| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.17792 |
| LPIN1 | lipin 1 | 0.139808 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0943555 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0894855 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.067787 |
| VCL | vinculin | 0.067457 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0652771 |
| SEPTIN9 | septin 9 | 0.0580061 |
| MCL1 | myeloid cell leukemia 1 | 0.0550479 |
| TLE4 | transducin-like enhancer of split 4 | 0.0542102 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0490521 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0469687 |
| ATXN1 | ataxin 1 | 0.0453862 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0452173 |
| FAM107B | family with sequence similarity 107, member B | 0.0448277 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0427247 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0421292 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0420801 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0417708 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0417234 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0413597 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0411962 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0411364 |
| POTEF | POTE ankyrin domain family, member F | 0.0409938 |
| MYO1E | myosin IE | 0.0389408 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0387994 |
| SIK3 | SIK family kinase 3 | 0.0387925 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0373584 |
| DGKH | diacylglycerol kinase, eta | 0.0373536 |
| MED13 | mediator complex subunit 13 | 0.0369498 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0364031 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0363313 |
| GOLGB1 | golgin B1 | 0.0363065 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0360437 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0360288 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0359502 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0354554 |
| TUFT1 | tuftelin 1 | 0.0348117 |
| PCBP2 | poly(rC) binding protein 2 | 0.0346681 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0342465 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0341944 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0339818 |
| SMAD3 | SMAD family member 3 | 0.0337885 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0332869 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0330658 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0326025 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0318643 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0317447 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0311612 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0305576 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0300248 |
| CANX | calnexin | 0.0293834 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0293697 |
| GPC5 | glypican 5 | 0.0284485 |
| RBM6 | RNA binding motif protein 6 | 0.0281535 |
| ERBIN | erbb2 interacting protein | 0.0281255 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0281126 |
| USP34 | ubiquitin specific peptidase 34 | 0.027892 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0275839 |
| INTS6 | integrator complex subunit 6 | 0.0272904 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.0269785 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0269519 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0268806 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0267926 |
| THBS1 | thrombospondin 1 | 0.0265134 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0264552 |
| ZNF638 | zinc finger protein 638 | 0.0264305 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | 0.0263461 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0263056 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0260389 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0259768 |
| VMP1 | vacuole membrane protein 1 | 0.0259281 |
| ACTN1 | actinin, alpha 1 | 0.0258862 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0257608 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0257571 |
| TXNRD1 | thioredoxin reductase 1 | 0.0257431 |
| JUP | junction plakoglobin | 0.0256767 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0256756 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0256203 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0253887 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0250509 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0248103 |
| MRTFA | myocardin related transcription factor A | 0.0248011 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0247009 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0246342 |
| LIMA1 | LIM domain and actin binding 1 | 0.0244767 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0243721 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0243067 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0240082 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0238645 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0236192 |
| HOMER1 | homer scaffolding protein 1 | 0.0235027 |
| FAT1 | FAT atypical cadherin 1 | 0.0234698 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0233589 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0232573 |
| FMNL2 | formin-like 2 | 0.0232211 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.023203 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0231207 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0230732 |
| RUNX1 | runt-related transcription factor 1 | 0.022884 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.469151 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.255628 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.103932 |
| PTMA | prothymosin, alpha | -0.0888744 |
| COL1A1 | collagen, type I, alpha 1 | -0.074999 |
| MEIS2 | Meis homeobox 2 | -0.0732115 |
| FAM13A | family with sequence similarity 13, member A | -0.0704942 |
| NRG1 | neuregulin 1 | -0.0673138 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0620879 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0611301 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0589638 |
| RPL19 | ribosomal protein L19 | -0.0581624 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0571765 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0549506 |
| RPL34 | ribosomal protein L34 | -0.0549181 |
| LSAMP | limbic system-associated membrane protein | -0.053086 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.052238 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0516046 |
| RPL38 | ribosomal protein L38 | -0.0512428 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0506435 |
| VIM | vimentin | -0.0503603 |
| NREP | neuronal regeneration related protein | -0.049892 |
| RPLP1 | ribosomal protein, large, P1 | -0.0484511 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0478526 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0467283 |
| PCDH9 | protocadherin 9 | -0.0466902 |
| WDR45B | WD repeat domain 45B | -0.0461416 |
| CCDC47 | coiled-coil domain containing 47 | -0.0459505 |
| NDRG1 | N-myc downstream regulated 1 | -0.045839 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.043731 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0433179 |
| RPL35A | ribosomal protein L35a | -0.0420109 |
| FNBP1 | formin binding protein 1 | -0.0415813 |
| RPL31 | ribosomal protein L31 | -0.0410675 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0409503 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0394138 |
| RPL23 | ribosomal protein L23 | -0.0391254 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0376081 |
| COL3A1 | collagen, type III, alpha 1 | -0.0373823 |
| RPS19 | ribosomal protein S19 | -0.0363621 |
| RPS24 | ribosomal protein S24 | -0.0362709 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0360912 |
| SYT1 | synaptotagmin I | -0.0349394 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0338902 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0331318 |
| TRIB2 | tribbles pseudokinase 2 | -0.032295 |
| CENPF | centromere protein F, 350/400kDa | -0.0320507 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0320094 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0315797 |
| RBM39 | RNA binding motif protein 39 | -0.0306499 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0305386 |
| CADM2 | cell adhesion molecule 2 | -0.0296375 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0295045 |
| KLF6 | Kruppel-like factor 6 | -0.0292933 |
| RPL32 | ribosomal protein L32 | -0.0291967 |
| TMSB10 | thymosin beta 10 | -0.0290177 |
| DPH6 | diphthamine biosynthesis 6 | -0.0286826 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.028042 |
| S100A9 | S100 calcium binding protein A9 | -0.0276174 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.027429 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0273181 |
| H3-3B | H3.3 histone B | -0.0268121 |
| PCDH15 | protocadherin-related 15 | -0.0266525 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0264541 |
| RPL35 | ribosomal protein L35 | -0.0253991 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0251417 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0249342 |
| RGS5 | regulator of G-protein signaling 5 | -0.0247956 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0246777 |
| SMYD3 | SET and MYND domain containing 3 | -0.024266 |
| S100A6 | S100 calcium binding protein A6 | -0.0240962 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.024051 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0240442 |
| FAM162A | family with sequence similarity 162, member A | -0.0240435 |
| LRRC7 | leucine rich repeat containing 7 | -0.0239768 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0238817 |
| PRR11 | proline rich 11 | -0.0238645 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0237684 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0237243 |
| CDK19 | cyclin-dependent kinase 19 | -0.0236762 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0236698 |
| GNAS | GNAS complex locus | -0.0236667 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0233278 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0231287 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0229535 |
| RPLP0 | ribosomal protein, large, P0 | -0.0228968 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0228605 |
| RPL27 | ribosomal protein L27 | -0.0228587 |
| SEPTIN2 | septin 2 | -0.0225812 |
| AOPEP | aminopeptidase O (putative) | -0.0224496 |
| CCND1 | cyclin D1 | -0.0221651 |
| DTNA | dystrobrevin, alpha | -0.0220839 |
| PLAT | plasminogen activator, tissue | -0.0220385 |
| RPS21 | ribosomal protein S21 | -0.0217611 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0217355 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0216589 |
| FTL | ferritin, light polypeptide | -0.0213519 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0211188 |
| ZNF124 | zinc finger protein 124 | -0.020867 |
| DIAPH3 | diaphanous-related formin 3 | -0.0207854 |
