| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemcitabine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemcitabine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC2 | stanniocalcin 2 | 0.171145 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.115738 |
| EXT1 | exostosin glycosyltransferase 1 | 0.111508 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0900468 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0839474 |
| EREG | epiregulin | 0.0759689 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0734002 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0688915 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0659575 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0621076 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0590757 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0558407 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0550681 |
| TXNRD1 | thioredoxin reductase 1 | 0.0540368 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0538939 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0523456 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0519248 |
| MB21D2 | Mab-21 domain containing 2 | 0.0518095 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0513084 |
| GPATCH2L | G patch domain containing 2-like | 0.0509817 |
| MYOF | myoferlin | 0.0503211 |
| CALR | calreticulin | 0.0490055 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.048866 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0478452 |
| TXNIP | thioredoxin interacting protein | 0.0477872 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0475229 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0451054 |
| SMAD3 | SMAD family member 3 | 0.0449093 |
| SFTPA2 | surfactant protein A2 | 0.0432653 |
| FBN1 | fibrillin 1 | 0.0427466 |
| B2M | beta-2-microglobulin | 0.0424987 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0423362 |
| FAT1 | FAT atypical cadherin 1 | 0.0410521 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0409686 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0408878 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0406247 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0401013 |
| TMEM156 | transmembrane protein 156 | 0.0394082 |
| RASAL2 | RAS protein activator like 2 | 0.0392586 |
| ATF6 | activating transcription factor 6 | 0.0372764 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0371693 |
| AEBP2 | AE binding protein 2 | 0.0369682 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0363708 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0356318 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0351424 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0340566 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0338287 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0334646 |
| RPS25 | ribosomal protein S25 | 0.0332881 |
| CD109 | CD109 molecule | 0.0329789 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0329038 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0324436 |
| HYOU1 | hypoxia up-regulated 1 | 0.0322993 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0322926 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0320069 |
| RPS16 | ribosomal protein S16 | 0.0313591 |
| DENND5B | DENN/MADD domain containing 5B | 0.0311813 |
| AREG | amphiregulin | 0.0308741 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | 0.0304832 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0300036 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0297576 |
| SGMS2 | sphingomyelin synthase 2 | 0.0294347 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0293542 |
| ZNF638 | zinc finger protein 638 | 0.029348 |
| IL6ST | interleukin 6 signal transducer | 0.0293469 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0291304 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0290996 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0287719 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0285744 |
| MCL1 | myeloid cell leukemia 1 | 0.028375 |
| AHI1 | Abelson helper integration site 1 | 0.0283547 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0283376 |
| SIK3 | SIK family kinase 3 | 0.0282336 |
| BRD2 | bromodomain containing 2 | 0.0281606 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0281478 |
| ABLIM1 | actin binding LIM protein 1 | 0.0281471 |
| RPS23 | ribosomal protein S23 | 0.0277662 |
| DSTN | destrin (actin depolymerizing factor) | 0.0276555 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.027525 |
| SQSTM1 | sequestosome 1 | 0.027174 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0271405 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0271132 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 0.0270928 |
| SERTAD2 | SERTA domain containing 2 | 0.0267914 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0261212 |
| MED13 | mediator complex subunit 13 | 0.0261151 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0260952 |
| GPHN | gephyrin | 0.0259721 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0257889 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0257417 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0256999 |
| RBPMS | RNA binding protein with multiple splicing | 0.0256493 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0255905 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0255228 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0254951 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0254053 |
| SIRT1 | sirtuin 1 | 0.0252689 |
| EMP1 | epithelial membrane protein 1 | 0.0252304 |
| EXOC6B | exocyst complex component 6B | 0.024951 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0249023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.269071 |
| PTMA | prothymosin, alpha | -0.173655 |
| TMSB10 | thymosin beta 10 | -0.124774 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.120572 |
| NDRG1 | N-myc downstream regulated 1 | -0.116248 |
| ITGA1 | integrin, alpha 1 | -0.109761 |
| HMGA2 | high mobility group AT-hook 2 | -0.106885 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.102519 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0842535 |
| NRG1 | neuregulin 1 | -0.0791044 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0778729 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0763554 |
| GLIS3 | GLIS family zinc finger 3 | -0.0747715 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0731309 |
| MT2A | metallothionein 2A | -0.0683194 |
| OSMR | oncostatin M receptor | -0.0656204 |
| ASPH | aspartate beta-hydroxylase | -0.0630021 |
| S100A6 | S100 calcium binding protein A6 | -0.0623941 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0595853 |
| TMSB4X | thymosin beta 4, X-linked | -0.0581741 |
| ZNF292 | zinc finger protein 292 | -0.0573894 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0567371 |
| CENPF | centromere protein F, 350/400kDa | -0.0563802 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0551532 |
| H1-0 | H1.0 linker histone | -0.0550566 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0544569 |
| ACTN4 | actinin, alpha 4 | -0.0535358 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0529736 |
| PGK1 | phosphoglycerate kinase 1 | -0.0525083 |
| NRP1 | neuropilin 1 | -0.0520669 |
| FNBP1 | formin binding protein 1 | -0.0520621 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0516597 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0516512 |
| MKI67 | marker of proliferation Ki-67 | -0.0511769 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.04926 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0492059 |
| SMOX | spermine oxidase | -0.0488688 |
| ETV1 | ets variant 1 | -0.0477783 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0473981 |
| CD44 | CD44 molecule (Indian blood group) | -0.047045 |
| HLA-B | major histocompatibility complex, class I, B | -0.0469793 |
| PRELID2 | PRELI domain containing 2 | -0.0465113 |
| FAM20C | family with sequence similarity 20, member C | -0.0464015 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0455561 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.04555 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0447599 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0436527 |
| PTK2 | protein tyrosine kinase 2 | -0.0435583 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0433776 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0428855 |
| RPS27A | ribosomal protein S27a | -0.0414984 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0413092 |
| GNAS | GNAS complex locus | -0.0410504 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0410223 |
| PELO | pelota homolog (Drosophila) | -0.040966 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0409235 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0406925 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0400307 |
| OGA | O-GlcNAcase | -0.0396657 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0396029 |
| TMEM165 | transmembrane protein 165 | -0.0396015 |
| PLIN2 | perilipin 2 | -0.039552 |
| TGFA | transforming growth factor, alpha | -0.0387506 |
| RPS21 | ribosomal protein S21 | -0.0380517 |
| FAM13A | family with sequence similarity 13, member A | -0.0378219 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0377367 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0373856 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0370152 |
| AHNAK | AHNAK nucleoprotein | -0.036238 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0357348 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0353008 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0352401 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0346256 |
| ZNF217 | zinc finger protein 217 | -0.0346157 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.034507 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.033917 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0337459 |
| VIM | vimentin | -0.0333935 |
| FOXP1 | forkhead box P1 | -0.0331469 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0330416 |
| EFNA5 | ephrin-A5 | -0.0327055 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0326382 |
| WDR45B | WD repeat domain 45B | -0.0325277 |
| RBM39 | RNA binding motif protein 39 | -0.0324099 |
| VCL | vinculin | -0.0319901 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0318416 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0317705 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0315826 |
| ANLN | anillin, actin binding protein | -0.0308372 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0307922 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0305906 |
| RAD21 | RAD21 homolog (S. pombe) | -0.030525 |
| INSIG2 | insulin induced gene 2 | -0.0303162 |
| RNF145 | ring finger protein 145 | -0.030235 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0302258 |
| LOX | lysyl oxidase | -0.0300061 |
| RTN4 | reticulon 4 | -0.0296872 |
| SYT1 | synaptotagmin I | -0.0295934 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0295037 |
| CENPE | centromere protein E, 312kDa | -0.0291146 |
