| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.222889 |
| RAI14 | retinoic acid induced 14 | 0.13751 |
| MTSS1 | metastasis suppressor 1 | 0.111378 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0824371 |
| MYOF | myoferlin | 0.0774402 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0774078 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0771675 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0755211 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0733382 |
| SMAD3 | SMAD family member 3 | 0.0633258 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0632069 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0601884 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0598653 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0597199 |
| FAM107B | family with sequence similarity 107, member B | 0.0544029 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0525696 |
| CD44 | CD44 molecule (Indian blood group) | 0.050363 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0494037 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0472925 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0471375 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0470645 |
| AOPEP | aminopeptidase O (putative) | 0.0465411 |
| SQSTM1 | sequestosome 1 | 0.0439199 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0434861 |
| RPL37A | ribosomal protein L37a | 0.0406973 |
| SIK3 | SIK family kinase 3 | 0.0405995 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0404354 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0402309 |
| SLK | STE20-like kinase | 0.0397692 |
| FTL | ferritin, light polypeptide | 0.0394275 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.039045 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0388646 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0386786 |
| RPL37 | ribosomal protein L37 | 0.0380894 |
| ECE1 | endothelin converting enzyme 1 | 0.0378911 |
| RPS12 | ribosomal protein S12 | 0.0371114 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0370152 |
| RPS6 | ribosomal protein S6 | 0.0367812 |
| RPS8 | ribosomal protein S8 | 0.0367503 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0366949 |
| MT2A | metallothionein 2A | 0.0363074 |
| CUL4B | cullin 4B | 0.0362004 |
| RPS3 | ribosomal protein S3 | 0.0351178 |
| KIAA1671 | KIAA1671 | 0.0350461 |
| TXNRD1 | thioredoxin reductase 1 | 0.0346746 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0346189 |
| GOLGB1 | golgin B1 | 0.0339159 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0336747 |
| SEPTIN9 | septin 9 | 0.0334592 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0332849 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0330943 |
| KIF16B | kinesin family member 16B | 0.033044 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0327754 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0325787 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0325573 |
| DOK5 | docking protein 5 | 0.0321415 |
| RPL26 | ribosomal protein L26 | 0.0321207 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0319308 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0315743 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0310504 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0308618 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0306884 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0305369 |
| ATP9A | ATPase, class II, type 9A | 0.0305095 |
| EFNA5 | ephrin-A5 | 0.0300554 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0294489 |
| JMJD1C | jumonji domain containing 1C | 0.0291334 |
| ANKRD11 | ankyrin repeat domain 11 | 0.029049 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0290209 |
| NRCAM | neuronal cell adhesion molecule | 0.0289524 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0289513 |
| TMSB4X | thymosin beta 4, X-linked | 0.02827 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0281786 |
| ENO1 | enolase 1, (alpha) | 0.0281627 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0280178 |
| CDCP1 | CUB domain containing protein 1 | 0.0280065 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0279362 |
| RPLP1 | ribosomal protein, large, P1 | 0.0276069 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0274677 |
| PGM3 | phosphoglucomutase 3 | 0.0272515 |
| ANO6 | anoctamin 6 | 0.0271126 |
| IL1B | interleukin 1, beta | 0.0270831 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0269314 |
| EGFR | epidermal growth factor receptor | 0.0268912 |
| RPL31 | ribosomal protein L31 | 0.0267538 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0266543 |
| MT1E | metallothionein 1E | 0.0265956 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0265147 |
| TXNIP | thioredoxin interacting protein | 0.0262374 |
| SYNJ2 | synaptojanin 2 | 0.0262278 |
| MEIS2 | Meis homeobox 2 | 0.0261085 |
| SFTPA2 | surfactant protein A2 | 0.0260563 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0260438 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.025952 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0259484 |
| RPS27 | ribosomal protein S27 | 0.0259039 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0258009 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0254164 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0251793 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0250666 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.279154 |
| FLNB | filamin B, beta | -0.220833 |
| NDRG1 | N-myc downstream regulated 1 | -0.190758 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.18597 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.155333 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.133926 |
| AHNAK | AHNAK nucleoprotein | -0.130985 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0984619 |
| ITGA6 | integrin, alpha 6 | -0.0933277 |
| EMP1 | epithelial membrane protein 1 | -0.0844149 |
| CLU | clusterin | -0.0816648 |
| TMSB10 | thymosin beta 10 | -0.0794636 |
| KRT17 | keratin 17, type I | -0.0778651 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0774794 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0712185 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0670272 |
| PGK1 | phosphoglycerate kinase 1 | -0.0635541 |
| PTMA | prothymosin, alpha | -0.0586355 |
| BCL2L1 | BCL2-like 1 | -0.0580058 |
| VCL | vinculin | -0.0576035 |
| FOXP1 | forkhead box P1 | -0.0575533 |
| PALLD | palladin, cytoskeletal associated protein | -0.057528 |
| ANXA2 | annexin A2 | -0.0553211 |
| NEK7 | NIMA-related kinase 7 | -0.0522124 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0519428 |
| LMNA | lamin A/C | -0.0515761 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0493801 |
| ANLN | anillin, actin binding protein | -0.0489416 |
| LAMA5 | laminin, alpha 5 | -0.0486787 |
| RBM39 | RNA binding motif protein 39 | -0.0484187 |
| SULF1 | sulfatase 1 | -0.0471583 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0459275 |
| RIGI | RNA sensor RIG-I | -0.0451775 |
| ACTN4 | actinin, alpha 4 | -0.0447326 |
| BLCAP | bladder cancer associated protein | -0.0441487 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.044143 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0438627 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0430186 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.042512 |
| PRELID2 | PRELI domain containing 2 | -0.0413318 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0412253 |
| UBC | ubiquitin C | -0.0404585 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0403173 |
| RPS21 | ribosomal protein S21 | -0.0400559 |
| OGA | O-GlcNAcase | -0.0397037 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0388432 |
| S100A10 | S100 calcium binding protein A10 | -0.0388004 |
| WASF2 | WAS protein family, member 2 | -0.0372385 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0369733 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0369167 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0367028 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0358306 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0352158 |
| RCOR1 | REST corepressor 1 | -0.0347834 |
| KRT6A | keratin 6A, type II | -0.0346741 |
| KRT14 | keratin 14, type I | -0.0346391 |
| GNAS | GNAS complex locus | -0.0342148 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0339202 |
| OXR1 | oxidation resistance 1 | -0.0335981 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0332883 |
| MT1X | metallothionein 1X | -0.0323385 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0322962 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0321157 |
| STC1 | stanniocalcin 1 | -0.0314541 |
| LDLR | low density lipoprotein receptor | -0.03081 |
| TPX2 | TPX2, microtubule-associated | -0.030749 |
| RIN2 | Ras and Rab interactor 2 | -0.0305684 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0302866 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0301933 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0298843 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.029773 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0296424 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0290733 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.028373 |
| S100A2 | S100 calcium binding protein A2 | -0.0279002 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0278288 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0277796 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0276888 |
| PFN1 | profilin 1 | -0.027399 |
| FRMD4B | FERM domain containing 4B | -0.0270278 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0269284 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0266928 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0265423 |
| MECOM | MDS1 and EVI1 complex locus | -0.0265402 |
| SYPL1 | synaptophysin-like 1 | -0.0264336 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0262412 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0261832 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0261632 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0258991 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0258588 |
| C4BPB | complement component 4 binding protein, beta | -0.0257199 |
| YBX3 | Y box binding protein 3 | -0.0255823 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0255569 |
| FN1 | fibronectin 1 | -0.0254689 |
| NECTIN1 | nectin cell adhesion molecule 1 | -0.0254643 |
| S100A4 | S100 calcium binding protein A4 | -0.0252269 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0251561 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0250855 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0249787 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0249698 |
