| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.183104 |
| CADM1 | cell adhesion molecule 1 | 0.148215 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.147968 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.119893 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.114713 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.11459 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.112364 |
| LDHA | lactate dehydrogenase A | 0.104449 |
| HDAC9 | histone deacetylase 9 | 0.103734 |
| STC2 | stanniocalcin 2 | 0.100302 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0980971 |
| CALR | calreticulin | 0.0918469 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0879745 |
| SMAD3 | SMAD family member 3 | 0.0861041 |
| VEGFA | vascular endothelial growth factor A | 0.0852153 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0826397 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0809318 |
| SQSTM1 | sequestosome 1 | 0.0788428 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0751844 |
| B2M | beta-2-microglobulin | 0.0742012 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0721955 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0720944 |
| SFTPA2 | surfactant protein A2 | 0.0695096 |
| ADM | adrenomedullin | 0.0687054 |
| CD44 | CD44 molecule (Indian blood group) | 0.068331 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0678471 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0667726 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.064883 |
| APP | amyloid beta (A4) precursor protein | 0.063369 |
| ENO1 | enolase 1, (alpha) | 0.0632245 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0604582 |
| CANX | calnexin | 0.057919 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0569738 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0568664 |
| VCAN | versican | 0.0562557 |
| FRMD4A | FERM domain containing 4A | 0.0535124 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0527954 |
| NAV2 | neuron navigator 2 | 0.0488616 |
| ARRDC3 | arrestin domain containing 3 | 0.0482791 |
| RPS12 | ribosomal protein S12 | 0.0473431 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0468121 |
| HLA-E | major histocompatibility complex, class I, E | 0.0441292 |
| FAM107B | family with sequence similarity 107, member B | 0.0423053 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0416859 |
| SNX9 | sorting nexin 9 | 0.0412826 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0412661 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0406733 |
| PCBP2 | poly(rC) binding protein 2 | 0.0401996 |
| HLA-A | major histocompatibility complex, class I, A | 0.0399822 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0389697 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.038765 |
| RPS2 | ribosomal protein S2 | 0.0386026 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0382307 |
| RUNX2 | runt-related transcription factor 2 | 0.038037 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.037603 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0364539 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0361979 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0355653 |
| RPL7A | ribosomal protein L7a | 0.0349989 |
| HPCAL1 | hippocalcin-like 1 | 0.0349212 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0346542 |
| CLTC | clathrin, heavy chain (Hc) | 0.034499 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0338776 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0337093 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0335485 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0334042 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0333338 |
| TPM3 | tropomyosin 3 | 0.0328325 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0326924 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0323537 |
| FLNA | filamin A, alpha | 0.0322139 |
| RPL4 | ribosomal protein L4 | 0.0318357 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0314429 |
| GOLGB1 | golgin B1 | 0.0313212 |
| OPTN | optineurin | 0.0312927 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0312276 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0311886 |
| PKM | pyruvate kinase, muscle | 0.0310396 |
| TMF1 | TATA element modulatory factor 1 | 0.0310204 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0307339 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0304246 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0303454 |
| IPO7 | importin 7 | 0.0300596 |
| ATF3 | activating transcription factor 3 | 0.029853 |
| RPL3 | ribosomal protein L3 | 0.029821 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0297493 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0296535 |
| SLK | STE20-like kinase | 0.0295101 |
| TXNRD1 | thioredoxin reductase 1 | 0.0288319 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0288246 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0286739 |
| PGM3 | phosphoglucomutase 3 | 0.0286729 |
| JMJD1C | jumonji domain containing 1C | 0.0286711 |
| CEP250 | centrosomal protein 250kDa | 0.028375 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0283365 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.02799 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0279721 |
| COPA | coatomer protein complex, subunit alpha | 0.0275854 |
| SPAG9 | sperm associated antigen 9 | 0.0275276 |
| USP34 | ubiquitin specific peptidase 34 | 0.0275011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.17573 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.164254 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.152611 |
| VIM | vimentin | -0.136409 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.109421 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.104087 |
| VCL | vinculin | -0.101589 |
| GLIS3 | GLIS family zinc finger 3 | -0.0957011 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0952562 |
| FN1 | fibronectin 1 | -0.0918624 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0895068 |
| FTL | ferritin, light polypeptide | -0.082366 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0730604 |
| PGK1 | phosphoglycerate kinase 1 | -0.0711508 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0707861 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0626922 |
| DIAPH2 | diaphanous-related formin 2 | -0.0570917 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0561992 |
| NDRG1 | N-myc downstream regulated 1 | -0.055674 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0556022 |
| PTMA | prothymosin, alpha | -0.0542707 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0538679 |
| PDE10A | phosphodiesterase 10A | -0.0532091 |
| GNAS | GNAS complex locus | -0.0524189 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0508071 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0498828 |
| TENM2 | teneurin transmembrane protein 2 | -0.0485995 |
| RPS21 | ribosomal protein S21 | -0.0478843 |
| ACTG1 | actin gamma 1 | -0.0474648 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0464743 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0458976 |
| RPL19 | ribosomal protein L19 | -0.0449667 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0441363 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.043947 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0433287 |
| NAV1 | neuron navigator 1 | -0.0421479 |
| RPL35A | ribosomal protein L35a | -0.0417228 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0407333 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0375375 |
| LOX | lysyl oxidase | -0.0373966 |
| CALD1 | caldesmon 1 | -0.0371728 |
| KLF6 | Kruppel-like factor 6 | -0.0371677 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0364885 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0361295 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0354806 |
| NABP1 | nucleic acid binding protein 1 | -0.0353651 |
| PALLD | palladin, cytoskeletal associated protein | -0.0342252 |
| NRN1 | neuritin 1 | -0.0335103 |
| RTN4 | reticulon 4 | -0.0331464 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0330966 |
| RPS19 | ribosomal protein S19 | -0.0325578 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0324441 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0323923 |
| PLIN2 | perilipin 2 | -0.0323308 |
| RAI14 | retinoic acid induced 14 | -0.0308721 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0304317 |
| ANXA2 | annexin A2 | -0.0299446 |
| MT2A | metallothionein 2A | -0.029619 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.0291343 |
| WTAP | Wilms tumor 1 associated protein | -0.028736 |
| RPL38 | ribosomal protein L38 | -0.0282553 |
| RIGI | RNA sensor RIG-I | -0.0282231 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0281609 |
| GPC6 | glypican 6 | -0.027795 |
| SBF2 | SET binding factor 2 | -0.0277055 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0276163 |
| TPM1 | tropomyosin 1 (alpha) | -0.0275848 |
| PFN1 | profilin 1 | -0.0274145 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0270461 |
| WDR45B | WD repeat domain 45B | -0.0269073 |
| HMGA2 | high mobility group AT-hook 2 | -0.0265317 |
| S100A9 | S100 calcium binding protein A9 | -0.0258215 |
| RAI1 | retinoic acid induced 1 | -0.0258038 |
| ARFGEF3 | ARFGEF family member 3 | -0.0257613 |
| OSMR | oncostatin M receptor | -0.0256676 |
| OGA | O-GlcNAcase | -0.0254942 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0253927 |
| DEK | DEK proto-oncogene | -0.0253707 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0251282 |
| PRR16 | proline rich 16 | -0.0251003 |
| RPL34 | ribosomal protein L34 | -0.0250202 |
| EGR1 | early growth response 1 | -0.0247781 |
| TNNC1 | troponin C type 1 (slow) | -0.024757 |
| LRRC7 | leucine rich repeat containing 7 | -0.0242991 |
| RNF24 | ring finger protein 24 | -0.0241958 |
| RPL36 | ribosomal protein L36 | -0.0241851 |
| STK17A | serine/threonine kinase 17a | -0.0240494 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0234558 |
| RPL32 | ribosomal protein L32 | -0.0233664 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0232786 |
| RPLP1 | ribosomal protein, large, P1 | -0.0231227 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0226586 |
| ACTN4 | actinin, alpha 4 | -0.0226341 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0225269 |
| DST | dystonin | -0.022153 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0220872 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0220378 |
| AHNAK | AHNAK nucleoprotein | -0.021982 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0216545 |
| COL1A1 | collagen, type I, alpha 1 | -0.0216233 |
