Gemcitabine Gene Set

Dataset DrugBank Drug Targets
Category physical interactions
Type drug
Description A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. (Chemical Entities of Biological Interest Ontology, CHEBI_175901)
External Link http://www.drugbank.ca/drugs/DB00441
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Genes

11 interacting proteins for the Gemcitabine drug from the curated DrugBank Drug Targets dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
CDA cytidine deaminase
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
DCK deoxycytidine kinase
RRM1 ribonucleotide reductase M1
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
TYMS thymidylate synthetase