| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.110711 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.107877 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.104087 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0984231 |
| RPS12 | ribosomal protein S12 | 0.0932005 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0769976 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0739174 |
| VMP1 | vacuole membrane protein 1 | 0.0721279 |
| RPL37A | ribosomal protein L37a | 0.0648529 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0644198 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0614328 |
| JMJD1C | jumonji domain containing 1C | 0.0595807 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0562465 |
| INTS6 | integrator complex subunit 6 | 0.0560421 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0557398 |
| FTL | ferritin, light polypeptide | 0.0555755 |
| HDAC9 | histone deacetylase 9 | 0.0531629 |
| HMGA2 | high mobility group AT-hook 2 | 0.0514728 |
| CPOX | coproporphyrinogen oxidase | 0.0501388 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.049181 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0489527 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.04883 |
| EPHA5 | EPH receptor A5 | 0.0486623 |
| EXOC6B | exocyst complex component 6B | 0.0479658 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0475515 |
| NEGR1 | neuronal growth regulator 1 | 0.0471051 |
| SERTAD2 | SERTA domain containing 2 | 0.046878 |
| RPS2 | ribosomal protein S2 | 0.0464005 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0462749 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0461734 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0458386 |
| RPS3 | ribosomal protein S3 | 0.045752 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0453321 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0452055 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0441933 |
| DENND5A | DENN/MADD domain containing 5A | 0.0433043 |
| NRXN3 | neurexin 3 | 0.0428565 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0427855 |
| RPL31 | ribosomal protein L31 | 0.0426061 |
| PCBP2 | poly(rC) binding protein 2 | 0.0422005 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0412735 |
| RPL12 | ribosomal protein L12 | 0.0411702 |
| CLDND1 | claudin domain containing 1 | 0.0409775 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0406703 |
| RPL3 | ribosomal protein L3 | 0.0402142 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0389278 |
| RPL11 | ribosomal protein L11 | 0.0386514 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0381524 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0375745 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0374155 |
| SLC38A2 | solute carrier family 38, member 2 | 0.036873 |
| MED13L | mediator complex subunit 13-like | 0.036319 |
| HSPA8 | heat shock 70kDa protein 8 | 0.036004 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0359566 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0356665 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0353608 |
| TENM3 | teneurin transmembrane protein 3 | 0.0352044 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0350209 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0349115 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0344998 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0332549 |
| RPS8 | ribosomal protein S8 | 0.0331315 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0328452 |
| RPL9 | ribosomal protein L9 | 0.032657 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0325836 |
| ETNK1 | ethanolamine kinase 1 | 0.0324244 |
| AHR | aryl hydrocarbon receptor | 0.0323889 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0312618 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0311995 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0311585 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0307946 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0305854 |
| RAD51B | RAD51 paralog B | 0.0305326 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.029961 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.029958 |
| GPR15 | G protein-coupled receptor 15 | 0.0298971 |
| RPS17 | ribosomal protein S17 | 0.02979 |
| CLTC | clathrin, heavy chain (Hc) | 0.0297256 |
| ARRDC3 | arrestin domain containing 3 | 0.0294634 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0293958 |
| HOMER1 | homer scaffolding protein 1 | 0.0293235 |
| ELP4 | elongator acetyltransferase complex subunit 4 | 0.0292092 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0288504 |
| IPO7 | importin 7 | 0.0281159 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0280485 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0275176 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0274971 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0272305 |
| RCOR1 | REST corepressor 1 | 0.0270348 |
| DPYD | dihydropyrimidine dehydrogenase | 0.026855 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0268481 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0265228 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.0262658 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.026257 |
| PCDH9 | protocadherin 9 | 0.0262241 |
| RPL37 | ribosomal protein L37 | 0.0261338 |
| B2M | beta-2-microglobulin | 0.0261032 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0256877 |
| GOLGB1 | golgin B1 | 0.0255738 |
| ZNF638 | zinc finger protein 638 | 0.0255163 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.139271 |
| TMSB10 | thymosin beta 10 | -0.13588 |
| NLGN1 | neuroligin 1 | -0.133654 |
| PTMA | prothymosin, alpha | -0.115624 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.106344 |
| ACTG1 | actin gamma 1 | -0.0922998 |
| MKI67 | marker of proliferation Ki-67 | -0.0874301 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0826813 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0814977 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0784039 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0776556 |
| PCDH7 | protocadherin 7 | -0.0755664 |
| VIM | vimentin | -0.0698819 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0668118 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0644243 |
| CENPF | centromere protein F, 350/400kDa | -0.0643486 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0633005 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0612937 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0599956 |
| YBX3 | Y box binding protein 3 | -0.0598003 |
| AREG | amphiregulin | -0.0592373 |
| ZNF804A | zinc finger protein 804A | -0.0570232 |
| MGAT4C | MGAT4 family, member C | -0.0561569 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0545059 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0540577 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0509254 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0485186 |
| TMEM41B | transmembrane protein 41B | -0.0483894 |
| TMEM123 | transmembrane protein 123 | -0.0467192 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0464115 |
| PFN1 | profilin 1 | -0.0460526 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0454068 |
| CLDN1 | claudin 1 | -0.0453007 |
| MMP12 | matrix metallopeptidase 12 | -0.0444216 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0440109 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0430823 |
| AHNAK | AHNAK nucleoprotein | -0.0430543 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0429153 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0417534 |
| CCND1 | cyclin D1 | -0.0408519 |
| KIF18B | kinesin family member 18B | -0.040113 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0391771 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0352435 |
| H1-0 | H1.0 linker histone | -0.034856 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0339522 |
| PRR11 | proline rich 11 | -0.033689 |
| TUBB | tubulin, beta class I | -0.0334682 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0328398 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.0327069 |
| TPX2 | TPX2, microtubule-associated | -0.0326948 |
| BRI3BP | BRI3 binding protein | -0.0326186 |
| CENPE | centromere protein E, 312kDa | -0.0325774 |
| NHSL1 | NHS-like 1 | -0.0322326 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0322057 |
| EDARADD | EDAR-associated death domain | -0.0321287 |
| NAV3 | neuron navigator 3 | -0.0314969 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0314758 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0310315 |
| DEK | DEK proto-oncogene | -0.0309554 |
| HMGB1 | high mobility group box 1 | -0.0301355 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0295712 |
| XPO1 | exportin 1 | -0.0293334 |
| RPS21 | ribosomal protein S21 | -0.0282715 |
| ZFR | zinc finger RNA binding protein | -0.0282548 |
| TUBA1C | tubulin, alpha 1c | -0.028249 |
| EHBP1 | EH domain binding protein 1 | -0.0282282 |
| SGO2 | shugoshin 2 | -0.0282095 |
| TUBA1B | tubulin, alpha 1b | -0.027988 |
| NEBL | nebulette | -0.0276625 |
| WDR45B | WD repeat domain 45B | -0.0275501 |
| KLF6 | Kruppel-like factor 6 | -0.0273419 |
| MAP1B | microtubule-associated protein 1B | -0.0271663 |
| CAVIN1 | caveolae associated protein 1 | -0.0271329 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0266766 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0263641 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0263019 |
| RPL38 | ribosomal protein L38 | -0.0261282 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0257324 |
| WDR43 | WD repeat domain 43 | -0.0254937 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.025402 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0252503 |
| GNAS | GNAS complex locus | -0.0252056 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0248885 |
| DST | dystonin | -0.0248731 |
| SRP72 | signal recognition particle 72kDa | -0.0247002 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.024564 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0244556 |
| LMAN1 | lectin, mannose-binding, 1 | -0.024381 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0242398 |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G | -0.0242275 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0241553 |
| H3-3B | H3.3 histone B | -0.0240937 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0240932 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.024054 |
| CBX3 | chromobox homolog 3 | -0.0236982 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0236632 |
| HMGA1 | high mobility group AT-hook 1 | -0.0233613 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0231466 |
| FUS | FUS RNA binding protein | -0.023105 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0230633 |
