| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gemcitabine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.192927 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.160224 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.157684 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.149981 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.146404 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.120114 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.100424 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0858144 |
| SQSTM1 | sequestosome 1 | 0.084675 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0835063 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0826075 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0824205 |
| TXNRD1 | thioredoxin reductase 1 | 0.0795345 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0779053 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0760671 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0754967 |
| DSPP | dentin sialophosphoprotein | 0.0746263 |
| LAMC2 | laminin, gamma 2 | 0.0735287 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0720404 |
| HSPA8 | heat shock 70kDa protein 8 | 0.07156 |
| CANX | calnexin | 0.0694154 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0646743 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0642516 |
| ENO1 | enolase 1, (alpha) | 0.062913 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0623445 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0609629 |
| SMAD3 | SMAD family member 3 | 0.0603885 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0583454 |
| CALR | calreticulin | 0.0578891 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0571412 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0555419 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0533802 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.051518 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0512003 |
| PLEC | plectin | 0.0495212 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0492812 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0488571 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0487563 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0480421 |
| TJP1 | tight junction protein 1 | 0.0474361 |
| MYO6 | myosin VI | 0.0471071 |
| CD109 | CD109 molecule | 0.0466446 |
| PCBP2 | poly(rC) binding protein 2 | 0.0465144 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0464136 |
| DST | dystonin | 0.0464002 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0461325 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0458053 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0456554 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0454146 |
| TPM3 | tropomyosin 3 | 0.0451094 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0449986 |
| FHIT | fragile histidine triad | 0.0449745 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0447829 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0447089 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0446046 |
| MYO5B | myosin VB | 0.0443186 |
| MYOF | myoferlin | 0.0440816 |
| MYO10 | myosin X | 0.0434361 |
| PKM | pyruvate kinase, muscle | 0.0432562 |
| APP | amyloid beta (A4) precursor protein | 0.0431248 |
| EZR | ezrin | 0.0427204 |
| RPL4 | ribosomal protein L4 | 0.0421399 |
| SGMS2 | sphingomyelin synthase 2 | 0.0418657 |
| MCL1 | myeloid cell leukemia 1 | 0.0416547 |
| GOLGB1 | golgin B1 | 0.041532 |
| RPS12 | ribosomal protein S12 | 0.0413577 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.041234 |
| AREG | amphiregulin | 0.0408328 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0397915 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0396396 |
| TUFT1 | tuftelin 1 | 0.0396264 |
| SPAG9 | sperm associated antigen 9 | 0.0395701 |
| RACK1 | receptor for activated C kinase 1 | 0.0395528 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0384621 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.038435 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0380337 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0378125 |
| PTK2 | protein tyrosine kinase 2 | 0.0362345 |
| ERBIN | erbb2 interacting protein | 0.0362286 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0355064 |
| RPS3 | ribosomal protein S3 | 0.035273 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0351871 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0351451 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0346516 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.034246 |
| USP53 | ubiquitin specific peptidase 53 | 0.0341499 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0341104 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0340784 |
| MED13 | mediator complex subunit 13 | 0.0339216 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.033841 |
| HDAC9 | histone deacetylase 9 | 0.0338391 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0337161 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0335189 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.033515 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0334981 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0332855 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0327067 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0327032 |
| SERINC5 | serine incorporator 5 | 0.0326523 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0320198 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.179669 |
| TMSB10 | thymosin beta 10 | -0.150713 |
| PTMA | prothymosin, alpha | -0.130296 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.116549 |
| FTL | ferritin, light polypeptide | -0.101758 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0749067 |
| NDRG1 | N-myc downstream regulated 1 | -0.0711014 |
| S100A6 | S100 calcium binding protein A6 | -0.0655712 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0570739 |
| S100A10 | S100 calcium binding protein A10 | -0.0565537 |
| PGK1 | phosphoglycerate kinase 1 | -0.0552797 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.05125 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0511915 |
| FAM162A | family with sequence similarity 162, member A | -0.0484068 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0469754 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0449357 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0436985 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0395856 |
| GNAS | GNAS complex locus | -0.0389212 |
| RPL35A | ribosomal protein L35a | -0.0383925 |
| CSTB | cystatin B (stefin B) | -0.0363851 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0359287 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0343439 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0338793 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0323686 |
| CCND1 | cyclin D1 | -0.0318265 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0316571 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0312198 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0298642 |
| FAM3C | family with sequence similarity 3, member C | -0.0296023 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0293793 |
| ACTG1 | actin gamma 1 | -0.0291657 |
| TMEM263 | transmembrane protein 263 | -0.0287833 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0278906 |
| RPS19 | ribosomal protein S19 | -0.0278509 |
| MT2A | metallothionein 2A | -0.0269443 |
| HMGA1 | high mobility group AT-hook 1 | -0.0264843 |
| TMEM165 | transmembrane protein 165 | -0.026176 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.025995 |
| HLA-B | major histocompatibility complex, class I, B | -0.0256585 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0252941 |
| CTSD | cathepsin D | -0.0252023 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0251419 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0248888 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0246231 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0245307 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0237753 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0228051 |
| RPL8 | ribosomal protein L8 | -0.0226096 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0213192 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0209654 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0209375 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.020737 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0206739 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0205191 |
| TMEM123 | transmembrane protein 123 | -0.0204809 |
| RPS21 | ribosomal protein S21 | -0.0198548 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0197962 |
| ASPH | aspartate beta-hydroxylase | -0.0194095 |
| RPLP2 | ribosomal protein, large, P2 | -0.0193303 |
| UBC | ubiquitin C | -0.0192929 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0192386 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0191474 |
| S100A11 | S100 calcium binding protein A11 | -0.018904 |
| PLAUR | plasminogen activator, urokinase receptor | -0.018805 |
| RPS15 | ribosomal protein S15 | -0.0183379 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0180913 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.017972 |
| RPL34 | ribosomal protein L34 | -0.0178357 |
| RPS29 | ribosomal protein S29 | -0.0177442 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0177257 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0176938 |
| CD2AP | CD2-associated protein | -0.017569 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0169831 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.016904 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0168686 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0168618 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0168278 |
| RRBP1 | ribosome binding protein 1 | -0.0165874 |
| PFN1 | profilin 1 | -0.0165579 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0164573 |
| TFG | TRK-fused gene | -0.0164562 |
| RPL36AL | ribosomal protein L36a-like | -0.0163694 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0161994 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0158908 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0158517 |
| RPL28 | ribosomal protein L28 | -0.015803 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0157822 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0156902 |
| BCL2L1 | BCL2-like 1 | -0.015638 |
| WTAP | Wilms tumor 1 associated protein | -0.015638 |
| FBXO34 | F-box protein 34 | -0.0154235 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.015387 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0151994 |
| MXD1 | MAX dimerization protein 1 | -0.0151862 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0149282 |
| RPL36 | ribosomal protein L36 | -0.0148931 |
| H1-0 | H1.0 linker histone | -0.0148563 |
| S100A9 | S100 calcium binding protein A9 | -0.0145869 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0144259 |
