| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM1 | cell adhesion molecule 1 | 0.210587 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.174768 |
| CALR | calreticulin | 0.167298 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.146852 |
| COL6A3 | collagen, type VI, alpha 3 | 0.136793 |
| B2M | beta-2-microglobulin | 0.115265 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.101303 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0912349 |
| THBS1 | thrombospondin 1 | 0.0895073 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0886522 |
| CANX | calnexin | 0.0884525 |
| STC2 | stanniocalcin 2 | 0.0868115 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0850637 |
| ARMC9 | armadillo repeat containing 9 | 0.0804037 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0761904 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.07477 |
| ARRDC3 | arrestin domain containing 3 | 0.0742853 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0730398 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0715118 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0710955 |
| ENO1 | enolase 1, (alpha) | 0.0701513 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0685261 |
| EXT1 | exostosin glycosyltransferase 1 | 0.066375 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0657843 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0644004 |
| CD44 | CD44 molecule (Indian blood group) | 0.0627424 |
| COG6 | component of oligomeric golgi complex 6 | 0.0602631 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0599198 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0569783 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0566084 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0561391 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0559332 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0556007 |
| GOLGB1 | golgin B1 | 0.0538843 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0512692 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0512244 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0509794 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.049813 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0494561 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.0486225 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0484547 |
| KYNU | kynureninase | 0.0484101 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0479432 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0477991 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0471234 |
| SQSTM1 | sequestosome 1 | 0.0462424 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0452151 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0448735 |
| ECE1 | endothelin converting enzyme 1 | 0.0441388 |
| STC1 | stanniocalcin 1 | 0.0439322 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0426705 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0414105 |
| FAM107B | family with sequence similarity 107, member B | 0.0403322 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0399764 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0392229 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0390567 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0389473 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0388854 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0379627 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0378468 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0376614 |
| PTGES2 | prostaglandin E synthase 2 | 0.0374283 |
| DSTN | destrin (actin depolymerizing factor) | 0.0368551 |
| CD109 | CD109 molecule | 0.03626 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0359805 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0357072 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0356978 |
| TPM3 | tropomyosin 3 | 0.0354631 |
| UBE3C | ubiquitin protein ligase E3C | 0.0354018 |
| VMP1 | vacuole membrane protein 1 | 0.0348693 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0348424 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0347953 |
| MYLK | myosin light chain kinase | 0.0346273 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0344631 |
| ZNF608 | zinc finger protein 608 | 0.034069 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0338887 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0334699 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0333494 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0329509 |
| CAB39 | calcium binding protein 39 | 0.032823 |
| ANO6 | anoctamin 6 | 0.0326212 |
| EREG | epiregulin | 0.0325022 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0323865 |
| PGM3 | phosphoglucomutase 3 | 0.0320606 |
| PKM | pyruvate kinase, muscle | 0.0320476 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0319766 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0316904 |
| PCBP2 | poly(rC) binding protein 2 | 0.0312609 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0311702 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0310281 |
| ADM | adrenomedullin | 0.0305818 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0302936 |
| VEGFA | vascular endothelial growth factor A | 0.0299658 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0298351 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0297854 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0293789 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0291943 |
| YIPF5 | Yip1 domain family, member 5 | 0.0291062 |
| MEF2A | myocyte enhancer factor 2A | 0.0290366 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.029035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.137652 |
| FN1 | fibronectin 1 | -0.107641 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0846447 |
| COL1A2 | collagen, type I, alpha 2 | -0.0782493 |
| MT1X | metallothionein 1X | -0.0777038 |
| PTMA | prothymosin, alpha | -0.0680712 |
| VIM | vimentin | -0.0676471 |
| MT2A | metallothionein 2A | -0.0661955 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0652997 |
| LOX | lysyl oxidase | -0.062765 |
| COL1A1 | collagen, type I, alpha 1 | -0.0620094 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.06045 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0580617 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0559206 |
| PRELID2 | PRELI domain containing 2 | -0.0534258 |
| VCL | vinculin | -0.0523215 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0520684 |
| RTN4 | reticulon 4 | -0.0482441 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0480263 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0477418 |
| HLA-B | major histocompatibility complex, class I, B | -0.0474156 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0471872 |
| CALD1 | caldesmon 1 | -0.0466439 |
| PRSS23 | protease, serine, 23 | -0.0465131 |
| H3-3B | H3.3 histone B | -0.0417048 |
| NAV1 | neuron navigator 1 | -0.0401927 |
| RPL11 | ribosomal protein L11 | -0.0389201 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0387546 |
| HMGA2 | high mobility group AT-hook 2 | -0.0387111 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0379584 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0377798 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0373693 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0368511 |
| AUTS2 | autism susceptibility candidate 2 | -0.0357339 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0353766 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0350053 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0350042 |
| MSI2 | musashi RNA-binding protein 2 | -0.0348868 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0348178 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0339783 |
| TPM1 | tropomyosin 1 (alpha) | -0.0336819 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0333824 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0326119 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0318776 |
| COL5A1 | collagen, type V, alpha 1 | -0.0317555 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0317367 |
| PRKCA | protein kinase C, alpha | -0.0312674 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0312388 |
| ACTG1 | actin gamma 1 | -0.031192 |
| TNNC1 | troponin C type 1 (slow) | -0.0311621 |
| HLA-C | major histocompatibility complex, class I, C | -0.0309929 |
| WDR45B | WD repeat domain 45B | -0.0307828 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0302856 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0299499 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0299345 |
| COL5A2 | collagen, type V, alpha 2 | -0.029594 |
| ASPH | aspartate beta-hydroxylase | -0.0294107 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0292276 |
| PDE10A | phosphodiesterase 10A | -0.0290888 |
| PFN1 | profilin 1 | -0.0290551 |
| RAI1 | retinoic acid induced 1 | -0.0289977 |
| EGR1 | early growth response 1 | -0.0288151 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0281827 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0278754 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0278451 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0277341 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0276861 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.027602 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0274834 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0274787 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0273539 |
| ETV6 | ets variant 6 | -0.0273498 |
| FAM13A | family with sequence similarity 13, member A | -0.0273418 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0273155 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0272388 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0270709 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0269121 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0265855 |
| TMEM165 | transmembrane protein 165 | -0.0265668 |
| RBM6 | RNA binding motif protein 6 | -0.0265046 |
| CENPF | centromere protein F, 350/400kDa | -0.0264759 |
| TMEM123 | transmembrane protein 123 | -0.0259658 |
| CCDC88A | coiled-coil domain containing 88A | -0.0259076 |
| CDK6 | cyclin-dependent kinase 6 | -0.0258528 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0255283 |
| SEPTIN7 | septin 7 | -0.0253317 |
| FNBP1 | formin binding protein 1 | -0.0250232 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0248726 |
| FRMD4A | FERM domain containing 4A | -0.0247977 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0247803 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0247796 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0246977 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0246966 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0245633 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0244315 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0242967 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0241313 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0241132 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0239183 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0237452 |
