| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.198443 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.158311 |
| GDA | guanine deaminase | 0.108435 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.107764 |
| B2M | beta-2-microglobulin | 0.093928 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0906038 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0860871 |
| MYOF | myoferlin | 0.0846167 |
| LCN2 | lipocalin 2 | 0.0791507 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0785354 |
| TXNRD1 | thioredoxin reductase 1 | 0.0738133 |
| DSPP | dentin sialophosphoprotein | 0.070147 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0691347 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.068929 |
| CDK6 | cyclin-dependent kinase 6 | 0.0668069 |
| ANXA1 | annexin A1 | 0.0654716 |
| ITGA6 | integrin, alpha 6 | 0.06434 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0607015 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0590599 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0563184 |
| RPS12 | ribosomal protein S12 | 0.0543796 |
| KLHL29 | kelch-like family member 29 | 0.0535448 |
| HSPA8 | heat shock 70kDa protein 8 | 0.053237 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0517757 |
| SMAD3 | SMAD family member 3 | 0.0506093 |
| TJP1 | tight junction protein 1 | 0.0504956 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0503743 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0494961 |
| FTL | ferritin, light polypeptide | 0.0493958 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0481641 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0466012 |
| MB21D2 | Mab-21 domain containing 2 | 0.0464424 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0453562 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0450714 |
| DST | dystonin | 0.0413311 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0411835 |
| HYOU1 | hypoxia up-regulated 1 | 0.0402502 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.039909 |
| DSTN | destrin (actin depolymerizing factor) | 0.0395597 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0395526 |
| SLK | STE20-like kinase | 0.0374199 |
| RPS6 | ribosomal protein S6 | 0.0367744 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0365406 |
| SLTM | SAFB-like, transcription modulator | 0.0364628 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.035346 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0351784 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0351535 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0350918 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0347937 |
| EZR | ezrin | 0.0347535 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.034564 |
| RPL26 | ribosomal protein L26 | 0.0345585 |
| SQSTM1 | sequestosome 1 | 0.0344826 |
| SEPTIN9 | septin 9 | 0.0341263 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0337983 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0336645 |
| RPS17 | ribosomal protein S17 | 0.0332643 |
| MYO1E | myosin IE | 0.03325 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0323271 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0321732 |
| AHR | aryl hydrocarbon receptor | 0.0316606 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0309921 |
| INTS6 | integrator complex subunit 6 | 0.0305487 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0305096 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0303888 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0303625 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.029558 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0292364 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0290257 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0284947 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0278308 |
| RPS7 | ribosomal protein S7 | 0.0277595 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0275184 |
| EGFR | epidermal growth factor receptor | 0.0273942 |
| SP100 | SP100 nuclear antigen | 0.0265249 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0264434 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0263295 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0263252 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0263011 |
| TGFA | transforming growth factor, alpha | 0.0254937 |
| PRDX1 | peroxiredoxin 1 | 0.0254788 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0254 |
| RUNX1 | runt-related transcription factor 1 | 0.0251591 |
| HDAC9 | histone deacetylase 9 | 0.025043 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0249444 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0248463 |
| TPM3 | tropomyosin 3 | 0.0241752 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0241181 |
| LAMA4 | laminin, alpha 4 | 0.023978 |
| RPL11 | ribosomal protein L11 | 0.0238715 |
| ATXN1 | ataxin 1 | 0.0235303 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0233826 |
| MGAM2 | maltase-glucoamylase 2 (putative) | 0.0232744 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0229512 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0228732 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.02285 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0227927 |
| RPS25 | ribosomal protein S25 | 0.0227253 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0226012 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0224241 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.20439 |
| NPSR1 | neuropeptide S receptor 1 | -0.192308 |
| TMSB10 | thymosin beta 10 | -0.143373 |
| PTMA | prothymosin, alpha | -0.12319 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.122065 |
| NDRG1 | N-myc downstream regulated 1 | -0.108283 |
| PGK1 | phosphoglycerate kinase 1 | -0.105085 |
| AHNAK | AHNAK nucleoprotein | -0.0917544 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0869232 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0835623 |
| WDR45B | WD repeat domain 45B | -0.0803484 |
| H1-0 | H1.0 linker histone | -0.0778986 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0739701 |
| ANLN | anillin, actin binding protein | -0.0707484 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0706692 |
| RPS21 | ribosomal protein S21 | -0.0651072 |
| AGR2 | anterior gradient 2 | -0.0640383 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.063288 |
| S100A9 | S100 calcium binding protein A9 | -0.0621599 |
| KRT8 | keratin 8, type II | -0.0605814 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0585608 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0558697 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0556349 |
| S100A6 | S100 calcium binding protein A6 | -0.054758 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0545621 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0531836 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0524591 |
| RBM39 | RNA binding motif protein 39 | -0.0494703 |
| ITGB4 | integrin, beta 4 | -0.0489755 |
| S100A10 | S100 calcium binding protein A10 | -0.0489157 |
| UBC | ubiquitin C | -0.0461504 |
| ACTN4 | actinin, alpha 4 | -0.0460134 |
| RPL35A | ribosomal protein L35a | -0.0455363 |
| INSIG1 | insulin induced gene 1 | -0.0429012 |
| KRT7 | keratin 7, type II | -0.0416617 |
| ZNF292 | zinc finger protein 292 | -0.0409445 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0408978 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0405065 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0396174 |
| RPLP1 | ribosomal protein, large, P1 | -0.0389386 |
| TMEM123 | transmembrane protein 123 | -0.0380545 |
| GNAS | GNAS complex locus | -0.0375772 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0358984 |
| PRELID2 | PRELI domain containing 2 | -0.0358978 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0356559 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0354146 |
| AUTS2 | autism susceptibility candidate 2 | -0.035324 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0349158 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0347425 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0346344 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0345632 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0342701 |
| RPS27A | ribosomal protein S27a | -0.0339251 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0332815 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0332244 |
| H3-3B | H3.3 histone B | -0.0331367 |
| RPL23 | ribosomal protein L23 | -0.0330526 |
| RRBP1 | ribosome binding protein 1 | -0.0327292 |
| BCL2L1 | BCL2-like 1 | -0.0323718 |
| FAM13A | family with sequence similarity 13, member A | -0.0320363 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0318137 |
| RPS19 | ribosomal protein S19 | -0.0311867 |
| MKI67 | marker of proliferation Ki-67 | -0.0311448 |
| RPL34 | ribosomal protein L34 | -0.0311342 |
| PFN1 | profilin 1 | -0.0310404 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0309419 |
| ATF5 | activating transcription factor 5 | -0.0307215 |
| EPCAM | epithelial cell adhesion molecule | -0.0305497 |
| CLDN7 | claudin 7 | -0.0303836 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0302971 |
| PRSS3 | protease, serine, 3 | -0.0298384 |
| RPL38 | ribosomal protein L38 | -0.0292809 |
| RNF43 | ring finger protein 43 | -0.0292613 |
| KRT17 | keratin 17, type I | -0.0291093 |
| CCNY | cyclin Y | -0.0290139 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0289844 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0288807 |
| VEGFA | vascular endothelial growth factor A | -0.028734 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.027775 |
| LMNA | lamin A/C | -0.0274721 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0273471 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0273253 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0270517 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0268515 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0268319 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0267151 |
| ETV6 | ets variant 6 | -0.0265501 |
| KRT18 | keratin 18, type I | -0.0263523 |
| SETD5 | SET domain containing 5 | -0.0262401 |
| FASN | fatty acid synthase | -0.0261831 |
| DEK | DEK proto-oncogene | -0.0259824 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0259571 |
| TPD52 | tumor protein D52 | -0.0258448 |
| JUP | junction plakoglobin | -0.0256737 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0252259 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0251368 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0250234 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0249434 |
| PRKCA | protein kinase C, alpha | -0.0249282 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0249035 |
