| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemfibrozil_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.225781 |
| EMP1 | epithelial membrane protein 1 | 0.179632 |
| ANXA1 | annexin A1 | 0.127586 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0997649 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0955358 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0937692 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0933903 |
| EZR | ezrin | 0.0847639 |
| ASPH | aspartate beta-hydroxylase | 0.0794822 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0768253 |
| TMC5 | transmembrane channel-like 5 | 0.07383 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0701441 |
| SLC38A2 | solute carrier family 38, member 2 | 0.067425 |
| VEGFA | vascular endothelial growth factor A | 0.0666148 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0603753 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0602542 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0592724 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0586661 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0567539 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0559775 |
| GDA | guanine deaminase | 0.0540721 |
| ITGA6 | integrin, alpha 6 | 0.053641 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0533107 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0500396 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0494886 |
| EFNA5 | ephrin-A5 | 0.0491946 |
| ENO1 | enolase 1, (alpha) | 0.0488337 |
| SIK3 | SIK family kinase 3 | 0.048566 |
| SET | SET nuclear proto-oncogene | 0.0465318 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0451452 |
| INTS6 | integrator complex subunit 6 | 0.0442294 |
| DSPP | dentin sialophosphoprotein | 0.0415123 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0412225 |
| AGR3 | anterior gradient 3 | 0.040751 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0397585 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0393333 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.03926 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0387322 |
| UBC | ubiquitin C | 0.038485 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0376506 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0357903 |
| PKM | pyruvate kinase, muscle | 0.0347934 |
| DST | dystonin | 0.0345125 |
| EFNB2 | ephrin-B2 | 0.0342767 |
| MYO1E | myosin IE | 0.0341908 |
| SGMS2 | sphingomyelin synthase 2 | 0.034012 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0338142 |
| FRMD5 | FERM domain containing 5 | 0.0337492 |
| RASEF | RAS and EF-hand domain containing | 0.0336079 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0333737 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0332128 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0319901 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0315241 |
| CALR | calreticulin | 0.0310969 |
| MYOF | myoferlin | 0.0306797 |
| GOLGB1 | golgin B1 | 0.0293618 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.02927 |
| MED13 | mediator complex subunit 13 | 0.028762 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0286041 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0281509 |
| BRD2 | bromodomain containing 2 | 0.0277668 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0277369 |
| YAP1 | Yes-associated protein 1 | 0.0276632 |
| TJP1 | tight junction protein 1 | 0.0274617 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0268367 |
| COBL | cordon-bleu WH2 repeat protein | 0.0268241 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0264939 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0262958 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0261388 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0257265 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0255414 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0253069 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0251367 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0250354 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0250262 |
| MYADM | myeloid-associated differentiation marker | 0.0249839 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0249247 |
| SEPTIN9 | septin 9 | 0.0249049 |
| CCNY | cyclin Y | 0.0247711 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0247171 |
| LDHA | lactate dehydrogenase A | 0.0246897 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0245052 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0244672 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0240766 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0239526 |
| FAM107B | family with sequence similarity 107, member B | 0.0238533 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0238508 |
| GRB10 | growth factor receptor-bound protein 10 | 0.023718 |
| DSTN | destrin (actin depolymerizing factor) | 0.0236026 |
| AHR | aryl hydrocarbon receptor | 0.0235796 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0234505 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0234231 |
| MACROD2 | MACRO domain containing 2 | 0.023385 |
| MPZL3 | myelin protein zero-like 3 | 0.0232133 |
| FNIP1 | folliculin interacting protein 1 | 0.0231869 |
| FAT1 | FAT atypical cadherin 1 | 0.0230549 |
| LCN2 | lipocalin 2 | 0.0230229 |
| FBXO11 | F-box protein 11 | 0.0229171 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0229115 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0227599 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.145716 |
| NPSR1 | neuropeptide S receptor 1 | -0.108925 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0989183 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0920198 |
| TMSB10 | thymosin beta 10 | -0.0902924 |
| S100A6 | S100 calcium binding protein A6 | -0.0862729 |
| KRT18 | keratin 18, type I | -0.0796031 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0779757 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0688865 |
| RPL23 | ribosomal protein L23 | -0.0673931 |
| RPL35A | ribosomal protein L35a | -0.067387 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0620708 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0610833 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0606519 |
| RPS6 | ribosomal protein S6 | -0.0601771 |
| RPS21 | ribosomal protein S21 | -0.0586024 |
| H1-0 | H1.0 linker histone | -0.0572207 |
| PRSS3 | protease, serine, 3 | -0.05647 |
| RPL34 | ribosomal protein L34 | -0.054045 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0522676 |
| FLNB | filamin B, beta | -0.0499079 |
| RPS19 | ribosomal protein S19 | -0.0493233 |
| GOLGA4 | golgin A4 | -0.0483463 |
| KRT8 | keratin 8, type II | -0.0478083 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0470328 |
| S100P | S100 calcium binding protein P | -0.0456147 |
| HLA-C | major histocompatibility complex, class I, C | -0.0446369 |
| S100A9 | S100 calcium binding protein A9 | -0.0440469 |
| ITGB4 | integrin, beta 4 | -0.0419176 |
| S100A10 | S100 calcium binding protein A10 | -0.0415523 |
| RPS24 | ribosomal protein S24 | -0.0396639 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0395065 |
| RPL26 | ribosomal protein L26 | -0.0390685 |
| RPL12 | ribosomal protein L12 | -0.0386305 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0380858 |
| RRBP1 | ribosome binding protein 1 | -0.0372752 |
| RPLP1 | ribosomal protein, large, P1 | -0.0372007 |
| GNAS | GNAS complex locus | -0.0369444 |
| PTMA | prothymosin, alpha | -0.0369378 |
| GPX2 | glutathione peroxidase 2 | -0.0366817 |
| JUP | junction plakoglobin | -0.035776 |
| TRIM31 | tripartite motif containing 31 | -0.0342242 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0341024 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0340778 |
| RPL11 | ribosomal protein L11 | -0.0326603 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.032505 |
| AGR2 | anterior gradient 2 | -0.0323697 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0320861 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0318512 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0305131 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0297639 |
| MUC17 | mucin 17, cell surface associated | -0.029369 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0290845 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0283797 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0278039 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0277997 |
| KRT17 | keratin 17, type I | -0.0265694 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0265221 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0259816 |
| GSTP1 | glutathione S-transferase pi 1 | -0.02585 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0258007 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0255236 |
| RPS25 | ribosomal protein S25 | -0.0252997 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0251426 |
| FASN | fatty acid synthase | -0.0249132 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0243908 |
| HLA-A | major histocompatibility complex, class I, A | -0.0243785 |
| ACTN4 | actinin, alpha 4 | -0.0241839 |
| KRT7 | keratin 7, type II | -0.0240695 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0240248 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0240223 |
| HMGA1 | high mobility group AT-hook 1 | -0.0240166 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0238361 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0236936 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0236354 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.023604 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0235763 |
| KRT19 | keratin 19, type I | -0.0234326 |
| RPL32 | ribosomal protein L32 | -0.0233295 |
| RPS5 | ribosomal protein S5 | -0.0232038 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -0.023158 |
| FOXK2 | forkhead box K2 | -0.0227255 |
| MUC1 | mucin 1, cell surface associated | -0.0227185 |
| MYL12B | myosin, light chain 12B, regulatory | -0.022539 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0224417 |
| ACTG1 | actin gamma 1 | -0.022323 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0223032 |
| CLTC | clathrin, heavy chain (Hc) | -0.0222966 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0222711 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0222358 |
| CEP95 | centrosomal protein 95kDa | -0.0220212 |
| LYZ | lysozyme | -0.0220062 |
| TRIM2 | tripartite motif containing 2 | -0.0218968 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0213015 |
| APOL6 | apolipoprotein L, 6 | -0.0211698 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0210131 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0209494 |
| BCL2L1 | BCL2-like 1 | -0.0208722 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0207968 |
| RNF43 | ring finger protein 43 | -0.0207791 |
