| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BIRC3 | baculoviral IAP repeat containing 3 | 0.151449 |
| SQSTM1 | sequestosome 1 | 0.138362 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.117425 |
| TXNRD1 | thioredoxin reductase 1 | 0.101729 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0953784 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0920642 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0844194 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0827237 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0789767 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0780502 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0756425 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0710247 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0700943 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0634902 |
| ENO1 | enolase 1, (alpha) | 0.062892 |
| SMAD3 | SMAD family member 3 | 0.062848 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0626793 |
| INTS6 | integrator complex subunit 6 | 0.062013 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0615672 |
| EGFR | epidermal growth factor receptor | 0.0599969 |
| SVIL | supervillin | 0.0589592 |
| ANXA1 | annexin A1 | 0.0573533 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0565374 |
| ANXA2 | annexin A2 | 0.0564753 |
| IPO7 | importin 7 | 0.052228 |
| B2M | beta-2-microglobulin | 0.0520825 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0516077 |
| PKM | pyruvate kinase, muscle | 0.0504636 |
| PRKCA | protein kinase C, alpha | 0.0489761 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0467011 |
| JUN | jun proto-oncogene | 0.0464359 |
| POTEF | POTE ankyrin domain family, member F | 0.0461925 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0458766 |
| TLE4 | transducin-like enhancer of split 4 | 0.0458267 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0457328 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0454043 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0446148 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0440676 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0439164 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0437676 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.04363 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0421968 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.040875 |
| CANX | calnexin | 0.0405331 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0401148 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0399225 |
| GOLGB1 | golgin B1 | 0.0397665 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0391791 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0390479 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0388695 |
| CALR | calreticulin | 0.0381968 |
| CLDN1 | claudin 1 | 0.0377389 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0375452 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0366463 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0359537 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0358687 |
| EZR | ezrin | 0.0357761 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0356799 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0349549 |
| RPS12 | ribosomal protein S12 | 0.0348819 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.034679 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0346289 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0342242 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0342022 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0338453 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0336619 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0334564 |
| MED13 | mediator complex subunit 13 | 0.0334435 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.033208 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0329053 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0329 |
| SETX | senataxin | 0.0321912 |
| LIMA1 | LIM domain and actin binding 1 | 0.0320707 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0316923 |
| AHR | aryl hydrocarbon receptor | 0.0311555 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0310605 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0310195 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0310187 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0309723 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0308408 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0307107 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0305799 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0305265 |
| HDAC9 | histone deacetylase 9 | 0.0304513 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0303041 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0302183 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0301848 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0300577 |
| PTGES2 | prostaglandin E synthase 2 | 0.0299777 |
| CALU | calumenin | 0.0298968 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0296588 |
| CPNE8 | copine VIII | 0.0295499 |
| ASPH | aspartate beta-hydroxylase | 0.0293733 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0289456 |
| TRAM2 | translocation associated membrane protein 2 | 0.0288407 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.028836 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0282153 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0282056 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.027963 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0279551 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180453 |
| SMYD3 | SET and MYND domain containing 3 | -0.10187 |
| PRELID2 | PRELI domain containing 2 | -0.0847474 |
| RBM39 | RNA binding motif protein 39 | -0.0842006 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0836751 |
| RAD51B | RAD51 paralog B | -0.0761721 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0723276 |
| TMSB10 | thymosin beta 10 | -0.0686895 |
| VIM | vimentin | -0.0678724 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0663506 |
| NDRG1 | N-myc downstream regulated 1 | -0.0658192 |
| HMGA2 | high mobility group AT-hook 2 | -0.0621714 |
| DST | dystonin | -0.0571324 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0510006 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0498392 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0470751 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.04686 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0465314 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0464332 |
| ZNF292 | zinc finger protein 292 | -0.0463532 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0455747 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0453674 |
| OSMR | oncostatin M receptor | -0.045326 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0450342 |
| PGK1 | phosphoglycerate kinase 1 | -0.0437476 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0421717 |
| YBX3 | Y box binding protein 3 | -0.0414211 |
| PTK2 | protein tyrosine kinase 2 | -0.040779 |
| RPL35A | ribosomal protein L35a | -0.0396346 |
| DNER | delta/notch-like EGF repeat containing | -0.0395233 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0392716 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0383732 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0378529 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0376221 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0371888 |
| DSCAM | Down syndrome cell adhesion molecule | -0.037018 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0367417 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0364948 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0364129 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0362346 |
| GPC6 | glypican 6 | -0.0362318 |
| ZNF609 | zinc finger protein 609 | -0.0362179 |
| FMN1 | formin 1 | -0.0361799 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0361206 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.035373 |
| NAV2 | neuron navigator 2 | -0.0349739 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.033901 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0329046 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0327646 |
| PTMA | prothymosin, alpha | -0.0325807 |
| ACER3 | alkaline ceramidase 3 | -0.0322808 |
| RIGI | RNA sensor RIG-I | -0.0320497 |
| FMNL2 | formin-like 2 | -0.0318771 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0318682 |
| LAMA5 | laminin, alpha 5 | -0.0314852 |
| WDR45B | WD repeat domain 45B | -0.0312468 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0311263 |
| DENND1A | DENN/MADD domain containing 1A | -0.0309015 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0308862 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0308852 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0307827 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0305695 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0303402 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0302482 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0302452 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0302131 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0299996 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0296565 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0295752 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0293621 |
| SNX14 | sorting nexin 14 | -0.0292288 |
| VCL | vinculin | -0.0289881 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0283815 |
| PRSS23 | protease, serine, 23 | -0.0283454 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0280824 |
| SEPTIN7 | septin 7 | -0.0280226 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.027774 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0276054 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0275147 |
| CENPF | centromere protein F, 350/400kDa | -0.0274597 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0267986 |
| PFKP | phosphofructokinase, platelet | -0.0267151 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0266149 |
| MSN | moesin | -0.0266041 |
| YAP1 | Yes-associated protein 1 | -0.0266 |
| IGF2 | insulin-like growth factor 2 | -0.0265571 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0262037 |
| SDC4 | syndecan 4 | -0.0261934 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0256677 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0255057 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0254995 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0253323 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0252039 |
| CDK17 | cyclin-dependent kinase 17 | -0.0251543 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0251354 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0251287 |
| TPX2 | TPX2, microtubule-associated | -0.0250359 |
| HELZ | helicase with zinc finger | -0.0249792 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0249155 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0249064 |
