| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.124009 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.116366 |
| CALR | calreticulin | 0.111293 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.103199 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0980661 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0945199 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0941884 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.091665 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0911949 |
| B2M | beta-2-microglobulin | 0.0893054 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0881285 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0872064 |
| DST | dystonin | 0.0801057 |
| CANX | calnexin | 0.0792151 |
| MAP1B | microtubule-associated protein 1B | 0.0785585 |
| PKM | pyruvate kinase, muscle | 0.0778152 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0752357 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0744989 |
| TPM3 | tropomyosin 3 | 0.0731977 |
| FSTL1 | follistatin-like 1 | 0.0697748 |
| FN1 | fibronectin 1 | 0.0629276 |
| SQSTM1 | sequestosome 1 | 0.0624411 |
| POTEF | POTE ankyrin domain family, member F | 0.061915 |
| PODXL | podocalyxin-like | 0.0617651 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0613153 |
| TPM4 | tropomyosin 4 | 0.0608094 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0604637 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0598539 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0589238 |
| CD44 | CD44 molecule (Indian blood group) | 0.0581986 |
| TLE4 | transducin-like enhancer of split 4 | 0.0581676 |
| DSPP | dentin sialophosphoprotein | 0.0575827 |
| GOLGA4 | golgin A4 | 0.0570537 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0545465 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.054128 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0515322 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0501928 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0496461 |
| EZR | ezrin | 0.0492783 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0492191 |
| LDHA | lactate dehydrogenase A | 0.0463944 |
| CSTB | cystatin B (stefin B) | 0.0450056 |
| ENO1 | enolase 1, (alpha) | 0.0421069 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0416214 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0413322 |
| MSN | moesin | 0.0404855 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0393293 |
| TAGLN2 | transgelin 2 | 0.0391547 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0387586 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0379336 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0377491 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.037137 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0370429 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0367234 |
| RND3 | Rho family GTPase 3 | 0.0364393 |
| GOLGB1 | golgin B1 | 0.0363041 |
| NAV2 | neuron navigator 2 | 0.0360037 |
| ERBIN | erbb2 interacting protein | 0.0359506 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.035333 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0352084 |
| MT2A | metallothionein 2A | 0.0352063 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0351104 |
| BCL2L1 | BCL2-like 1 | 0.0350362 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0348371 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0346668 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0344497 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0341871 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0338937 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0338525 |
| RPS6 | ribosomal protein S6 | 0.0335675 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0334321 |
| DIAPH3 | diaphanous-related formin 3 | 0.0332757 |
| MYOF | myoferlin | 0.0332693 |
| TMSB4X | thymosin beta 4, X-linked | 0.0332066 |
| SPAG9 | sperm associated antigen 9 | 0.0326054 |
| MB21D2 | Mab-21 domain containing 2 | 0.0322165 |
| KLF6 | Kruppel-like factor 6 | 0.0321216 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0320774 |
| HELZ | helicase with zinc finger | 0.0318952 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0317904 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.031753 |
| JMJD1C | jumonji domain containing 1C | 0.0316655 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0316441 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0316254 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.031093 |
| FAM107B | family with sequence similarity 107, member B | 0.0307987 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0305999 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0304622 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0303305 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0302805 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0301925 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0300873 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0298783 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0298437 |
| SFTPA2 | surfactant protein A2 | 0.0296619 |
| E2F7 | E2F transcription factor 7 | 0.0295553 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0294281 |
| SON | SON DNA binding protein | 0.0293849 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0291142 |
| RPS2 | ribosomal protein S2 | 0.0290368 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.194016 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.184978 |
| AHNAK | AHNAK nucleoprotein | -0.157565 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.152684 |
| TMSB10 | thymosin beta 10 | -0.142034 |
| PLAT | plasminogen activator, tissue | -0.106009 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.102739 |
| FBN1 | fibrillin 1 | -0.0999095 |
| COL3A1 | collagen, type III, alpha 1 | -0.0981971 |
| NAV1 | neuron navigator 1 | -0.0867861 |
| COL1A2 | collagen, type I, alpha 2 | -0.0728737 |
| COL5A1 | collagen, type V, alpha 1 | -0.0681266 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0612686 |
| AUTS2 | autism susceptibility candidate 2 | -0.0572853 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0561261 |
| VIM | vimentin | -0.0476427 |
| CD99 | CD99 molecule | -0.0424731 |
| THBS2 | thrombospondin 2 | -0.0419369 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0399332 |
| LOX | lysyl oxidase | -0.0397668 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0396742 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0388611 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0383741 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0372772 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0368555 |
| NDRG1 | N-myc downstream regulated 1 | -0.036466 |
| RPS27A | ribosomal protein S27a | -0.0364428 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0362801 |
| FRMD4A | FERM domain containing 4A | -0.0356994 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0346165 |
| INTS6 | integrator complex subunit 6 | -0.0330218 |
| STC1 | stanniocalcin 1 | -0.032986 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0322014 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0321804 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.032162 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0316494 |
| OGA | O-GlcNAcase | -0.0299803 |
| SP3 | Sp3 transcription factor | -0.0298271 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0291452 |
| HLA-C | major histocompatibility complex, class I, C | -0.0282084 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0281005 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0274317 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0273395 |
| SUCNR1 | succinate receptor 1 | -0.0271251 |
| RPS24 | ribosomal protein S24 | -0.0269703 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0262399 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0259694 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0257107 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0255009 |
| LOXL2 | lysyl oxidase-like 2 | -0.025327 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0249351 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.024409 |
| CUX1 | cut-like homeobox 1 | -0.0241072 |
| HLA-B | major histocompatibility complex, class I, B | -0.0239633 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0238485 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0236873 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0230885 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0227932 |
| MT1X | metallothionein 1X | -0.0223318 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0222088 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0221164 |
| FLNB | filamin B, beta | -0.0220283 |
| EHBP1 | EH domain binding protein 1 | -0.0214921 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0210188 |
| RPS15 | ribosomal protein S15 | -0.0207384 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0207124 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0205016 |
| TNS3 | tensin 3 | -0.020431 |
| HLA-E | major histocompatibility complex, class I, E | -0.02033 |
| EFNA5 | ephrin-A5 | -0.0202751 |
| GPC6 | glypican 6 | -0.0199957 |
| AEBP2 | AE binding protein 2 | -0.0192132 |
| MX2 | MX dynamin-like GTPase 2 | -0.0188653 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0188432 |
| ZNF217 | zinc finger protein 217 | -0.0186761 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0186296 |
| S100A10 | S100 calcium binding protein A10 | -0.0184057 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0183911 |
| WTAP | Wilms tumor 1 associated protein | -0.0181728 |
| GNAS | GNAS complex locus | -0.0180028 |
| MTSS1 | metastasis suppressor 1 | -0.017631 |
| COL7A1 | collagen, type VII, alpha 1 | -0.017605 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.016482 |
| TMEM263 | transmembrane protein 263 | -0.0164467 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0164342 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0163752 |
| VCL | vinculin | -0.0162982 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0162462 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0161288 |
| TMOD1 | tropomodulin 1 | -0.0160331 |
| RPL28 | ribosomal protein L28 | -0.016007 |
| C1D | C1D nuclear receptor corepressor | -0.0159398 |
| IPO9 | importin 9 | -0.0157759 |
| KIFAP3 | kinesin-associated protein 3 | -0.0155441 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0155146 |
| PNPLA7 | patatin-like phospholipase domain containing 7 | -0.0154332 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0152318 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0151715 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0151345 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0151282 |
