| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gemfibrozil_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.21569 |
| SLC38A2 | solute carrier family 38, member 2 | 0.156702 |
| EHBP1 | EH domain binding protein 1 | 0.10538 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0898537 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0826925 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0802679 |
| FAM107B | family with sequence similarity 107, member B | 0.0684359 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0672371 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0659056 |
| C3 | complement component 3 | 0.0629454 |
| FOXP1 | forkhead box P1 | 0.0626159 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0615696 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0593967 |
| DSPP | dentin sialophosphoprotein | 0.0592085 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0587007 |
| CPE | carboxypeptidase E | 0.0584341 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0561537 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0561318 |
| GPC3 | glypican 3 | 0.0557453 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0550523 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0545944 |
| TNS1 | tensin 1 | 0.0535284 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0518195 |
| VMP1 | vacuole membrane protein 1 | 0.0495944 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0456919 |
| SVIL | supervillin | 0.0446234 |
| GPC6 | glypican 6 | 0.0435044 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0433568 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0425184 |
| RAD51B | RAD51 paralog B | 0.0423152 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0414283 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0413204 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0410023 |
| PEG10 | paternally expressed 10 | 0.040391 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0400197 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0394532 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0385992 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0385789 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0375525 |
| PTCHD4 | patched domain containing 4 | 0.0372484 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0361006 |
| SET | SET nuclear proto-oncogene | 0.0358972 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.035439 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0353151 |
| TNS3 | tensin 3 | 0.0348139 |
| VEGFA | vascular endothelial growth factor A | 0.034561 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0340808 |
| ATXN1 | ataxin 1 | 0.0334857 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.033159 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0331258 |
| CNKSR3 | CNKSR family member 3 | 0.032992 |
| CP | ceruloplasmin (ferroxidase) | 0.0328538 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0326258 |
| SEPTIN9 | septin 9 | 0.032441 |
| AHSG | alpha-2-HS-glycoprotein | 0.0323908 |
| DST | dystonin | 0.0323729 |
| ITGA1 | integrin, alpha 1 | 0.0322994 |
| DUSP6 | dual specificity phosphatase 6 | 0.0316974 |
| RIGI | RNA sensor RIG-I | 0.0316513 |
| EGR1 | early growth response 1 | 0.0314397 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0304803 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0303787 |
| VCL | vinculin | 0.0303133 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0302044 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0300431 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0295728 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0295447 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0294745 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0293368 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0292407 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0290843 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | 0.0288738 |
| SDC2 | syndecan 2 | 0.0286731 |
| RIN2 | Ras and Rab interactor 2 | 0.028389 |
| CUL3 | cullin 3 | 0.0279644 |
| JAK1 | Janus kinase 1 | 0.0276689 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.027591 |
| MYO1E | myosin IE | 0.0274604 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0271476 |
| RPS3 | ribosomal protein S3 | 0.0269997 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.026804 |
| JMJD1C | jumonji domain containing 1C | 0.026596 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0265478 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0263388 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0260068 |
| FAT1 | FAT atypical cadherin 1 | 0.026003 |
| FILIP1L | filamin A interacting protein 1-like | 0.0259193 |
| CRY1 | cryptochrome circadian clock 1 | 0.0254886 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0254504 |
| GK | glycerol kinase | 0.025204 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0248317 |
| ADIPOR2 | adiponectin receptor 2 | 0.0248054 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0246103 |
| PRKCA | protein kinase C, alpha | 0.0243689 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0242142 |
| SMAD3 | SMAD family member 3 | 0.0241661 |
| CADM1 | cell adhesion molecule 1 | 0.0241556 |
| BCL2L1 | BCL2-like 1 | 0.0241089 |
| WDR43 | WD repeat domain 43 | 0.0240853 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0240812 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.288942 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.177559 |
| MT2A | metallothionein 2A | -0.119329 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0906105 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0807106 |
| RPS6 | ribosomal protein S6 | -0.0746133 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0720964 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0714199 |
| RPLP1 | ribosomal protein, large, P1 | -0.0704716 |
| RPL34 | ribosomal protein L34 | -0.0699899 |
| APOA2 | apolipoprotein A-II | -0.0684192 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0681101 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.065186 |
| RPL11 | ribosomal protein L11 | -0.0648426 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.063718 |
| DTNA | dystrobrevin, alpha | -0.0629799 |
| PLIN2 | perilipin 2 | -0.062204 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0582361 |
| TMSB10 | thymosin beta 10 | -0.0580134 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0569695 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.05509 |
| RPS19 | ribosomal protein S19 | -0.0539497 |
| RPL23 | ribosomal protein L23 | -0.053349 |
| SBF2 | SET binding factor 2 | -0.0530361 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.052887 |
| RPL35A | ribosomal protein L35a | -0.0519594 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0519034 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0473402 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0467151 |
| RPS21 | ribosomal protein S21 | -0.0458833 |
| ZNF292 | zinc finger protein 292 | -0.045334 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0450721 |
| RPLP0 | ribosomal protein, large, P0 | -0.04424 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0441198 |
| NDRG1 | N-myc downstream regulated 1 | -0.0440128 |
| RPL12 | ribosomal protein L12 | -0.0435194 |
| H1-0 | H1.0 linker histone | -0.0430143 |
| RPLP2 | ribosomal protein, large, P2 | -0.0429964 |
| APOE | apolipoprotein E | -0.0423892 |
| S100A9 | S100 calcium binding protein A9 | -0.0421543 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0402648 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0401535 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0347809 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0344557 |
| INSIG2 | insulin induced gene 2 | -0.0342853 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0340311 |
| KRT18 | keratin 18, type I | -0.0340242 |
| NUP58 | nucleoporin 58 | -0.0335293 |
| RPL19 | ribosomal protein L19 | -0.0333095 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.032244 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0322387 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0316268 |
| RPS14 | ribosomal protein S14 | -0.0314541 |
| RPL27 | ribosomal protein L27 | -0.0313605 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0311231 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0310593 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0307811 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0304836 |
| SRPK1 | SRSF protein kinase 1 | -0.0297917 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.029601 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0293294 |
| GOLGA4 | golgin A4 | -0.0290715 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0289936 |
| FTL | ferritin, light polypeptide | -0.0289566 |
| SQSTM1 | sequestosome 1 | -0.0287967 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0287494 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0285182 |
| RPS27A | ribosomal protein S27a | -0.028381 |
| HMGA1 | high mobility group AT-hook 1 | -0.0282543 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0278504 |
| WDR45B | WD repeat domain 45B | -0.0278119 |
| RPS8 | ribosomal protein S8 | -0.0273881 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0272886 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0271556 |
| KRT8 | keratin 8, type II | -0.0270674 |
| APOC1 | apolipoprotein C-I | -0.0269184 |
| RPS16 | ribosomal protein S16 | -0.0269105 |
| KIAA1217 | KIAA1217 | -0.0267523 |
| RPS5 | ribosomal protein S5 | -0.0265833 |
| RPS11 | ribosomal protein S11 | -0.0265768 |
| FAM162A | family with sequence similarity 162, member A | -0.0263979 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0261558 |
| VIM | vimentin | -0.0261427 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0260867 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.0257011 |
| ABAT | 4-aminobutyrate aminotransferase | -0.0256725 |
| SEPTIN2 | septin 2 | -0.0256621 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0256245 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0254913 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0252424 |
| GLG1 | golgi glycoprotein 1 | -0.0251242 |
| RPS20 | ribosomal protein S20 | -0.0251045 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0250472 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0249396 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0243014 |
| RPS23 | ribosomal protein S23 | -0.0240638 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0239918 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0233651 |
| RUNX1 | runt-related transcription factor 1 | -0.0232627 |
| MATR3 | matrin 3 | -0.0230757 |
