| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.222603 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.207767 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.152014 |
| EXT1 | exostosin glycosyltransferase 1 | 0.141875 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.112788 |
| KRT18 | keratin 18, type I | 0.105412 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.101457 |
| ASPH | aspartate beta-hydroxylase | 0.0891446 |
| CALR | calreticulin | 0.0886464 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0868448 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0814692 |
| DSPP | dentin sialophosphoprotein | 0.0811458 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.067869 |
| KRT8 | keratin 8, type II | 0.0647817 |
| EREG | epiregulin | 0.0629036 |
| FAT1 | FAT atypical cadherin 1 | 0.0606724 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0595272 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0589102 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0584425 |
| LDHA | lactate dehydrogenase A | 0.0556604 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0553306 |
| CANX | calnexin | 0.0534603 |
| TXNRD1 | thioredoxin reductase 1 | 0.0531911 |
| MYO1E | myosin IE | 0.0524109 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.048885 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.048563 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.0480581 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0478111 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0470997 |
| TPM4 | tropomyosin 4 | 0.0464896 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0463524 |
| ABLIM1 | actin binding LIM protein 1 | 0.0462645 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0460095 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0458844 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0458161 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0448364 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0447101 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0441231 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0432313 |
| ABHD2 | abhydrolase domain containing 2 | 0.0428003 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0424978 |
| MYOF | myoferlin | 0.042311 |
| ACTG1 | actin gamma 1 | 0.041456 |
| SSR1 | signal sequence receptor, alpha | 0.0410184 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0402509 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0401907 |
| GDA | guanine deaminase | 0.039904 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0398384 |
| PDLIM5 | PDZ and LIM domain 5 | 0.038936 |
| CD164 | CD164 molecule, sialomucin | 0.0388647 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0387197 |
| HYOU1 | hypoxia up-regulated 1 | 0.0382771 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0382433 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0381727 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0379217 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0376021 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0374447 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0373406 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0371142 |
| EZR | ezrin | 0.0370938 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0369931 |
| TPM3 | tropomyosin 3 | 0.0365814 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0365768 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.036576 |
| TJP1 | tight junction protein 1 | 0.0360385 |
| PDZD8 | PDZ domain containing 8 | 0.0356243 |
| RPS12 | ribosomal protein S12 | 0.0352761 |
| TXNIP | thioredoxin interacting protein | 0.0351615 |
| EHF | ets homologous factor | 0.0351329 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0350339 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.034508 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0336089 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0334432 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0334371 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0334122 |
| UBC | ubiquitin C | 0.0329542 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0328786 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0328208 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0324951 |
| RAB10 | RAB10, member RAS oncogene family | 0.0323862 |
| POTEF | POTE ankyrin domain family, member F | 0.0323253 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0317892 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0314499 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0312485 |
| DSTN | destrin (actin depolymerizing factor) | 0.031146 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0310534 |
| MYO5B | myosin VB | 0.031017 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0308555 |
| PLS1 | plastin 1 | 0.0306745 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0305817 |
| KRT19 | keratin 19, type I | 0.0305735 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0305258 |
| RPLP0 | ribosomal protein, large, P0 | 0.0305252 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.030155 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0299689 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0298983 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0298478 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0296529 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0296411 |
| SERINC5 | serine incorporator 5 | 0.0290965 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.306691 |
| NPSR1 | neuropeptide S receptor 1 | -0.182415 |
| NDRG1 | N-myc downstream regulated 1 | -0.137081 |
| TMSB10 | thymosin beta 10 | -0.125794 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.109546 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0888314 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0870587 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0741519 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0684194 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0635769 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0626606 |
| TNS4 | tensin 4 | -0.0593712 |
| RPL35A | ribosomal protein L35a | -0.0572787 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0563693 |
| FAM13A | family with sequence similarity 13, member A | -0.055442 |
| ONECUT3 | one cut homeobox 3 | -0.0484544 |
| RPLP1 | ribosomal protein, large, P1 | -0.0480266 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0466585 |
| PRELID2 | PRELI domain containing 2 | -0.0445113 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0443627 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0442405 |
| PGK1 | phosphoglycerate kinase 1 | -0.0412076 |
| RPS19 | ribosomal protein S19 | -0.040231 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0392676 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0379279 |
| FLNB | filamin B, beta | -0.0374933 |
| RNF217 | ring finger protein 217 | -0.037266 |
| RPL36 | ribosomal protein L36 | -0.0365159 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0364408 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0357448 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0354818 |
| RNF43 | ring finger protein 43 | -0.0352663 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0345586 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0333739 |
| DENND1A | DENN/MADD domain containing 1A | -0.0330048 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0328642 |
| ITGB4 | integrin, beta 4 | -0.0328468 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0325351 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0325046 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0321828 |
| RPL34 | ribosomal protein L34 | -0.0317403 |
| CCNY | cyclin Y | -0.0316161 |
| CALB1 | calbindin 1, 28kDa | -0.0306808 |
| RAD51B | RAD51 paralog B | -0.0300363 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0297683 |
| RPL38 | ribosomal protein L38 | -0.0295465 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0291889 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0288791 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0280774 |
| GPHN | gephyrin | -0.0279207 |
| ZNF292 | zinc finger protein 292 | -0.0278768 |
| RRBP1 | ribosome binding protein 1 | -0.026794 |
| LSAMP | limbic system-associated membrane protein | -0.0265223 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0262582 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0261763 |
| WDR45B | WD repeat domain 45B | -0.0260783 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0254109 |
| NFIA | nuclear factor I/A | -0.025335 |
| RPS21 | ribosomal protein S21 | -0.0252518 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0248293 |
| RIN2 | Ras and Rab interactor 2 | -0.0245347 |
| FERMT1 | fermitin family member 1 | -0.0240556 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.023452 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0233814 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0233678 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -0.023199 |
| RNF149 | ring finger protein 149 | -0.0229013 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0226933 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0226141 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0225515 |
| RPL9 | ribosomal protein L9 | -0.0223819 |
| MT1X | metallothionein 1X | -0.0223035 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0221691 |
| RPL13A | ribosomal protein L13a | -0.0220649 |
| HMGB1 | high mobility group box 1 | -0.0219411 |
| GNAS | GNAS complex locus | -0.0219295 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0218727 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0213692 |
| FRMD5 | FERM domain containing 5 | -0.0212703 |
| RPS13 | ribosomal protein S13 | -0.0211038 |
| OGA | O-GlcNAcase | -0.0207837 |
| POU2F1 | POU class 2 homeobox 1 | -0.0205061 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.02048 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0204315 |
| NRN1 | neuritin 1 | -0.0204304 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0203007 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0200582 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0199667 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0198699 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.019863 |
| VCL | vinculin | -0.0197379 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0197007 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0195958 |
| NEMF | nuclear export mediator factor | -0.0194399 |
| MT2A | metallothionein 2A | -0.0193235 |
| AUTS2 | autism susceptibility candidate 2 | -0.0191987 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0188032 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0187737 |
| RPL23 | ribosomal protein L23 | -0.0186132 |
| MSI2 | musashi RNA-binding protein 2 | -0.0185996 |
