| Dataset | HMDB Metabolites of Enzymes |
| Category | physical interactions |
| Type | metabolite |
| Description | A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. (Chemical Entities of Biological Interest Ontology, CHEBI_175901) |
| External Link | http://www.hmdb.ca/metabolites/HMDB14584 |
| Similar Terms | |
| Downloads & Tools |
7 interacting proteins for the Gemcitabine metabolite from the curated HMDB Metabolites of Enzymes dataset.
| Symbol | Name |
|---|---|
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| CDA | cytidine deaminase |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic |
| DCK | deoxycytidine kinase |
| RRM1 | ribonucleotide reductase M1 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| TYMS | thymidylate synthetase |
