| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.17654 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.128362 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.103241 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.102136 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0921876 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0900149 |
| TXNRD1 | thioredoxin reductase 1 | 0.0867462 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0810426 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0706634 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0694968 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0647725 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0591113 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0537748 |
| MYOF | myoferlin | 0.0528593 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0512405 |
| STC2 | stanniocalcin 2 | 0.0489454 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0488018 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.048716 |
| RPS12 | ribosomal protein S12 | 0.0465312 |
| CYTH1 | cytohesin 1 | 0.0461829 |
| HLA-A | major histocompatibility complex, class I, A | 0.0447334 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0430924 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0430517 |
| NRG1 | neuregulin 1 | 0.0430122 |
| GOLGA4 | golgin A4 | 0.0419592 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0409579 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0406848 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0405622 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0403901 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0402428 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0391392 |
| CCNL1 | cyclin L1 | 0.0387984 |
| KYNU | kynureninase | 0.0363952 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0359291 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0357847 |
| GDA | guanine deaminase | 0.0356066 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0353729 |
| B2M | beta-2-microglobulin | 0.0347828 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.034774 |
| RPS6 | ribosomal protein S6 | 0.034069 |
| RPS27 | ribosomal protein S27 | 0.0335397 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0334268 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0334198 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0332714 |
| CD109 | CD109 molecule | 0.0331848 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0329145 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0327594 |
| NCKAP1 | NCK-associated protein 1 | 0.0323855 |
| RPS25 | ribosomal protein S25 | 0.0316604 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0314442 |
| EGFR | epidermal growth factor receptor | 0.031357 |
| LDHA | lactate dehydrogenase A | 0.0312848 |
| USP37 | ubiquitin specific peptidase 37 | 0.0311457 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.031028 |
| EPGN | epithelial mitogen | 0.0306955 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0302393 |
| NUP58 | nucleoporin 58 | 0.0300366 |
| SIK3 | SIK family kinase 3 | 0.0293536 |
| COPA | coatomer protein complex, subunit alpha | 0.0288959 |
| CALR | calreticulin | 0.0288177 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0287775 |
| RPS17 | ribosomal protein S17 | 0.0286228 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0285546 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0285048 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0282572 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.028159 |
| HLA-B | major histocompatibility complex, class I, B | 0.0281213 |
| VRK2 | vaccinia related kinase 2 | 0.027892 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0278587 |
| KIF1B | kinesin family member 1B | 0.0277525 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0272417 |
| FAM107B | family with sequence similarity 107, member B | 0.0269359 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0268981 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0267844 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0265055 |
| MED13 | mediator complex subunit 13 | 0.02628 |
| KIF5B | kinesin family member 5B | 0.0256892 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0254134 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0253259 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0250217 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0249441 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0248766 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0248745 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0248712 |
| CUL3 | cullin 3 | 0.0247645 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.0244964 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0244398 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0244164 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0243743 |
| RAB18 | RAB18, member RAS oncogene family | 0.0243194 |
| ATXN1 | ataxin 1 | 0.0241083 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0240581 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0240454 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0239983 |
| SFTPA2 | surfactant protein A2 | 0.0238201 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0237561 |
| PTGES2 | prostaglandin E synthase 2 | 0.0237395 |
| MCL1 | myeloid cell leukemia 1 | 0.0236577 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0233129 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0233129 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.189683 |
| PM20D1 | peptidase M20 domain containing 1 | -0.187535 |
| GRAMD1B | GRAM domain containing 1B | -0.187295 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.16706 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.121798 |
| PTMA | prothymosin, alpha | -0.120426 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.100189 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.090371 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0826287 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0822585 |
| RPS27A | ribosomal protein S27a | -0.0724139 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.06872 |
| VIM | vimentin | -0.0670879 |
| CAVIN1 | caveolae associated protein 1 | -0.0644616 |
| BICC1 | BicC family RNA binding protein 1 | -0.0569299 |
| ASPH | aspartate beta-hydroxylase | -0.0557443 |
| FGB | fibrinogen beta chain | -0.0547101 |
| ACTG1 | actin gamma 1 | -0.0538785 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0523817 |
| AHNAK | AHNAK nucleoprotein | -0.0516033 |
| RPL23 | ribosomal protein L23 | -0.0511543 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0487072 |
| UBC | ubiquitin C | -0.0484966 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0464746 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0462293 |
| CMIP | c-Maf inducing protein | -0.046067 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0455581 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0435101 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0408782 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0402646 |
| RPL19 | ribosomal protein L19 | -0.0399087 |
| RPS21 | ribosomal protein S21 | -0.039631 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0389727 |
| FLNB | filamin B, beta | -0.0380398 |
| GNAS | GNAS complex locus | -0.0377814 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0369575 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0367608 |
| RAD51B | RAD51 paralog B | -0.0366103 |
| PDE8A | phosphodiesterase 8A | -0.036452 |
| LMNA | lamin A/C | -0.036041 |
| THBS1 | thrombospondin 1 | -0.035706 |
| MT2A | metallothionein 2A | -0.0351271 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0348196 |
| NEBL | nebulette | -0.0342351 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0339825 |
| KLF6 | Kruppel-like factor 6 | -0.031699 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0315056 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.03146 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.031432 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0312826 |
| PYGL | phosphorylase, glycogen, liver | -0.0312127 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0311576 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0308312 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0302768 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0294886 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0288258 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0287032 |
| IGF2 | insulin-like growth factor 2 | -0.0285814 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0280618 |
| DST | dystonin | -0.0270428 |
| WWOX | WW domain containing oxidoreductase | -0.027008 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0269726 |
| ACTN1 | actinin, alpha 1 | -0.0268266 |
| HMGB1 | high mobility group box 1 | -0.0265351 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0263936 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.025934 |
| ANXA2 | annexin A2 | -0.0258542 |
| ANLN | anillin, actin binding protein | -0.0257821 |
| RAI1 | retinoic acid induced 1 | -0.025746 |
| ZFHX3 | zinc finger homeobox 3 | -0.0256681 |
| RTN4 | reticulon 4 | -0.0252454 |
| CFDP1 | craniofacial development protein 1 | -0.0249475 |
| RPL36 | ribosomal protein L36 | -0.024557 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0244539 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.024272 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0242253 |
| BMP5 | bone morphogenetic protein 5 | -0.0241447 |
| TPM1 | tropomyosin 1 (alpha) | -0.0240886 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0240862 |
| PRR16 | proline rich 16 | -0.0229068 |
| MKI67 | marker of proliferation Ki-67 | -0.022726 |
| TPD52 | tumor protein D52 | -0.0224285 |
| MT1X | metallothionein 1X | -0.0222266 |
| RPL36AL | ribosomal protein L36a-like | -0.0220681 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0218529 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0217302 |
| FLNA | filamin A, alpha | -0.0215978 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0213853 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.021334 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0213003 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0212244 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0211382 |
| NNMT | nicotinamide N-methyltransferase | -0.0211185 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0210534 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0209576 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0209368 |
| CENPF | centromere protein F, 350/400kDa | -0.0208061 |
| SRGN | serglycin | -0.0207487 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.020744 |
| RPL38 | ribosomal protein L38 | -0.0205971 |
