| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemfibrozil_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.377101 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.12914 |
| ANXA2 | annexin A2 | 0.119874 |
| RNF213 | ring finger protein 213 | 0.11479 |
| AREG | amphiregulin | 0.109315 |
| INTS6 | integrator complex subunit 6 | 0.108111 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0991573 |
| SMAD3 | SMAD family member 3 | 0.0947971 |
| TJP1 | tight junction protein 1 | 0.0928034 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0911108 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0858625 |
| VCL | vinculin | 0.0829603 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0826377 |
| MYO1E | myosin IE | 0.0808757 |
| PERP | PERP, TP53 apoptosis effector | 0.0772239 |
| RIGI | RNA sensor RIG-I | 0.0769116 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0744571 |
| SP100 | SP100 nuclear antigen | 0.0724637 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0692075 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0690647 |
| MX2 | MX dynamin-like GTPase 2 | 0.0689132 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0673809 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0658499 |
| ERBIN | erbb2 interacting protein | 0.0637696 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0631562 |
| EZR | ezrin | 0.0625997 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0625422 |
| PLSCR1 | phospholipid scramblase 1 | 0.0619458 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0592106 |
| EFNB2 | ephrin-B2 | 0.0574908 |
| ZNF292 | zinc finger protein 292 | 0.0564782 |
| VMP1 | vacuole membrane protein 1 | 0.0535872 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0513982 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0491711 |
| ITGA6 | integrin, alpha 6 | 0.0486645 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0461509 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0457752 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0457486 |
| TMC5 | transmembrane channel-like 5 | 0.0429505 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0426524 |
| DUSP10 | dual specificity phosphatase 10 | 0.0419745 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0417063 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0415913 |
| SQSTM1 | sequestosome 1 | 0.0409124 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0407824 |
| SIK3 | SIK family kinase 3 | 0.0407577 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0403591 |
| KYNU | kynureninase | 0.0401945 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0401575 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0395302 |
| BCL2L1 | BCL2-like 1 | 0.039426 |
| ACTG1 | actin gamma 1 | 0.0389538 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.038587 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0384185 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0379406 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0376397 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0376023 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0374344 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0373312 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.037152 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0361598 |
| DST | dystonin | 0.0358707 |
| SEPTIN9 | septin 9 | 0.0358389 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.035635 |
| CTBP2 | C-terminal binding protein 2 | 0.0354509 |
| MX1 | MX dynamin-like GTPase 1 | 0.0348925 |
| NABP1 | nucleic acid binding protein 1 | 0.0341375 |
| ETV6 | ets variant 6 | 0.0340094 |
| LAMB3 | laminin, beta 3 | 0.0328185 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0326063 |
| EGR1 | early growth response 1 | 0.0323919 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0321036 |
| MCU | mitochondrial calcium uniporter | 0.0319496 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0314766 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0310489 |
| IGF1R | insulin-like growth factor 1 receptor | 0.030252 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.030203 |
| MSI2 | musashi RNA-binding protein 2 | 0.0300621 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0297045 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0296561 |
| CDHR2 | cadherin-related family member 2 | 0.0291163 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0289341 |
| HKDC1 | hexokinase domain containing 1 | 0.0289137 |
| MYO5B | myosin VB | 0.028731 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0287212 |
| DIAPH1 | diaphanous-related formin 1 | 0.0287045 |
| UBAP2 | ubiquitin associated protein 2 | 0.0286858 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0285021 |
| PARD3 | par-3 family cell polarity regulator | 0.0283743 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.028172 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0277589 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0277386 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0276766 |
| SDC4 | syndecan 4 | 0.0275922 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0270013 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0268198 |
| ATXN1 | ataxin 1 | 0.026793 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.0267512 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0265335 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0262445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.123975 |
| RPS6 | ribosomal protein S6 | -0.085789 |
| NDRG1 | N-myc downstream regulated 1 | -0.083779 |
| B2M | beta-2-microglobulin | -0.0823315 |
| TXNIP | thioredoxin interacting protein | -0.077528 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0757421 |
| HLA-B | major histocompatibility complex, class I, B | -0.0692518 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0577338 |
| RPL35A | ribosomal protein L35a | -0.0575046 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0539718 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0523365 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0507643 |
| RNF43 | ring finger protein 43 | -0.0505023 |
| RNF149 | ring finger protein 149 | -0.0503462 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0472356 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0443505 |
| RPLP1 | ribosomal protein, large, P1 | -0.0442768 |
| AHI1 | Abelson helper integration site 1 | -0.0424329 |
| RPL34 | ribosomal protein L34 | -0.042313 |
| LCN2 | lipocalin 2 | -0.0408942 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0385844 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0380856 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0374939 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0373388 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0367167 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0363136 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0357932 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0353777 |
| RPS19 | ribosomal protein S19 | -0.0348074 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0345695 |
| RPL19 | ribosomal protein L19 | -0.0341921 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0337749 |
| RPL12 | ribosomal protein L12 | -0.0336775 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0333536 |
| GNAS | GNAS complex locus | -0.0329776 |
| IFNGR1 | interferon gamma receptor 1 | -0.0328639 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0327179 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0326798 |
| RUNX1 | runt-related transcription factor 1 | -0.0323895 |
| RPL23 | ribosomal protein L23 | -0.0321557 |
| GOLGA4 | golgin A4 | -0.0319902 |
| HLA-C | major histocompatibility complex, class I, C | -0.0318476 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0316578 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0316175 |
| USP3 | ubiquitin specific peptidase 3 | -0.0313768 |
| IL20RA | interleukin 20 receptor, alpha | -0.0313438 |
| S100A9 | S100 calcium binding protein A9 | -0.0307421 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0299273 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0298307 |
| PTEN | phosphatase and tensin homolog | -0.0298211 |
| DSTN | destrin (actin depolymerizing factor) | -0.0296295 |
| MATR3 | matrin 3 | -0.0289638 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0286261 |
| METTL15 | methyltransferase like 15 | -0.0280886 |
| PKM | pyruvate kinase, muscle | -0.0271606 |
| RPL11 | ribosomal protein L11 | -0.0269442 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.026637 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0263557 |
| RPL28 | ribosomal protein L28 | -0.0261144 |
| PRRC2C | proline-rich coiled-coil 2C | -0.025154 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0247924 |
| PGK1 | phosphoglycerate kinase 1 | -0.0246759 |
| RPL37A | ribosomal protein L37a | -0.0243804 |
| MT2A | metallothionein 2A | -0.0241365 |
| SSR1 | signal sequence receptor, alpha | -0.0241276 |
| DNM2 | dynamin 2 | -0.0241267 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0240356 |
| DIAPH3 | diaphanous-related formin 3 | -0.0240107 |
| DENND4C | DENN/MADD domain containing 4C | -0.0239508 |
| HBS1L | HBS1-like translational GTPase | -0.0235515 |
| CANX | calnexin | -0.0235435 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.023434 |
| PTMA | prothymosin, alpha | -0.0232244 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0231342 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0230302 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0227671 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0226837 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0225791 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0225603 |
| RPS28 | ribosomal protein S28 | -0.022542 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.022542 |
| RPS27 | ribosomal protein S27 | -0.0224564 |
| RPL36A | ribosomal protein L36a | -0.0224401 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0224353 |
| XPO1 | exportin 1 | -0.0224237 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0224159 |
| EPCAM | epithelial cell adhesion molecule | -0.0224101 |
| AOPEP | aminopeptidase O (putative) | -0.022403 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0223437 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0218387 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0217042 |
| NCKAP5 | NCK-associated protein 5 | -0.021633 |
| MKI67 | marker of proliferation Ki-67 | -0.0216121 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.021434 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0212741 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0212699 |
| ZNF638 | zinc finger protein 638 | -0.0212681 |
| H1-0 | H1.0 linker histone | -0.0212084 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0209014 |
| RPL37 | ribosomal protein L37 | -0.0208643 |
