| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gemcitabine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.132486 |
| USP34 | ubiquitin specific peptidase 34 | 0.124519 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.12442 |
| RUNX1 | runt-related transcription factor 1 | 0.11275 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.111002 |
| RPS16 | ribosomal protein S16 | 0.108746 |
| TXNRD1 | thioredoxin reductase 1 | 0.100782 |
| RPLP1 | ribosomal protein, large, P1 | 0.0967591 |
| RPS6 | ribosomal protein S6 | 0.0878088 |
| RPS3 | ribosomal protein S3 | 0.0809052 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.079826 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0771593 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0750852 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0707029 |
| RPS12 | ribosomal protein S12 | 0.0698315 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0693859 |
| RPL11 | ribosomal protein L11 | 0.0686959 |
| ENO1 | enolase 1, (alpha) | 0.0683914 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0681177 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0667461 |
| RPL35A | ribosomal protein L35a | 0.063094 |
| FTL | ferritin, light polypeptide | 0.0593256 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0585038 |
| RPLP0 | ribosomal protein, large, P0 | 0.0583166 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.056252 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0554626 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0550003 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0538698 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0520952 |
| CDK6 | cyclin-dependent kinase 6 | 0.0516457 |
| RPLP2 | ribosomal protein, large, P2 | 0.0514302 |
| JMJD1C | jumonji domain containing 1C | 0.0508225 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0507962 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0504427 |
| PKM | pyruvate kinase, muscle | 0.0503533 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0498264 |
| RPL4 | ribosomal protein L4 | 0.0495408 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0487973 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0485102 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0476056 |
| RPL19 | ribosomal protein L19 | 0.0459863 |
| DTNA | dystrobrevin, alpha | 0.0446797 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0440479 |
| ABI1 | abl-interactor 1 | 0.0440157 |
| FNDC3A | fibronectin type III domain containing 3A | 0.043841 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0428371 |
| RPS17 | ribosomal protein S17 | 0.0428198 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0425733 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0424232 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0421436 |
| SEPTIN9 | septin 9 | 0.041935 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0417613 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0414763 |
| RPS27 | ribosomal protein S27 | 0.0409475 |
| PHF14 | PHD finger protein 14 | 0.040939 |
| SBF2 | SET binding factor 2 | 0.0406479 |
| LMO7 | LIM domain 7 | 0.0403797 |
| ADAR | adenosine deaminase, RNA-specific | 0.0403417 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.04028 |
| DENND1A | DENN/MADD domain containing 1A | 0.0402203 |
| RPS20 | ribosomal protein S20 | 0.0397086 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0394307 |
| NAV2 | neuron navigator 2 | 0.0394159 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0390611 |
| KIF13A | kinesin family member 13A | 0.0383984 |
| KLHL29 | kelch-like family member 29 | 0.037483 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0371909 |
| EXOC6B | exocyst complex component 6B | 0.0369761 |
| ETNK1 | ethanolamine kinase 1 | 0.0355616 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0348014 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0345868 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0344736 |
| MSR1 | macrophage scavenger receptor 1 | 0.0341715 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0337958 |
| RPL37 | ribosomal protein L37 | 0.0336344 |
| TPR | translocated promoter region, nuclear basket protein | 0.0333868 |
| SH3D19 | SH3 domain containing 19 | 0.0333848 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0329966 |
| RPL26 | ribosomal protein L26 | 0.0329425 |
| CADPS | Ca++-dependent secretion activator | 0.0327757 |
| EZR | ezrin | 0.0326482 |
| B2M | beta-2-microglobulin | 0.0325171 |
| APP | amyloid beta (A4) precursor protein | 0.032517 |
| RPS8 | ribosomal protein S8 | 0.0325017 |
| ANO6 | anoctamin 6 | 0.0318034 |
| RACK1 | receptor for activated C kinase 1 | 0.0317805 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0317434 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0316091 |
| RPL37A | ribosomal protein L37a | 0.0315354 |
| RPL5 | ribosomal protein L5 | 0.0311957 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0311775 |
| HDAC4 | histone deacetylase 4 | 0.031172 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0304596 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0303574 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.029971 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0294146 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0293475 |
| DST | dystonin | 0.0292115 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0285229 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0283453 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.266956 |
| NDRG1 | N-myc downstream regulated 1 | -0.146694 |
| VIM | vimentin | -0.128425 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.1203 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.117636 |
| FN1 | fibronectin 1 | -0.110232 |
| CDH13 | cadherin 13 | -0.0845906 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0816845 |
| TMSB10 | thymosin beta 10 | -0.0795354 |
| EFNA5 | ephrin-A5 | -0.0788883 |
| GPC6 | glypican 6 | -0.0774439 |
| EGR1 | early growth response 1 | -0.0756919 |
| PRKCA | protein kinase C, alpha | -0.0694202 |
| LAMA4 | laminin, alpha 4 | -0.0693489 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0683417 |
| LAMC2 | laminin, gamma 2 | -0.0674453 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0665299 |
| HMGA2 | high mobility group AT-hook 2 | -0.0642805 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0639804 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0638945 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0631441 |
| PARD3 | par-3 family cell polarity regulator | -0.0617069 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0610949 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0597591 |
| ACTG1 | actin gamma 1 | -0.0592156 |
| LAMB3 | laminin, beta 3 | -0.058217 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0581857 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0580608 |
| FHIT | fragile histidine triad | -0.0571238 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0568117 |
| HDAC9 | histone deacetylase 9 | -0.0562244 |
| HDLBP | high density lipoprotein binding protein | -0.0552693 |
| COL5A1 | collagen, type V, alpha 1 | -0.0545222 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0539233 |
| RAD51B | RAD51 paralog B | -0.0534332 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0527978 |
| TJP1 | tight junction protein 1 | -0.0522458 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0521999 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0520789 |
| RPL15 | ribosomal protein L15 | -0.0509371 |
| FAM13A | family with sequence similarity 13, member A | -0.050119 |
| MYOF | myoferlin | -0.0498837 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.049459 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0492485 |
| YAP1 | Yes-associated protein 1 | -0.0491972 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0491298 |
| PTK2 | protein tyrosine kinase 2 | -0.0477108 |
| MYO1E | myosin IE | -0.0474583 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0473164 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0461579 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0452882 |
| TMEM165 | transmembrane protein 165 | -0.0450852 |
| NFIA | nuclear factor I/A | -0.0444652 |
| TENM3 | teneurin transmembrane protein 3 | -0.044434 |
| ANTXR2 | anthrax toxin receptor 2 | -0.044066 |
| USP3 | ubiquitin specific peptidase 3 | -0.0431065 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0424296 |
| CLTC | clathrin, heavy chain (Hc) | -0.0422995 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.041791 |
| RTN4 | reticulon 4 | -0.0411379 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0403233 |
| CALU | calumenin | -0.0393508 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0391822 |
| OLA1 | Obg-like ATPase 1 | -0.0378615 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0373626 |
| PRELID2 | PRELI domain containing 2 | -0.0372888 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0372682 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0366948 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0366606 |
| COL1A1 | collagen, type I, alpha 1 | -0.0366223 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0356388 |
| TPD52 | tumor protein D52 | -0.0351688 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0347148 |
| MYO10 | myosin X | -0.0344067 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0343975 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0342025 |
| PCBP2 | poly(rC) binding protein 2 | -0.03384 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0336155 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0335247 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0331486 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0330923 |
| AREG | amphiregulin | -0.0328703 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0328092 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0326353 |
| SETD5 | SET domain containing 5 | -0.0325453 |
| CDK13 | cyclin-dependent kinase 13 | -0.0323988 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0319135 |
| PDE10A | phosphodiesterase 10A | -0.0318969 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0316592 |
| RPL32 | ribosomal protein L32 | -0.0315427 |
| RORA | RAR-related orphan receptor A | -0.0314173 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0313661 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0306087 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0303397 |
| RBM25 | RNA binding motif protein 25 | -0.03 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0297768 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0297462 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.029626 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0295127 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.029453 |