| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Gemfibrozil_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.144108 |
| MT2A | metallothionein 2A | 0.103511 |
| CAPRIN2 | caprin family member 2 | 0.0823549 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0809481 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0693545 |
| FMNL2 | formin-like 2 | 0.0687814 |
| ANGPTL4 | angiopoietin-like 4 | 0.0667499 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0577452 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0575727 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0575239 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0544477 |
| MT1X | metallothionein 1X | 0.0532415 |
| RAB7A | RAB7A, member RAS oncogene family | 0.052133 |
| CD44 | CD44 molecule (Indian blood group) | 0.0514803 |
| MYOF | myoferlin | 0.0512383 |
| NAV2 | neuron navigator 2 | 0.0500788 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0500203 |
| JUN | jun proto-oncogene | 0.047067 |
| TXNIP | thioredoxin interacting protein | 0.0470414 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0469623 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0462255 |
| UBC | ubiquitin C | 0.0456106 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0450394 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0447751 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0439304 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0422549 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0409704 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0409524 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0409252 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.040433 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0403204 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0402632 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0397819 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0388257 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0386951 |
| ANKRD36 | ankyrin repeat domain 36 | 0.036647 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0364773 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0359723 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.035113 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0348236 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0336758 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0335494 |
| VEGFA | vascular endothelial growth factor A | 0.0333408 |
| LYST | lysosomal trafficking regulator | 0.0328898 |
| SLK | STE20-like kinase | 0.0323012 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0321335 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.032042 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0320175 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0316804 |
| SEC24A | SEC24 family member A | 0.0314154 |
| FTL | ferritin, light polypeptide | 0.0311709 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0310882 |
| MT1E | metallothionein 1E | 0.0310575 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0309778 |
| B2M | beta-2-microglobulin | 0.0308586 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0308517 |
| BBX | bobby sox homolog (Drosophila) | 0.0297938 |
| RPS3 | ribosomal protein S3 | 0.0295305 |
| DNER | delta/notch-like EGF repeat containing | 0.0294477 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0293432 |
| RIOK3 | RIO kinase 3 | 0.0290418 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0289441 |
| PCDH1 | protocadherin 1 | 0.0286424 |
| EPHA4 | EPH receptor A4 | 0.0281733 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0279187 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0278642 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0277041 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0276852 |
| ZNF292 | zinc finger protein 292 | 0.0274654 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0273073 |
| SET | SET nuclear proto-oncogene | 0.0272934 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0271755 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0268377 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0267974 |
| SMYD3 | SET and MYND domain containing 3 | 0.0267674 |
| KLF6 | Kruppel-like factor 6 | 0.0267293 |
| ARFGEF3 | ARFGEF family member 3 | 0.0264221 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0259404 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0255436 |
| APP | amyloid beta (A4) precursor protein | 0.0253607 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0252931 |
| PLK2 | polo-like kinase 2 | 0.0252414 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0248174 |
| SETD5 | SET domain containing 5 | 0.0240808 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0240683 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.02398 |
| PRELID2 | PRELI domain containing 2 | 0.023871 |
| PDE10A | phosphodiesterase 10A | 0.0234454 |
| NDRG1 | N-myc downstream regulated 1 | 0.0234318 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0234274 |
| SQSTM1 | sequestosome 1 | 0.0234006 |
| SP100 | SP100 nuclear antigen | 0.0232628 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0232484 |
| TMF1 | TATA element modulatory factor 1 | 0.0230328 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0228844 |
| INTS6 | integrator complex subunit 6 | 0.0228556 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0226796 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0226334 |
| ENO1 | enolase 1, (alpha) | 0.0225659 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0224301 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.108293 |
| TMSB10 | thymosin beta 10 | -0.105445 |
| VIM | vimentin | -0.0870045 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.07999 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0792957 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0759559 |
| CENPF | centromere protein F, 350/400kDa | -0.063476 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0621965 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0611533 |
| ACTG1 | actin gamma 1 | -0.0585441 |
| TMSB4X | thymosin beta 4, X-linked | -0.0557518 |
| RAI1 | retinoic acid induced 1 | -0.054913 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0471586 |
| MKI67 | marker of proliferation Ki-67 | -0.0458619 |
| RPL23 | ribosomal protein L23 | -0.0440454 |
| RPL35A | ribosomal protein L35a | -0.0431137 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0426182 |
| PYGB | phosphorylase, glycogen; brain | -0.0425738 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0422107 |
| RIGI | RNA sensor RIG-I | -0.0403649 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0400307 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0374163 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0367477 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.0360134 |
| AHNAK | AHNAK nucleoprotein | -0.035349 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.035347 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0351179 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0337859 |
| HDLBP | high density lipoprotein binding protein | -0.0335855 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0335317 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0332694 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0326788 |
| ETNK1 | ethanolamine kinase 1 | -0.0326534 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.032538 |
| RPS21 | ribosomal protein S21 | -0.0317055 |
| TMEM41B | transmembrane protein 41B | -0.0314826 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0303705 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0299761 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0286554 |
| DIAPH3 | diaphanous-related formin 3 | -0.027689 |
| SRGN | serglycin | -0.0275924 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0273418 |
| RBM25 | RNA binding motif protein 25 | -0.0273404 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0272122 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0272062 |
| RPS6 | ribosomal protein S6 | -0.0270528 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0267128 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0266769 |
| HJURP | Holliday junction recognition protein | -0.0265557 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0263227 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0263008 |
| FBXO34 | F-box protein 34 | -0.0260762 |
| ANLN | anillin, actin binding protein | -0.0259975 |
| TPX2 | TPX2, microtubule-associated | -0.0258982 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.025863 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0257723 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0256062 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0251508 |
| MYO10 | myosin X | -0.0251061 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0250375 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0249093 |
| FBXO11 | F-box protein 11 | -0.0248317 |
| XPO1 | exportin 1 | -0.024785 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0247106 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0245234 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0243472 |
| PODXL | podocalyxin-like | -0.0242989 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0242692 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0242549 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0242453 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0239647 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0238933 |
| NUP153 | nucleoporin 153kDa | -0.023705 |
| CAPRIN1 | cell cycle associated protein 1 | -0.023689 |
| KIF14 | kinesin family member 14 | -0.0236604 |
| ANKRD17 | ankyrin repeat domain 17 | -0.023391 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0231694 |
| CFDP1 | craniofacial development protein 1 | -0.0231135 |
| ECT2 | epithelial cell transforming 2 | -0.0231024 |
| RPL5 | ribosomal protein L5 | -0.0229792 |
| TOP1 | topoisomerase (DNA) I | -0.0227918 |
| RTN4 | reticulon 4 | -0.0225509 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0224133 |
| CAVIN1 | caveolae associated protein 1 | -0.0223996 |
| SETX | senataxin | -0.0223581 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0221437 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0220723 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0218494 |
| RPL19 | ribosomal protein L19 | -0.0217462 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0217364 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0215667 |
| VCL | vinculin | -0.0214719 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0213942 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.021336 |
| FERMT1 | fermitin family member 1 | -0.021316 |
| SGO2 | shugoshin 2 | -0.0212859 |
| ZNF721 | zinc finger protein 721 | -0.0212803 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0212209 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0211519 |
| MAP4 | microtubule-associated protein 4 | -0.0210517 |
