| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.16884 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.12311 |
| TXNRD1 | thioredoxin reductase 1 | 0.106305 |
| MCL1 | myeloid cell leukemia 1 | 0.104945 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0982144 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0855555 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0835657 |
| ENO1 | enolase 1, (alpha) | 0.0797913 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0789637 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0789604 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0788834 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0785579 |
| COPA | coatomer protein complex, subunit alpha | 0.0776275 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0738662 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0717295 |
| CLTC | clathrin, heavy chain (Hc) | 0.0678281 |
| INTS6 | integrator complex subunit 6 | 0.0648198 |
| ANO6 | anoctamin 6 | 0.064593 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0637573 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0637184 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0627698 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0619524 |
| TPM3 | tropomyosin 3 | 0.0617307 |
| GOLGB1 | golgin B1 | 0.0609185 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0607277 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.059066 |
| CANX | calnexin | 0.0581812 |
| SPAG9 | sperm associated antigen 9 | 0.0579743 |
| HOMER1 | homer scaffolding protein 1 | 0.057856 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0575447 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0573262 |
| CRY1 | cryptochrome circadian clock 1 | 0.056682 |
| JMJD1C | jumonji domain containing 1C | 0.0560013 |
| ADAR | adenosine deaminase, RNA-specific | 0.0555183 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0553641 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0540961 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0538671 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0537742 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0526223 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0524013 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0514909 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0513559 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0505123 |
| RPS12 | ribosomal protein S12 | 0.0504214 |
| IPO7 | importin 7 | 0.0502016 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0494967 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0489722 |
| VMP1 | vacuole membrane protein 1 | 0.0489237 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0485199 |
| ATF6 | activating transcription factor 6 | 0.0480681 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0471714 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0463503 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0462493 |
| USP34 | ubiquitin specific peptidase 34 | 0.0460889 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0454274 |
| AFF4 | AF4/FMR2 family, member 4 | 0.045182 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0443836 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0443555 |
| RPL37 | ribosomal protein L37 | 0.0441699 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0436043 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.043059 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0429627 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0428544 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0419945 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0411257 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0404296 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0404071 |
| USP15 | ubiquitin specific peptidase 15 | 0.0399027 |
| CPNE1 | copine I | 0.0398744 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0396817 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0396236 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0391432 |
| MORF4L2 | mortality factor 4 like 2 | 0.0386147 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0385391 |
| PREPL | prolyl endopeptidase-like | 0.0383656 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0383412 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0382606 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.038123 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0380144 |
| RPS3 | ribosomal protein S3 | 0.0378976 |
| UBC | ubiquitin C | 0.0376816 |
| XPOT | exportin, tRNA | 0.0376081 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0368573 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0364792 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0361781 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0361205 |
| RAB10 | RAB10, member RAS oncogene family | 0.0357486 |
| PMM2 | phosphomannomutase 2 | 0.0357282 |
| EXOC6B | exocyst complex component 6B | 0.0351503 |
| RPL4 | ribosomal protein L4 | 0.0349548 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.03468 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0346217 |
| SCFD1 | sec1 family domain containing 1 | 0.0345001 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0341972 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0341042 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0340735 |
| TLN1 | talin 1 | 0.0339303 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0339048 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0336311 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0331877 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.170506 |
| YBX3 | Y box binding protein 3 | -0.0997576 |
| PTMA | prothymosin, alpha | -0.0982621 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0919259 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0916378 |
| EGR1 | early growth response 1 | -0.0777067 |
| PFN1 | profilin 1 | -0.0677681 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0617501 |
| RAD51B | RAD51 paralog B | -0.0603463 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.05921 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0546981 |
| GRAMD1B | GRAM domain containing 1B | -0.0545077 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0475795 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.047203 |
| PDE10A | phosphodiesterase 10A | -0.0472001 |
| MT2A | metallothionein 2A | -0.0449786 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0426407 |
| HMGA2 | high mobility group AT-hook 2 | -0.039296 |
| RPLP1 | ribosomal protein, large, P1 | -0.0385509 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0373424 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0366849 |
| IGF2 | insulin-like growth factor 2 | -0.0361221 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0345125 |
| SMIM44 | small integral membrane protein 44 | -0.0341818 |
| RPL38 | ribosomal protein L38 | -0.0325202 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0316328 |
| CBX3 | chromobox homolog 3 | -0.0311907 |
| CAVIN1 | caveolae associated protein 1 | -0.031015 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0304373 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0303663 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0294018 |
| RYR3 | ryanodine receptor 3 | -0.0290651 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0290261 |
| CENPF | centromere protein F, 350/400kDa | -0.0287479 |
| LDHB | lactate dehydrogenase B | -0.0280453 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0275718 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0275045 |
| RPL34 | ribosomal protein L34 | -0.0269701 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0268941 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0262099 |
| HMGA1 | high mobility group AT-hook 1 | -0.0260395 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0260011 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0257832 |
| BSG | basigin (Ok blood group) | -0.0257645 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0256313 |
| RPS15 | ribosomal protein S15 | -0.025427 |
| RPL35A | ribosomal protein L35a | -0.0252225 |
| DEK | DEK proto-oncogene | -0.0250737 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0248779 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0241416 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0241211 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.02406 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0239467 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.023882 |
| PHF14 | PHD finger protein 14 | -0.0238277 |
| S100A11 | S100 calcium binding protein A11 | -0.0237153 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0236106 |
| SEPTIN7 | septin 7 | -0.0234978 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0234798 |
| LATS2 | large tumor suppressor kinase 2 | -0.0231948 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0230866 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0230569 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0228309 |
| RPL19 | ribosomal protein L19 | -0.022713 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.022664 |
| MT1X | metallothionein 1X | -0.022642 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0226012 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0225724 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0225403 |
| RBM25 | RNA binding motif protein 25 | -0.0222655 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0220903 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0213035 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.0210714 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.020973 |
| RPS19 | ribosomal protein S19 | -0.0208981 |
| ETV6 | ets variant 6 | -0.0208326 |
| SGO2 | shugoshin 2 | -0.0200223 |
| MIDN | midnolin | -0.0197567 |
| RSF1 | remodeling and spacing factor 1 | -0.0193946 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0191817 |
| LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | -0.0191394 |
| RPS21 | ribosomal protein S21 | -0.0188995 |
| PHF20 | PHD finger protein 20 | -0.0188337 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0187765 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0186792 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0186231 |
| GPSM2 | G-protein signaling modulator 2 | -0.0186147 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0185777 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0183768 |
| RPL18 | ribosomal protein L18 | -0.0183027 |
| THOC2 | THO complex 2 | -0.018279 |
| NLGN1 | neuroligin 1 | -0.0182612 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0180246 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0178834 |
| LOXL2 | lysyl oxidase-like 2 | -0.0178706 |
| CDK17 | cyclin-dependent kinase 17 | -0.0177777 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0177695 |
| FMN1 | formin 1 | -0.0175251 |
| RPL36 | ribosomal protein L36 | -0.0174306 |
| SEC61G | Sec61 gamma subunit | -0.0174075 |
