| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gemfibrozil_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.0981564 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.072401 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0692208 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0687205 |
| INTS6 | integrator complex subunit 6 | 0.0544749 |
| DSPP | dentin sialophosphoprotein | 0.0538673 |
| SLTM | SAFB-like, transcription modulator | 0.047561 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0421516 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0411986 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0411431 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0409399 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0408708 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0382078 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0375817 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.03656 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0364312 |
| GOLGB1 | golgin B1 | 0.0343231 |
| ANXA1 | annexin A1 | 0.0324841 |
| HOMER1 | homer scaffolding protein 1 | 0.0319807 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0315274 |
| SIK3 | SIK family kinase 3 | 0.0312815 |
| PYGL | phosphorylase, glycogen, liver | 0.0312757 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0310651 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0306278 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0303499 |
| MORF4L2 | mortality factor 4 like 2 | 0.0294284 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0293052 |
| EGR1 | early growth response 1 | 0.0287974 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0285121 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0281457 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0281157 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0275975 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0273407 |
| H1-0 | H1.0 linker histone | 0.0272915 |
| MYO1E | myosin IE | 0.0272849 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0257841 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0253597 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.025191 |
| MCL1 | myeloid cell leukemia 1 | 0.0251243 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0250552 |
| EZR | ezrin | 0.0244322 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0226977 |
| BMP6 | bone morphogenetic protein 6 | 0.0223874 |
| FAM13A | family with sequence similarity 13, member A | 0.0223177 |
| AREG | amphiregulin | 0.0220623 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.021758 |
| NABP1 | nucleic acid binding protein 1 | 0.0215896 |
| ATF6 | activating transcription factor 6 | 0.0215866 |
| RPL3 | ribosomal protein L3 | 0.0211594 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0210864 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0209251 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0206507 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0189968 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0188524 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0188388 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0184399 |
| HBP1 | HMG-box transcription factor 1 | 0.0183026 |
| ATXN1 | ataxin 1 | 0.0182806 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0182711 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0180146 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0178652 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0176605 |
| ENSA | endosulfine alpha | 0.0173969 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0173206 |
| VEGFA | vascular endothelial growth factor A | 0.0172129 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0168811 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0167993 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0166345 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.0164263 |
| EMP1 | epithelial membrane protein 1 | 0.0163587 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0163367 |
| CES1 | carboxylesterase 1 | 0.0160123 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0158599 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0157916 |
| LAMB3 | laminin, beta 3 | 0.0157029 |
| TOP1 | topoisomerase (DNA) I | 0.0153598 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0151728 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0149156 |
| MYO6 | myosin VI | 0.0145393 |
| MYO5B | myosin VB | 0.0144323 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0143896 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.014331 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0142238 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0141892 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0141382 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0139397 |
| USP53 | ubiquitin specific peptidase 53 | 0.0137499 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0136824 |
| ATP11A | ATPase, class VI, type 11A | 0.0134077 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0131308 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0130673 |
| RBM39 | RNA binding motif protein 39 | 0.0130432 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0130252 |
| TLE4 | transducin-like enhancer of split 4 | 0.0130132 |
| HMGA2 | high mobility group AT-hook 2 | 0.0129738 |
| EGFR | epidermal growth factor receptor | 0.0129621 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0129475 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0128546 |
| SVIL | supervillin | 0.0127486 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0126789 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.312244 |
| TXNRD1 | thioredoxin reductase 1 | -0.273719 |
| TMSB10 | thymosin beta 10 | -0.200856 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.156082 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.152868 |
| UBC | ubiquitin C | -0.144689 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.113404 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0885071 |
| RPS27A | ribosomal protein S27a | -0.078846 |
| PCBP2 | poly(rC) binding protein 2 | -0.0773153 |
| PKM | pyruvate kinase, muscle | -0.073322 |
| CST3 | cystatin C | -0.0731552 |
| ASPH | aspartate beta-hydroxylase | -0.0722597 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0705892 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.069803 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0690389 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0670706 |
| FTL | ferritin, light polypeptide | -0.0662622 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0645595 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0642324 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0590229 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0587035 |
| KRT7 | keratin 7, type II | -0.0572955 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0568212 |
| PTMA | prothymosin, alpha | -0.0564843 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0525586 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0519744 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0518152 |
| OSMR | oncostatin M receptor | -0.0516848 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0507634 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0497094 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0492238 |
| RPS25 | ribosomal protein S25 | -0.0486306 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0484313 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0461776 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0450772 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0416249 |
| RAB10 | RAB10, member RAS oncogene family | -0.041361 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.040026 |
| B2M | beta-2-microglobulin | -0.0398479 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0393164 |
| S100A6 | S100 calcium binding protein A6 | -0.0377636 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0372639 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0370575 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0354278 |
| CCND1 | cyclin D1 | -0.0347524 |
| RPL35A | ribosomal protein L35a | -0.0342493 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0336659 |
| RPL37A | ribosomal protein L37a | -0.0336289 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0335315 |
| TNS3 | tensin 3 | -0.0328497 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0328336 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0325667 |
| TMEM165 | transmembrane protein 165 | -0.0320149 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0318749 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0318343 |
| KRT18 | keratin 18, type I | -0.0316168 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0315117 |
| RNF213 | ring finger protein 213 | -0.0313164 |
| S100A9 | S100 calcium binding protein A9 | -0.0312313 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0310644 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0305418 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0305347 |
| SEC61G | Sec61 gamma subunit | -0.0299472 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0298053 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0297209 |
| ACTG1 | actin gamma 1 | -0.0295342 |
| RPS3 | ribosomal protein S3 | -0.0294622 |
| MKI67 | marker of proliferation Ki-67 | -0.0292311 |
| TPD52 | tumor protein D52 | -0.0291764 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0291669 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0289769 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0284557 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0283976 |
| ANXA2 | annexin A2 | -0.028043 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0273359 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0273037 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0270572 |
| KRT8 | keratin 8, type II | -0.026913 |
| MT2A | metallothionein 2A | -0.0267995 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0266843 |
| CCNI | cyclin I | -0.0260232 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0259666 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0258294 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0257249 |
| USP34 | ubiquitin specific peptidase 34 | -0.0255887 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0255675 |
| RNF145 | ring finger protein 145 | -0.0252068 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0251258 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.025115 |
| HLA-B | major histocompatibility complex, class I, B | -0.0249522 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0244195 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0243396 |
| ENO1 | enolase 1, (alpha) | -0.0243094 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0240691 |
| GNAS | GNAS complex locus | -0.0239949 |
| FNDC3B | fibronectin type III domain containing 3B | -0.023967 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0236929 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0236928 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0232379 |
