| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM1 | cell adhesion molecule 1 | 0.350933 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.264643 |
| CD44 | CD44 molecule (Indian blood group) | 0.121189 |
| EXT1 | exostosin glycosyltransferase 1 | 0.1175 |
| CALR | calreticulin | 0.104735 |
| FNDC3B | fibronectin type III domain containing 3B | 0.099812 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0972988 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.094207 |
| VEGFA | vascular endothelial growth factor A | 0.0773884 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0761876 |
| ENO1 | enolase 1, (alpha) | 0.0745561 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0724594 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0695466 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0674235 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0659205 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0633941 |
| FN1 | fibronectin 1 | 0.0620254 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0604133 |
| CANX | calnexin | 0.0599934 |
| IL6 | interleukin 6 | 0.0590253 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0581429 |
| GOLGB1 | golgin B1 | 0.0570522 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0565486 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0538617 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0516429 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0500028 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0496419 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0491801 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0490908 |
| ARRDC3 | arrestin domain containing 3 | 0.0489256 |
| IL6ST | interleukin 6 signal transducer | 0.0489241 |
| B2M | beta-2-microglobulin | 0.0488273 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0488 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0487281 |
| STC2 | stanniocalcin 2 | 0.0479704 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0471673 |
| TXNRD1 | thioredoxin reductase 1 | 0.0438487 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0436087 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0435034 |
| FAM107B | family with sequence similarity 107, member B | 0.0422134 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0417225 |
| VCAN | versican | 0.0416925 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0413646 |
| CALU | calumenin | 0.0413237 |
| FAT1 | FAT atypical cadherin 1 | 0.0410742 |
| LDHA | lactate dehydrogenase A | 0.0407465 |
| SMAD3 | SMAD family member 3 | 0.0404292 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0402829 |
| SP100 | SP100 nuclear antigen | 0.0383577 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0382474 |
| HYOU1 | hypoxia up-regulated 1 | 0.0368629 |
| SQSTM1 | sequestosome 1 | 0.036853 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0365614 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0358952 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.035812 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.034179 |
| APP | amyloid beta (A4) precursor protein | 0.032808 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0324667 |
| PGM3 | phosphoglucomutase 3 | 0.0322607 |
| CLTC | clathrin, heavy chain (Hc) | 0.0316698 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0315333 |
| GOLGA4 | golgin A4 | 0.0311808 |
| ECE1 | endothelin converting enzyme 1 | 0.0308192 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.030489 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0304288 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0298135 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0296178 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0293319 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0290015 |
| VMP1 | vacuole membrane protein 1 | 0.028592 |
| TMF1 | TATA element modulatory factor 1 | 0.0283416 |
| MLF1 | myeloid leukemia factor 1 | 0.0280449 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0279375 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0276558 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0276393 |
| TRAM1 | translocation associated membrane protein 1 | 0.0275618 |
| PLEC | plectin | 0.0275217 |
| CDH13 | cadherin 13 | 0.0273513 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0269205 |
| RND3 | Rho family GTPase 3 | 0.0269028 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0268141 |
| RPL3 | ribosomal protein L3 | 0.0266597 |
| RPL7 | ribosomal protein L7 | 0.0261116 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0260087 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0259628 |
| INHBA | inhibin, beta A | 0.0256897 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.025433 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0253632 |
| PCBP2 | poly(rC) binding protein 2 | 0.025339 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0253365 |
| TPM3 | tropomyosin 3 | 0.0250463 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0249589 |
| MYO10 | myosin X | 0.0247787 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0245775 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0245755 |
| COL3A1 | collagen, type III, alpha 1 | 0.0244702 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0243841 |
| SEPTIN9 | septin 9 | 0.0241324 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0238389 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0238241 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.211642 |
| NDRG1 | N-myc downstream regulated 1 | -0.204878 |
| TMSB10 | thymosin beta 10 | -0.139727 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.118083 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.113201 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0954127 |
| COL5A1 | collagen, type V, alpha 1 | -0.0826953 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0779561 |
| LOX | lysyl oxidase | -0.0715482 |
| PRELID2 | PRELI domain containing 2 | -0.0700711 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0622768 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0614851 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0598013 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0577946 |
| MT1X | metallothionein 1X | -0.0574733 |
| PTMA | prothymosin, alpha | -0.0572313 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.055484 |
| MT2A | metallothionein 2A | -0.0551138 |
| GLIS3 | GLIS family zinc finger 3 | -0.0521759 |
| RPL35A | ribosomal protein L35a | -0.045233 |
| HMGA2 | high mobility group AT-hook 2 | -0.0437882 |
| CALD1 | caldesmon 1 | -0.0433037 |
| VIM | vimentin | -0.0429129 |
| AHNAK | AHNAK nucleoprotein | -0.0424015 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0423852 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0409312 |
| FBN1 | fibrillin 1 | -0.0397996 |
| FTL | ferritin, light polypeptide | -0.0392767 |
| PDE10A | phosphodiesterase 10A | -0.0391056 |
| CAVIN1 | caveolae associated protein 1 | -0.0373748 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0372896 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.036773 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0353345 |
| PGK1 | phosphoglycerate kinase 1 | -0.0334288 |
| VCL | vinculin | -0.0322877 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0314591 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0311765 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.030657 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.030183 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0295745 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0282949 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0280478 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0278195 |
| ANXA2 | annexin A2 | -0.0277091 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0275511 |
| FAM162A | family with sequence similarity 162, member A | -0.0255056 |
| RPL36 | ribosomal protein L36 | -0.0244897 |
| S100A9 | S100 calcium binding protein A9 | -0.0242087 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0241873 |
| COL6A1 | collagen, type VI, alpha 1 | -0.024146 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0236707 |
| PFN1 | profilin 1 | -0.0235019 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0229684 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0228514 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0225816 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0225622 |
| ZNF292 | zinc finger protein 292 | -0.022466 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0222681 |
| USP3 | ubiquitin specific peptidase 3 | -0.0221072 |
| ACTG1 | actin gamma 1 | -0.0220292 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0219906 |
| RUNX1 | runt-related transcription factor 1 | -0.0218312 |
| RPS21 | ribosomal protein S21 | -0.0216085 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0213033 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0211566 |
| RPS19 | ribosomal protein S19 | -0.0211207 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0210515 |
| GNAS | GNAS complex locus | -0.0209379 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.020693 |
| LMNA | lamin A/C | -0.0203995 |
| TMEM263 | transmembrane protein 263 | -0.0203036 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.020041 |
| CENPF | centromere protein F, 350/400kDa | -0.0197082 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0188669 |
| NAV1 | neuron navigator 1 | -0.018768 |
| BNC2 | basonuclin 2 | -0.0187057 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0186812 |
| EHD2 | EH-domain containing 2 | -0.0185662 |
| DST | dystonin | -0.0184865 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0182223 |
| RRBP1 | ribosome binding protein 1 | -0.0182138 |
| NREP | neuronal regeneration related protein | -0.0178676 |
| RPLP1 | ribosomal protein, large, P1 | -0.0178458 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0177155 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0176934 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0175034 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0173291 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0172703 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0170466 |
| RPL19 | ribosomal protein L19 | -0.0170049 |
| TGFB1 | transforming growth factor, beta 1 | -0.0168741 |
| CNKSR3 | CNKSR family member 3 | -0.0167721 |
| ACTN4 | actinin, alpha 4 | -0.0164372 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0162803 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0160918 |
| CPQ | carboxypeptidase Q | -0.0160634 |
| TPM1 | tropomyosin 1 (alpha) | -0.0159307 |
| PRR16 | proline rich 16 | -0.0158468 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0158323 |
| PALLD | palladin, cytoskeletal associated protein | -0.0158084 |
