| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GDA | guanine deaminase | 0.12785 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.117971 |
| PDLIM5 | PDZ and LIM domain 5 | 0.114867 |
| MYOF | myoferlin | 0.114778 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.101686 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0961173 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0870513 |
| SQSTM1 | sequestosome 1 | 0.0857048 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0851122 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0696765 |
| KYNU | kynureninase | 0.0682564 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.067288 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0670561 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.063458 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.063366 |
| VIM | vimentin | 0.0602885 |
| CDH13 | cadherin 13 | 0.0602475 |
| CANX | calnexin | 0.0568601 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0510059 |
| STC2 | stanniocalcin 2 | 0.0506579 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0501767 |
| FMNL2 | formin-like 2 | 0.0486296 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0485223 |
| ENO1 | enolase 1, (alpha) | 0.0477343 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0473322 |
| LDHA | lactate dehydrogenase A | 0.0467197 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0465545 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0457041 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0451733 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0437156 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.043401 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0393519 |
| NTN4 | netrin 4 | 0.0392132 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0385967 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0377075 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0367914 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0364669 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0361308 |
| CD44 | CD44 molecule (Indian blood group) | 0.0345879 |
| COL4A6 | collagen, type IV, alpha 6 | 0.03407 |
| PKM | pyruvate kinase, muscle | 0.0337229 |
| RASAL2 | RAS protein activator like 2 | 0.0336554 |
| LSAMP | limbic system-associated membrane protein | 0.0331362 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0328247 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0327023 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0325418 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0321129 |
| TMEM178B | transmembrane protein 178B | 0.0317895 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0310134 |
| INTS6 | integrator complex subunit 6 | 0.0308994 |
| XYLT1 | xylosyltransferase I | 0.0300459 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0297878 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0297519 |
| EGFR | epidermal growth factor receptor | 0.0289701 |
| TENM3 | teneurin transmembrane protein 3 | 0.0288144 |
| SMAD3 | SMAD family member 3 | 0.0284816 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0284174 |
| AUTS2 | autism susceptibility candidate 2 | 0.0283286 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0282153 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0280645 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0280344 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.027699 |
| TXNRD1 | thioredoxin reductase 1 | 0.0276851 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0275627 |
| CD109 | CD109 molecule | 0.0274107 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0261091 |
| RPS12 | ribosomal protein S12 | 0.026105 |
| RANBP17 | RAN binding protein 17 | 0.0260036 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0259185 |
| CALR | calreticulin | 0.0258994 |
| RPL4 | ribosomal protein L4 | 0.0255303 |
| INHBA | inhibin, beta A | 0.0254482 |
| MB21D2 | Mab-21 domain containing 2 | 0.0254476 |
| PCBP2 | poly(rC) binding protein 2 | 0.0254471 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0254464 |
| HYOU1 | hypoxia up-regulated 1 | 0.0252789 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0250428 |
| SVIL | supervillin | 0.0248885 |
| SEPTIN9 | septin 9 | 0.0247802 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0247216 |
| GPHN | gephyrin | 0.024284 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0238403 |
| RACK1 | receptor for activated C kinase 1 | 0.0237494 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0235495 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0234995 |
| PRKCA | protein kinase C, alpha | 0.0234441 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0233612 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0232031 |
| ATXN1 | ataxin 1 | 0.0230099 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0229955 |
| RPLP0 | ribosomal protein, large, P0 | 0.0229687 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0225973 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0225756 |
| FAT1 | FAT atypical cadherin 1 | 0.0222452 |
| TENM2 | teneurin transmembrane protein 2 | 0.0222054 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0221714 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0220405 |
| RPS6 | ribosomal protein S6 | 0.0220359 |
| FNIP1 | folliculin interacting protein 1 | 0.021341 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0212079 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.268657 |
| PTMA | prothymosin, alpha | -0.140582 |
| PDE10A | phosphodiesterase 10A | -0.133784 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130042 |
| TMSB10 | thymosin beta 10 | -0.121488 |
| EFNA5 | ephrin-A5 | -0.120113 |
| GRAMD1B | GRAM domain containing 1B | -0.113365 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0979056 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.097296 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0800266 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0776173 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.077249 |
| ASPH | aspartate beta-hydroxylase | -0.0761249 |
| COL5A2 | collagen, type V, alpha 2 | -0.0631084 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0602828 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0601598 |
| NEK7 | NIMA-related kinase 7 | -0.0586945 |
| CENPF | centromere protein F, 350/400kDa | -0.0573029 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0572758 |
| OGA | O-GlcNAcase | -0.0569009 |
| NDRG1 | N-myc downstream regulated 1 | -0.0560207 |
| RTN4 | reticulon 4 | -0.0557294 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0552925 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0550159 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0549438 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0542542 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0539282 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0520987 |
| RBM39 | RNA binding motif protein 39 | -0.0510468 |
| RGS2 | regulator of G-protein signaling 2 | -0.0507591 |
| TBXT | T-box transcription factor T | -0.0506695 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0496467 |
| PCBP3 | poly(rC) binding protein 3 | -0.048602 |
| RPL35A | ribosomal protein L35a | -0.0477783 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0470867 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0468307 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0467724 |
| RPS21 | ribosomal protein S21 | -0.0467085 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0457224 |
| RPL38 | ribosomal protein L38 | -0.0449469 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0434872 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0431874 |
| GNAS | GNAS complex locus | -0.0423397 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0419806 |
| MFF | mitochondrial fission factor | -0.041813 |
| RPLP1 | ribosomal protein, large, P1 | -0.0413729 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0405788 |
| SPAG9 | sperm associated antigen 9 | -0.040515 |
| SRGN | serglycin | -0.0393001 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0390631 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0387332 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0386983 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0386487 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0380618 |
| SRPK2 | SRSF protein kinase 2 | -0.0366856 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0364951 |
| RPL19 | ribosomal protein L19 | -0.0356568 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0356297 |
| NRCAM | neuronal cell adhesion molecule | -0.0351524 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0349171 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0340554 |
| ZNF292 | zinc finger protein 292 | -0.0339083 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0331435 |
| MKI67 | marker of proliferation Ki-67 | -0.0330082 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.032962 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0329247 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0328678 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0328651 |
| FAM13A | family with sequence similarity 13, member A | -0.0327459 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0322749 |
| PTGR1 | prostaglandin reductase 1 | -0.0318849 |
| RPL36 | ribosomal protein L36 | -0.0318674 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0312829 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0312468 |
| DOCK4 | dedicator of cytokinesis 4 | -0.031077 |
| FLNB | filamin B, beta | -0.031029 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0305959 |
| GPRIN3 | GPRIN family member 3 | -0.0305682 |
| YBX3 | Y box binding protein 3 | -0.0303832 |
| GPC6 | glypican 6 | -0.0303269 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0302998 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.030258 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0296106 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0295394 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0285404 |
| RPS13 | ribosomal protein S13 | -0.0284078 |
| RAI1 | retinoic acid induced 1 | -0.02826 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0282459 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0282107 |
| ANLN | anillin, actin binding protein | -0.0281342 |
| PGK1 | phosphoglycerate kinase 1 | -0.0280817 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0280167 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0279135 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0278868 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0277226 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0275852 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0275512 |
| RPL9 | ribosomal protein L9 | -0.027409 |
| WDR45B | WD repeat domain 45B | -0.0273557 |
| RPS27A | ribosomal protein S27a | -0.0272005 |
