| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gemfibrozil perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gemfibrozil_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.272181 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.1642 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.125376 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0814126 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0738479 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0732798 |
| KYNU | kynureninase | 0.0712741 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0694459 |
| ASPH | aspartate beta-hydroxylase | 0.0681419 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0633547 |
| FAM107B | family with sequence similarity 107, member B | 0.0555973 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0551792 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0527848 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0523604 |
| TOP1 | topoisomerase (DNA) I | 0.0513502 |
| TPM3 | tropomyosin 3 | 0.0509733 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0499734 |
| GRAMD1B | GRAM domain containing 1B | 0.0497014 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0486061 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0483069 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0463527 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0448865 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0441487 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0435359 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.043418 |
| WWOX | WW domain containing oxidoreductase | 0.0430363 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0420509 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0419732 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0418761 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0418663 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0407959 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0404548 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.04025 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.039544 |
| INTS6 | integrator complex subunit 6 | 0.0390959 |
| UBC | ubiquitin C | 0.0388212 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0388057 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0378302 |
| MYOF | myoferlin | 0.0377407 |
| CUL3 | cullin 3 | 0.0369532 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0369473 |
| COPA | coatomer protein complex, subunit alpha | 0.0367274 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0362683 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0361994 |
| SPAG9 | sperm associated antigen 9 | 0.0357749 |
| PDLIM5 | PDZ and LIM domain 5 | 0.035705 |
| BRD2 | bromodomain containing 2 | 0.0356211 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0355417 |
| VCL | vinculin | 0.0352671 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0351636 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0351449 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0349261 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0347967 |
| MED13 | mediator complex subunit 13 | 0.0346661 |
| GOLGB1 | golgin B1 | 0.0343634 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0343626 |
| KIF5B | kinesin family member 5B | 0.0339729 |
| SON | SON DNA binding protein | 0.0339548 |
| RPL26 | ribosomal protein L26 | 0.0339157 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0338082 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0335505 |
| LDHA | lactate dehydrogenase A | 0.0335386 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0324465 |
| RPL23 | ribosomal protein L23 | 0.032284 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0320547 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0320192 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0318532 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0318319 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0311888 |
| ZNF644 | zinc finger protein 644 | 0.0310767 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0309379 |
| FUS | FUS RNA binding protein | 0.0309232 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0308389 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0305911 |
| ACTG1 | actin gamma 1 | 0.0304703 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0301669 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0300011 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0297897 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0296327 |
| TASOR2 | transcription activation suppressor family member 2 | 0.029295 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0292757 |
| GOLGA4 | golgin A4 | 0.0292647 |
| RRM2 | ribonucleotide reductase M2 | 0.0292299 |
| RBM39 | RNA binding motif protein 39 | 0.0291984 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0288252 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0283471 |
| VMP1 | vacuole membrane protein 1 | 0.028098 |
| SMAD2 | SMAD family member 2 | 0.0280584 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0279806 |
| IER3 | immediate early response 3 | 0.027966 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0278275 |
| SYNRG | synergin, gamma | 0.0277102 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0274557 |
| RPS8 | ribosomal protein S8 | 0.027177 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0271401 |
| PRELID2 | PRELI domain containing 2 | 0.0269875 |
| BMP6 | bone morphogenetic protein 6 | 0.0269347 |
| ATF6 | activating transcription factor 6 | 0.0269163 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0267374 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0266499 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.241431 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.203911 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165974 |
| VIM | vimentin | -0.162847 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.153688 |
| MT2A | metallothionein 2A | -0.135592 |
| IGF2 | insulin-like growth factor 2 | -0.128163 |
| TMSB10 | thymosin beta 10 | -0.115176 |
| PYGL | phosphorylase, glycogen, liver | -0.112431 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.106548 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0750005 |
| S100A6 | S100 calcium binding protein A6 | -0.0655241 |
| TXNRD1 | thioredoxin reductase 1 | -0.0581732 |
| TPM4 | tropomyosin 4 | -0.0552521 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0484402 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0436923 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0406142 |
| FLNB | filamin B, beta | -0.0399413 |
| OSMR | oncostatin M receptor | -0.0397133 |
| AK1 | adenylate kinase 1 | -0.0396589 |
| FGB | fibrinogen beta chain | -0.0384581 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0371909 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0360181 |
| BICC1 | BicC family RNA binding protein 1 | -0.0344681 |
| RPL35A | ribosomal protein L35a | -0.0342944 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0336246 |
| RPS6 | ribosomal protein S6 | -0.0331867 |
| CD99 | CD99 molecule | -0.0322646 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0316895 |
| NAV3 | neuron navigator 3 | -0.0316506 |
| RPS27 | ribosomal protein S27 | -0.0315695 |
| HDAC9 | histone deacetylase 9 | -0.0314123 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0313695 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0309525 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0309062 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0307585 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0307409 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0299382 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0294993 |
| PTMA | prothymosin, alpha | -0.0292196 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.02891 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0280195 |
| MAP1B | microtubule-associated protein 1B | -0.0271529 |
| NEGR1 | neuronal growth regulator 1 | -0.0269948 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0263771 |
| LAMB1 | laminin, beta 1 | -0.0257319 |
| RPS19 | ribosomal protein S19 | -0.0248891 |
| CMIP | c-Maf inducing protein | -0.0246945 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0238972 |
| HMGA2 | high mobility group AT-hook 2 | -0.0238314 |
| RAD51B | RAD51 paralog B | -0.0238072 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.023758 |
| DENND5B | DENN/MADD domain containing 5B | -0.0236941 |
| GLIS3 | GLIS family zinc finger 3 | -0.023583 |
| NEBL | nebulette | -0.0232534 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0229614 |
| PCED1B | PC-esterase domain containing 1B | -0.0225918 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0221321 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0221042 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.022047 |
| TPD52 | tumor protein D52 | -0.0220126 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0215601 |
| HLA-B | major histocompatibility complex, class I, B | -0.0215467 |
| RIN2 | Ras and Rab interactor 2 | -0.0211169 |
| RPL36 | ribosomal protein L36 | -0.0211043 |
| RPS21 | ribosomal protein S21 | -0.0210933 |
| EGR1 | early growth response 1 | -0.0210773 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0208151 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0207191 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0205438 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0204398 |
| EFNA5 | ephrin-A5 | -0.0204092 |
| TNS3 | tensin 3 | -0.0202682 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0202567 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0202436 |
| PARD3 | par-3 family cell polarity regulator | -0.0202202 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0200768 |
| RPS14 | ribosomal protein S14 | -0.0199646 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0199033 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0198636 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0197896 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0196806 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0195369 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0194591 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0188213 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0188002 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0187768 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0187471 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0186874 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0184243 |
| FDPS | farnesyl diphosphate synthase | -0.01834 |
| CA2 | carbonic anhydrase II | -0.0182935 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0175764 |
| PHKB | phosphorylase kinase, beta | -0.0175107 |
| KIFC3 | kinesin family member C3 | -0.0174773 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0173946 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0173131 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0172786 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0171544 |
| SERF2 | small EDRK-rich factor 2 | -0.017138 |
