| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.394386 |
| EXT1 | exostosin glycosyltransferase 1 | 0.249228 |
| INTS6 | integrator complex subunit 6 | 0.157756 |
| SMAD3 | SMAD family member 3 | 0.156575 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.115882 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0998623 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0953971 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0848011 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0812504 |
| MYO1E | myosin IE | 0.07512 |
| ANXA2 | annexin A2 | 0.0738426 |
| LCN2 | lipocalin 2 | 0.0706927 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0693708 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0671202 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0659031 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.064507 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0634311 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0628055 |
| B2M | beta-2-microglobulin | 0.0621993 |
| EFNB2 | ephrin-B2 | 0.0615166 |
| KYNU | kynureninase | 0.0564222 |
| ASPH | aspartate beta-hydroxylase | 0.0557452 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0549736 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0547315 |
| DST | dystonin | 0.0530373 |
| PKM | pyruvate kinase, muscle | 0.0523579 |
| PLSCR2 | phospholipid scramblase 2 | 0.0516424 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0498624 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0488798 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0478436 |
| TJP1 | tight junction protein 1 | 0.0463477 |
| TXNRD1 | thioredoxin reductase 1 | 0.045839 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0452876 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0450737 |
| HKDC1 | hexokinase domain containing 1 | 0.0440986 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0416175 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0411142 |
| RNF213 | ring finger protein 213 | 0.0405046 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0403934 |
| MAP7 | microtubule-associated protein 7 | 0.0403842 |
| SIK3 | SIK family kinase 3 | 0.0403054 |
| MCU | mitochondrial calcium uniporter | 0.0399335 |
| DSPP | dentin sialophosphoprotein | 0.0386483 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0382551 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0380005 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0376462 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0376007 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0368402 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0367523 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0364079 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0361995 |
| FAT1 | FAT atypical cadherin 1 | 0.0361425 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0353651 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0340376 |
| MYO5B | myosin VB | 0.0336158 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0335846 |
| FNIP2 | folliculin interacting protein 2 | 0.0330903 |
| EREG | epiregulin | 0.0330396 |
| CANX | calnexin | 0.031969 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0319627 |
| SEPTIN9 | septin 9 | 0.0316703 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0312117 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0309532 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0302511 |
| YAP1 | Yes-associated protein 1 | 0.0301978 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0301342 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0293539 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0290039 |
| PDZD8 | PDZ domain containing 8 | 0.0289849 |
| LAMA4 | laminin, alpha 4 | 0.0284715 |
| IFNGR1 | interferon gamma receptor 1 | 0.0284097 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0283861 |
| MYOF | myoferlin | 0.0277723 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0270969 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0270449 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0268218 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0268123 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0267239 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0265347 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0263478 |
| CTBP2 | C-terminal binding protein 2 | 0.0263347 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0263237 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0262259 |
| NABP1 | nucleic acid binding protein 1 | 0.0260725 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0259473 |
| LAMB3 | laminin, beta 3 | 0.0255949 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0255942 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0254014 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0252633 |
| DIAPH1 | diaphanous-related formin 1 | 0.025213 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0250968 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0250695 |
| TOP1 | topoisomerase (DNA) I | 0.0249942 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0249506 |
| CD44 | CD44 molecule (Indian blood group) | 0.0248748 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0247313 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0246688 |
| EXOC4 | exocyst complex component 4 | 0.0246117 |
| LDHA | lactate dehydrogenase A | 0.0245389 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.024382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.149653 |
| NDRG1 | N-myc downstream regulated 1 | -0.105885 |
| PTMA | prothymosin, alpha | -0.0844042 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0840912 |
| TXNIP | thioredoxin interacting protein | -0.0754557 |
| LYZ | lysozyme | -0.0730761 |
| NPSR1 | neuropeptide S receptor 1 | -0.0608658 |
| EGR1 | early growth response 1 | -0.0564864 |
| H1-0 | H1.0 linker histone | -0.048836 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0471052 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0458116 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.045408 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0427484 |
| WDR45B | WD repeat domain 45B | -0.0411956 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0404284 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0401937 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0396598 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0392164 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0391064 |
| HLA-B | major histocompatibility complex, class I, B | -0.0379432 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.03719 |
| XAF1 | XIAP associated factor 1 | -0.0365866 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0351912 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0346114 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0344952 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0334781 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0333199 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0332567 |
| RPL35A | ribosomal protein L35a | -0.0330543 |
| CCNL1 | cyclin L1 | -0.0330517 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0321805 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0318868 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.031555 |
| RNF149 | ring finger protein 149 | -0.0313255 |
| RBM39 | RNA binding motif protein 39 | -0.0302776 |
| PMP22 | peripheral myelin protein 22 | -0.0301276 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0294333 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.028943 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0287129 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0285123 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0281983 |
| PLSCR1 | phospholipid scramblase 1 | -0.0280328 |
| SPATA13 | spermatogenesis associated 13 | -0.0279142 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0278595 |
| TNS4 | tensin 4 | -0.026138 |
| KLF6 | Kruppel-like factor 6 | -0.026101 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0256847 |
| TMEM62 | transmembrane protein 62 | -0.0255505 |
| EFHD2 | EF-hand domain family, member D2 | -0.0253491 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0248821 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0247611 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0247276 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0246983 |
| RPL34 | ribosomal protein L34 | -0.0243109 |
| CSTB | cystatin B (stefin B) | -0.0240381 |
| KLHL24 | kelch-like family member 24 | -0.0238383 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0232651 |
| PTEN | phosphatase and tensin homolog | -0.0231967 |
| IL20RA | interleukin 20 receptor, alpha | -0.0229757 |
| S100A6 | S100 calcium binding protein A6 | -0.0227403 |
| SSH2 | slingshot protein phosphatase 2 | -0.022669 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0226655 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0225891 |
| TAOK3 | TAO kinase 3 | -0.0221688 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0220044 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0219293 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0218997 |
| S100A9 | S100 calcium binding protein A9 | -0.02181 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0217746 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0215955 |
| APOL6 | apolipoprotein L, 6 | -0.0215338 |
| PRKCA | protein kinase C, alpha | -0.0212056 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0211779 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.021169 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0210219 |
| ANXA3 | annexin A3 | -0.0207439 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0204847 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0204772 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0203512 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0201842 |
| TMSB10 | thymosin beta 10 | -0.0201729 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0201357 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0200915 |
| ACTN4 | actinin, alpha 4 | -0.0200445 |
| ALPK1 | alpha-kinase 1 | -0.0200231 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0199643 |
| CTSD | cathepsin D | -0.0199229 |
| H3-3B | H3.3 histone B | -0.0197864 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0197716 |
| TPM4 | tropomyosin 4 | -0.0197588 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0197176 |
| SMAP2 | small ArfGAP2 | -0.0196851 |
| UBC | ubiquitin C | -0.0196173 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0193361 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0192289 |
| VEGFA | vascular endothelial growth factor A | -0.0192037 |
| ATF4 | activating transcription factor 4 | -0.0191649 |
| CEP95 | centrosomal protein 95kDa | -0.0191019 |
| NKTR | natural killer cell triggering receptor | -0.0190812 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0189688 |
