| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0808983 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0807872 |
| QKI | QKI, KH domain containing, RNA binding | 0.0774949 |
| HDAC9 | histone deacetylase 9 | 0.075012 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0685989 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0651999 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0633124 |
| PKM | pyruvate kinase, muscle | 0.0606627 |
| ZNF292 | zinc finger protein 292 | 0.0600989 |
| EZR | ezrin | 0.0535315 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0528716 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0516114 |
| RPL26 | ribosomal protein L26 | 0.0507456 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0502804 |
| RPS3 | ribosomal protein S3 | 0.0492164 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.048476 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0481639 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0470538 |
| ENO1 | enolase 1, (alpha) | 0.0458612 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0450687 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0449213 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0444713 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0444363 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0442574 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0434485 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0420703 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.039041 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0388799 |
| MYOF | myoferlin | 0.0386972 |
| YAP1 | Yes-associated protein 1 | 0.0385742 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0383692 |
| TMSB4X | thymosin beta 4, X-linked | 0.0382638 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0371149 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0371025 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0358511 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0357555 |
| CDC73 | cell division cycle 73 | 0.0356198 |
| AFF4 | AF4/FMR2 family, member 4 | 0.035211 |
| RTN4 | reticulon 4 | 0.0351867 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0350782 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0347475 |
| RNF145 | ring finger protein 145 | 0.0346973 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0343629 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0328517 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0325179 |
| RPL37A | ribosomal protein L37a | 0.0318034 |
| MED13 | mediator complex subunit 13 | 0.0309718 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0309358 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0308977 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0308528 |
| RPS17 | ribosomal protein S17 | 0.0305852 |
| RASA2 | RAS p21 protein activator 2 | 0.0304497 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0300552 |
| TXNIP | thioredoxin interacting protein | 0.0296404 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0295124 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0294813 |
| CRY1 | cryptochrome circadian clock 1 | 0.0292117 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0291551 |
| DENND5A | DENN/MADD domain containing 5A | 0.0290645 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0286888 |
| PDGFC | platelet derived growth factor C | 0.0286673 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0286513 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0285874 |
| RPL4 | ribosomal protein L4 | 0.0284977 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0283509 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0282464 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0282395 |
| OGA | O-GlcNAcase | 0.0282167 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0275827 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.027532 |
| CORO1C | coronin, actin binding protein, 1C | 0.0274078 |
| RPS12 | ribosomal protein S12 | 0.0273482 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0273273 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0272195 |
| POU2F1 | POU class 2 homeobox 1 | 0.0271248 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0270042 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0269773 |
| TSC22D2 | TSC22 domain family, member 2 | 0.026964 |
| NUP58 | nucleoporin 58 | 0.0269555 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0269517 |
| RLF | rearranged L-myc fusion | 0.0269332 |
| EVI5 | ecotropic viral integration site 5 | 0.0266796 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0263873 |
| SIK3 | SIK family kinase 3 | 0.0263532 |
| RAB18 | RAB18, member RAS oncogene family | 0.0262396 |
| MATR3 | matrin 3 | 0.025782 |
| ATXN2 | ataxin 2 | 0.0256298 |
| PTK2 | protein tyrosine kinase 2 | 0.025577 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0255722 |
| SMAD3 | SMAD family member 3 | 0.0255325 |
| PGK1 | phosphoglycerate kinase 1 | 0.0253535 |
| LIMD1 | LIM domains containing 1 | 0.0252998 |
| NUP153 | nucleoporin 153kDa | 0.0251628 |
| RYBP | RING1 and YY1 binding protein | 0.0250526 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0250053 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0249899 |
| ATOSA | atos homolog A | 0.0249198 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0249124 |
| SLMAP | sarcolemma associated protein | 0.0249085 |
| ZNF148 | zinc finger protein 148 | 0.0249044 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.388251 |
| PTMA | prothymosin, alpha | -0.171619 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.165932 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.113547 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0987472 |
| ACTG1 | actin gamma 1 | -0.0983239 |
| BMP10 | bone morphogenetic protein 10 | -0.0882457 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0839836 |
| CCND1 | cyclin D1 | -0.0788986 |
| VCL | vinculin | -0.0786266 |
| FOXP1 | forkhead box P1 | -0.0782403 |
| AHNAK | AHNAK nucleoprotein | -0.0761207 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.072722 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0652353 |
| PFN1 | profilin 1 | -0.0642005 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0591017 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0536058 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0529921 |
| DIAPH2 | diaphanous-related formin 2 | -0.0502747 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0477553 |
| GLI3 | GLI family zinc finger 3 | -0.0472908 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0461609 |
| RPS23 | ribosomal protein S23 | -0.0458527 |
| NFIA | nuclear factor I/A | -0.0451877 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.044528 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0439748 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0425359 |
| NBEA | neurobeachin | -0.042389 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0423624 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0422776 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0422257 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0395776 |
| S100A4 | S100 calcium binding protein A4 | -0.039242 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0390885 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0385729 |
| SMYD3 | SET and MYND domain containing 3 | -0.0384123 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0377803 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0372897 |
| SBF2 | SET binding factor 2 | -0.03584 |
| GPHN | gephyrin | -0.0348624 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0341307 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0334707 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0328478 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0320213 |
| FBLN2 | fibulin 2 | -0.0317026 |
| S100A10 | S100 calcium binding protein A10 | -0.0316458 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0313772 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0313251 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0310479 |
| S100A6 | S100 calcium binding protein A6 | -0.0308688 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0302771 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.030041 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0295828 |
| ASTN2 | astrotactin 2 | -0.0287402 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0285014 |
| ARHGAP25 | Rho GTPase activating protein 25 | -0.0280443 |
| RPS15 | ribosomal protein S15 | -0.0279802 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0277632 |
| RPS21 | ribosomal protein S21 | -0.0276984 |
| POTEF | POTE ankyrin domain family, member F | -0.0276207 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0275297 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0274933 |
| S100A9 | S100 calcium binding protein A9 | -0.027368 |
| PATJ | PATJ crumbs cell polarity complex component | -0.027213 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.026534 |
| PRDX2 | peroxiredoxin 2 | -0.0264302 |
| RPL27A | ribosomal protein L27a | -0.0262942 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0261901 |
| MKI67 | marker of proliferation Ki-67 | -0.0260625 |
| TOB1 | transducer of ERBB2, 1 | -0.0260449 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0259165 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0255234 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0253459 |
| EXOC6B | exocyst complex component 6B | -0.0251627 |
| CCNI | cyclin I | -0.0250892 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0250807 |
| RPL12 | ribosomal protein L12 | -0.0249551 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0249399 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0248798 |
| RPS19 | ribosomal protein S19 | -0.0248594 |
| PMP22 | peripheral myelin protein 22 | -0.0244681 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0244122 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0243374 |
| RPS29 | ribosomal protein S29 | -0.0241992 |
| RPLP0 | ribosomal protein, large, P0 | -0.0238919 |
| SRPK2 | SRSF protein kinase 2 | -0.0238148 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0237034 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0230453 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.0227624 |
| PRELID2 | PRELI domain containing 2 | -0.0226996 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0226859 |
| HJURP | Holliday junction recognition protein | -0.0226728 |
| PYGB | phosphorylase, glycogen; brain | -0.0225483 |
| PDE7B | phosphodiesterase 7B | -0.0224917 |
| RPL28 | ribosomal protein L28 | -0.0224411 |
| RPL32 | ribosomal protein L32 | -0.0223424 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0222524 |
| RPS6 | ribosomal protein S6 | -0.0219715 |
| RPL21 | ribosomal protein L21 | -0.0219656 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0215938 |
