| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemfibrozil_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | 0.133459 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.112294 |
| POTEF | POTE ankyrin domain family, member F | 0.107088 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.10105 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0935266 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0857299 |
| HDAC9 | histone deacetylase 9 | 0.0841681 |
| PRELID2 | PRELI domain containing 2 | 0.0775123 |
| FNDC3B | fibronectin type III domain containing 3B | 0.076741 |
| INTS6 | integrator complex subunit 6 | 0.0754433 |
| CD44 | CD44 molecule (Indian blood group) | 0.074883 |
| NAV1 | neuron navigator 1 | 0.0739263 |
| DST | dystonin | 0.0734235 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0718232 |
| MYOF | myoferlin | 0.0712166 |
| VCL | vinculin | 0.069657 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0679469 |
| MAP1B | microtubule-associated protein 1B | 0.0671442 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0667528 |
| ASPH | aspartate beta-hydroxylase | 0.0613259 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0606299 |
| EGFR | epidermal growth factor receptor | 0.0602582 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.057505 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0559558 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.054921 |
| SP100 | SP100 nuclear antigen | 0.0549125 |
| ANKRD11 | ankyrin repeat domain 11 | 0.053387 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0525268 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0500475 |
| SQSTM1 | sequestosome 1 | 0.0488934 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0486834 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0485069 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0481767 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0457138 |
| FLNA | filamin A, alpha | 0.0450441 |
| EFNA5 | ephrin-A5 | 0.0442799 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0436748 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.043196 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0430105 |
| NAV2 | neuron navigator 2 | 0.0419686 |
| LDHA | lactate dehydrogenase A | 0.0418877 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0418128 |
| RIGI | RNA sensor RIG-I | 0.0413891 |
| ERBIN | erbb2 interacting protein | 0.0412948 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0412187 |
| GOLGB1 | golgin B1 | 0.0407974 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0407736 |
| AHNAK | AHNAK nucleoprotein | 0.0404972 |
| ACTG1 | actin gamma 1 | 0.0377896 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0364379 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.036261 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0361746 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0361123 |
| ADD1 | adducin 1 (alpha) | 0.035924 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0357742 |
| CDK6 | cyclin-dependent kinase 6 | 0.0357716 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0355642 |
| NEK7 | NIMA-related kinase 7 | 0.0353118 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0350461 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0350361 |
| RASAL2 | RAS protein activator like 2 | 0.0350163 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0345983 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0342678 |
| PKM | pyruvate kinase, muscle | 0.0341383 |
| SMYD3 | SET and MYND domain containing 3 | 0.0339614 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0337316 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0334667 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0333307 |
| VEGFA | vascular endothelial growth factor A | 0.0332986 |
| COPA | coatomer protein complex, subunit alpha | 0.0332437 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0331281 |
| CENPF | centromere protein F, 350/400kDa | 0.032278 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0321973 |
| DIAPH3 | diaphanous-related formin 3 | 0.0318079 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0317595 |
| SMAD3 | SMAD family member 3 | 0.0317452 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0315489 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0314471 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0314099 |
| ATXN1 | ataxin 1 | 0.0311798 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0308289 |
| ZNF638 | zinc finger protein 638 | 0.030697 |
| TENM3 | teneurin transmembrane protein 3 | 0.0303364 |
| IPO9 | importin 9 | 0.0302551 |
| DSPP | dentin sialophosphoprotein | 0.0301269 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0301026 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0299889 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0298811 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0298385 |
| MSN | moesin | 0.0295241 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0294134 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0290862 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0290771 |
| BPTF | bromodomain PHD finger transcription factor | 0.0288321 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.028748 |
| MED13 | mediator complex subunit 13 | 0.0286831 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0284375 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0282541 |
| RRM2 | ribonucleotide reductase M2 | 0.0281354 |
| GLIS3 | GLIS family zinc finger 3 | 0.0279846 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.290147 |
| VIM | vimentin | -0.167932 |
| TMSB10 | thymosin beta 10 | -0.142355 |
| LOXL2 | lysyl oxidase-like 2 | -0.103727 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0963994 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.09266 |
| THBS2 | thrombospondin 2 | -0.0841504 |
| MT2A | metallothionein 2A | -0.0777797 |
| FBN1 | fibrillin 1 | -0.0711759 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0661092 |
| S100A6 | S100 calcium binding protein A6 | -0.0653764 |
| COL3A1 | collagen, type III, alpha 1 | -0.0586623 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0581111 |
| COL1A2 | collagen, type I, alpha 2 | -0.05684 |
| HLA-B | major histocompatibility complex, class I, B | -0.0533625 |
| NDRG1 | N-myc downstream regulated 1 | -0.0517598 |
| LOX | lysyl oxidase | -0.0515823 |
| PLAT | plasminogen activator, tissue | -0.0503235 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0500258 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0473857 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0461761 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0453553 |
| CD99 | CD99 molecule | -0.045215 |
| MT1X | metallothionein 1X | -0.0440639 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0440613 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0415457 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0413563 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0408837 |
| FLNB | filamin B, beta | -0.0370567 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0369429 |
| CSTB | cystatin B (stefin B) | -0.0368022 |
| FN1 | fibronectin 1 | -0.0356957 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0340442 |
| RAI1 | retinoic acid induced 1 | -0.0326571 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0315634 |
| MEIS2 | Meis homeobox 2 | -0.0302766 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0297426 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0287414 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0286345 |
| RNF24 | ring finger protein 24 | -0.028152 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0274688 |
| ANXA2 | annexin A2 | -0.0273648 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0272618 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0266688 |
| SUCNR1 | succinate receptor 1 | -0.0263829 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0261767 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0257566 |
| HLA-E | major histocompatibility complex, class I, E | -0.0250687 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0233212 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0229101 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0224423 |
| SBF2 | SET binding factor 2 | -0.0223764 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.021963 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0218752 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0218329 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0215579 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0213401 |
| B2M | beta-2-microglobulin | -0.0212369 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0212227 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | -0.021163 |
| MYADM | myeloid-associated differentiation marker | -0.02077 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0206997 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0198507 |
| RLF | rearranged L-myc fusion | -0.0198273 |
| CTSB | cathepsin B | -0.0197025 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0196224 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0195291 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0193097 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0190378 |
| IKBIP | IKBKB interacting protein | -0.0189652 |
| S100A4 | S100 calcium binding protein A4 | -0.0187992 |
| TMOD1 | tropomodulin 1 | -0.0187803 |
| BSG | basigin (Ok blood group) | -0.0187009 |
| S100A11 | S100 calcium binding protein A11 | -0.0186845 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0185984 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0180812 |
| FTL | ferritin, light polypeptide | -0.0180506 |
| INSIG1 | insulin induced gene 1 | -0.0180473 |
| TMSB4X | thymosin beta 4, X-linked | -0.0178266 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0177931 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0177584 |
| USP3 | ubiquitin specific peptidase 3 | -0.0177082 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0176668 |
| CLU | clusterin | -0.0174506 |
| S100A10 | S100 calcium binding protein A10 | -0.0173749 |
| TUBB6 | tubulin, beta 6 class V | -0.0172334 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0172286 |
| NGLY1 | N-glycanase 1 | -0.0170966 |
| ADM | adrenomedullin | -0.0170729 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0170697 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0168943 |
| COL5A2 | collagen, type V, alpha 2 | -0.0168162 |
| FAM162A | family with sequence similarity 162, member A | -0.016527 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0164141 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0163766 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0163117 |
| FNBP4 | formin binding protein 4 | -0.0162321 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | -0.0162043 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.016084 |
| RPS27 | ribosomal protein S27 | -0.0160698 |
