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0385818 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0381879 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0372637 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0370127 |
| MT2A | metallothionein 2A | 0.0365205 |
| PELO | pelota homolog (Drosophila) | 0.0334079 |
| OSMR | oncostatin M receptor | 0.033223 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0309987 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0299152 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0298119 |
| NTN4 | netrin 4 | 0.0293845 |
| KSR1 | kinase suppressor of ras 1 | 0.028669 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0284814 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0281373 |
| TOP1 | topoisomerase (DNA) I | 0.0281168 |
| SMAD3 | SMAD family member 3 | 0.0272164 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0270026 |
| NRP1 | neuropilin 1 | 0.0267058 |
| UBC | ubiquitin C | 0.0266883 |
| IL6ST | interleukin 6 signal transducer | 0.0266798 |
| VMP1 | vacuole membrane protein 1 | 0.0266125 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0264262 |
| CENPF | centromere protein F, 350/400kDa | 0.0264012 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0258325 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0247809 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0246374 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0243478 |
| RBM39 | RNA binding motif protein 39 | 0.0241664 |
| VIM | vimentin | 0.0236425 |
| CD44 | CD44 molecule (Indian blood group) | 0.0233278 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0232862 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.023283 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0230482 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0229048 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0227646 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0223314 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0223083 |
| RAB31 | RAB31, member RAS oncogene family | 0.0221886 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0221782 |
| CAB39 | calcium binding protein 39 | 0.0221569 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0220334 |
| MAP1B | microtubule-associated protein 1B | 0.0220237 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0218183 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0217983 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.021719 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0212691 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0205059 |
| SEPTIN9 | septin 9 | 0.0203202 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0203033 |
| MYO10 | myosin X | 0.0201093 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0199684 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0198897 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0198277 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0196579 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0196331 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.019599 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0195743 |
| EREG | epiregulin | 0.0195319 |
| MKI67 | marker of proliferation Ki-67 | 0.0193122 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0190049 |
| SVIL | supervillin | 0.0188516 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0186179 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0185888 |
| BRD2 | bromodomain containing 2 | 0.0184792 |
| ANLN | anillin, actin binding protein | 0.0178992 |
| CLTC | clathrin, heavy chain (Hc) | 0.01788 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0177926 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0176792 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0176588 |
| AFDN | afadin, adherens junction formation factor | 0.0176251 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0174682 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.017448 |
| CDCP1 | CUB domain containing protein 1 | 0.0171432 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0171148 |
| GOLGA4 | golgin A4 | 0.0171003 |
| B2M | beta-2-microglobulin | 0.0169487 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0167894 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0167348 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0167104 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0166319 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0165597 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0165289 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0165103 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0164763 |
| TGM2 | transglutaminase 2 | 0.0164629 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0163646 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0161378 |
| SNX9 | sorting nexin 9 | 0.0161222 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.0160724 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.015987 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.11027 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0562236 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0550446 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0499345 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0447513 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0422984 |
| EFNA5 | ephrin-A5 | -0.0339644 |
| PTMA | prothymosin, alpha | -0.0336158 |
| TMSB10 | thymosin beta 10 | -0.0327149 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0321303 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0315134 |
| NDRG1 | N-myc downstream regulated 1 | -0.0313365 |
| STC2 | stanniocalcin 2 | -0.0287441 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0278904 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0271086 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0233736 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0205601 |
| FAM13A | family with sequence similarity 13, member A | -0.0204619 |
| GLIS3 | GLIS family zinc finger 3 | -0.0202835 |
| INTS6 | integrator complex subunit 6 | -0.0198714 |
| CADM1 | cell adhesion molecule 1 | -0.0195983 |
| SQSTM1 | sequestosome 1 | -0.0193749 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0182333 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0172922 |
| S100A6 | S100 calcium binding protein A6 | -0.0170478 |
| DENND5B | DENN/MADD domain containing 5B | -0.0170009 |
| ASPH | aspartate beta-hydroxylase | -0.0167424 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.016545 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | -0.0155321 |
| AEBP2 | AE binding protein 2 | -0.015433 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0152027 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0150303 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0149292 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0147716 |
| FBN1 | fibrillin 1 | -0.0147079 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0144227 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0139458 |
| DENND1A | DENN/MADD domain containing 1A | -0.0138073 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0135505 |
| RPLP1 | ribosomal protein, large, P1 | -0.0134409 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0132144 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0130986 |
| CTBP2 | C-terminal binding protein 2 | -0.0130919 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0128518 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0127971 |
| SLC35F3 | solute carrier family 35, member F3 | -0.012461 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0124515 |
| LRRC23 | leucine rich repeat containing 23 | -0.0122156 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0121881 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0118156 |
| MTDH | metadherin | -0.011783 |
| GNAS | GNAS complex locus | -0.0114264 |
| RPS6 | ribosomal protein S6 | -0.0111808 |
| HMGA1 | high mobility group AT-hook 1 | -0.0110835 |
| EGFR | epidermal growth factor receptor | -0.0110732 |
| TENM4 | teneurin transmembrane protein 4 | -0.0109079 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0108037 |
| RANBP17 | RAN binding protein 17 | -0.0107896 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0106679 |
| RPS8 | ribosomal protein S8 | -0.0105637 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0105528 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0105409 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.010508 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0104757 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.0104599 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.010148 |
| RAI14 | retinoic acid induced 14 | -0.010095 |
| TGFB1 | transforming growth factor, beta 1 | -0.00993875 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.00993513 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00990128 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.00982376 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.00975904 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.00964278 |
| RSF1 | remodeling and spacing factor 1 | -0.00962023 |
| TPCN1 | two pore segment channel 1 | -0.00950257 |
| RACK1 | receptor for activated C kinase 1 | -0.00944849 |
| SEPTIN7 | septin 7 | -0.00938749 |
| RPL37A | ribosomal protein L37a | -0.00932727 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00919269 |
| OXR1 | oxidation resistance 1 | -0.00914767 |
| PRKCA | protein kinase C, alpha | -0.00903872 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00903603 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.00894635 |
| RPL36 | ribosomal protein L36 | -0.00891977 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.00891087 |
| HYOU1 | hypoxia up-regulated 1 | -0.00882552 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00873896 |
| VAC14 | Vac14 homolog (S. cerevisiae) | -0.00872404 |
| RPL35A | ribosomal protein L35a | -0.00857785 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.00855614 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.00854416 |
| ACTG1 | actin gamma 1 | -0.00841729 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.00840312 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.00835982 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.00833313 |
| S100A10 | S100 calcium binding protein A10 | -0.0083187 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.00828522 |
| LMNA | lamin A/C | -0.00821946 |
| PTK2 | protein tyrosine kinase 2 | -0.00816392 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00814481 |
