| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gemcitabine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.134587 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.128622 |
| SMAD3 | SMAD family member 3 | 0.126863 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.115562 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.103601 |
| PCBP2 | poly(rC) binding protein 2 | 0.102553 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0987094 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0919782 |
| ECE1 | endothelin converting enzyme 1 | 0.0817973 |
| RUNX2 | runt-related transcription factor 2 | 0.0786926 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0785068 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.075761 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0738352 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0722985 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0717092 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0689692 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0646807 |
| EREG | epiregulin | 0.0635108 |
| FAM107B | family with sequence similarity 107, member B | 0.0617857 |
| SEPTIN9 | septin 9 | 0.0604253 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0579461 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0569699 |
| ENO1 | enolase 1, (alpha) | 0.0568373 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0561285 |
| B2M | beta-2-microglobulin | 0.0535058 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.053494 |
| LDHA | lactate dehydrogenase A | 0.0534475 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0529617 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.052882 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.051735 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0512295 |
| ZNF638 | zinc finger protein 638 | 0.051007 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0503212 |
| MYO10 | myosin X | 0.0484872 |
| ATXN10 | ataxin 10 | 0.0481744 |
| PKM | pyruvate kinase, muscle | 0.0479983 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0474188 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0464046 |
| USP34 | ubiquitin specific peptidase 34 | 0.0457337 |
| WLS | wntless Wnt ligand secretion mediator | 0.0456994 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0454797 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0454194 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0453789 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0446881 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0442279 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0431118 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0431062 |
| SQSTM1 | sequestosome 1 | 0.043102 |
| VEGFA | vascular endothelial growth factor A | 0.0425888 |
| NAV2 | neuron navigator 2 | 0.0421429 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0420758 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0420287 |
| MB21D2 | Mab-21 domain containing 2 | 0.0419077 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0418448 |
| WNT7B | wingless-type MMTV integration site family, member 7B | 0.0416031 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.040354 |
| IFI44L | interferon-induced protein 44-like | 0.0402965 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0394147 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.038981 |
| LOXL2 | lysyl oxidase-like 2 | 0.0380923 |
| ZFP91 | ZFP91 zinc finger protein | 0.0372982 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0370971 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0370753 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0367452 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.036732 |
| CA12 | carbonic anhydrase XII | 0.0364936 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.036318 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0361407 |
| ATXN1 | ataxin 1 | 0.0353853 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0348816 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0348637 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0348616 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0345709 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0343416 |
| STC1 | stanniocalcin 1 | 0.0342861 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0341039 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0339022 |
| ANO6 | anoctamin 6 | 0.0334988 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0333169 |
| INTS6 | integrator complex subunit 6 | 0.0329102 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0325976 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.032595 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0325521 |
| ADM | adrenomedullin | 0.031865 |
| RORA | RAR-related orphan receptor A | 0.0318086 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0317501 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.031627 |
| EGFR | epidermal growth factor receptor | 0.0315672 |
| COPA | coatomer protein complex, subunit alpha | 0.031532 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0309995 |
| MEIS2 | Meis homeobox 2 | 0.0309897 |
| GPATCH2L | G patch domain containing 2-like | 0.0309496 |
| RAI14 | retinoic acid induced 14 | 0.030945 |
| SYNJ2 | synaptojanin 2 | 0.0301903 |
| SFTPA2 | surfactant protein A2 | 0.0300763 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0298313 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0297205 |
| TXNRD1 | thioredoxin reductase 1 | 0.0296872 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0290114 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0285714 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.188138 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.166964 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.138163 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.116042 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0902358 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.087387 |
| PTMA | prothymosin, alpha | -0.0814432 |
| RBM39 | RNA binding motif protein 39 | -0.0794861 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0784848 |
| FN1 | fibronectin 1 | -0.0781374 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0759798 |
| LOX | lysyl oxidase | -0.0734677 |
| GLCCI1 | glucocorticoid induced 1 | -0.0733525 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0726315 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0702111 |
| OSMR | oncostatin M receptor | -0.0694346 |
| HMGA2 | high mobility group AT-hook 2 | -0.0688394 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0662938 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0620665 |
| GPC6 | glypican 6 | -0.0598684 |
| FAM20C | family with sequence similarity 20, member C | -0.0560551 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0552689 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0542476 |
| RPLP1 | ribosomal protein, large, P1 | -0.0536476 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0533499 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0511937 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0511167 |
| ZNF804A | zinc finger protein 804A | -0.0505724 |
| OXR1 | oxidation resistance 1 | -0.050151 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0469786 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0468545 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0462319 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0451986 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0450427 |
| RPS21 | ribosomal protein S21 | -0.0431326 |
| RPL35A | ribosomal protein L35a | -0.0423408 |
| GNAS | GNAS complex locus | -0.0423279 |
| RPS19 | ribosomal protein S19 | -0.0414099 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0412588 |
| PRELID2 | PRELI domain containing 2 | -0.0405142 |
| VCL | vinculin | -0.0401602 |
| CDH13 | cadherin 13 | -0.0393997 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.038682 |
| GLIS3 | GLIS family zinc finger 3 | -0.038658 |
| NDRG1 | N-myc downstream regulated 1 | -0.0381482 |
| PRRX1 | paired related homeobox 1 | -0.0369521 |
| OGA | O-GlcNAcase | -0.036849 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0367741 |
| TNNC1 | troponin C type 1 (slow) | -0.0363212 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0358551 |
| MTSS1 | metastasis suppressor 1 | -0.0357257 |
| FTL | ferritin, light polypeptide | -0.035404 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.035316 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0348131 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0345477 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0340804 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0335332 |
| AHNAK | AHNAK nucleoprotein | -0.0334807 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0330727 |
| RPL36 | ribosomal protein L36 | -0.0327279 |
| RAI1 | retinoic acid induced 1 | -0.0319367 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0315439 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0310526 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0310148 |
| RPL34 | ribosomal protein L34 | -0.0303878 |
| KLF6 | Kruppel-like factor 6 | -0.0303627 |
| CDK17 | cyclin-dependent kinase 17 | -0.0300015 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0298813 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0291447 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0289701 |
| ANXA2 | annexin A2 | -0.02894 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0288494 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0286372 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0286201 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0284604 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0284567 |
| HAS2 | hyaluronan synthase 2 | -0.0280905 |
| TMSB4X | thymosin beta 4, X-linked | -0.0279755 |
| RNF24 | ring finger protein 24 | -0.0278031 |
| JMJD1C | jumonji domain containing 1C | -0.0270109 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0266208 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0265319 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0262974 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.025706 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0256721 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.025651 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0256468 |
| CD44 | CD44 molecule (Indian blood group) | -0.0255811 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0254735 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0254455 |
| RPL38 | ribosomal protein L38 | -0.0253394 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0251571 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0250969 |
| OFD1 | oral-facial-digital syndrome 1 | -0.0250261 |
| VIM | vimentin | -0.02491 |
| NUMB | numb homolog (Drosophila) | -0.0248886 |
| FDPS | farnesyl diphosphate synthase | -0.0247019 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0245518 |
| MT2A | metallothionein 2A | -0.0245111 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.024268 |
